Sarcoidosis presenting with severe hypocalcaemia.

Hdl Handle:
http://hdl.handle.net/10147/206310
Title:
Sarcoidosis presenting with severe hypocalcaemia.
Authors:
Saeed, A; Khan, M; Irwin, S; Fraser, A
Affiliation:
Department of Rheumatology, Mid Western Regional Hospital, Dooradoyle, Limerick, , Ireland. modelian@gmail.com
Citation:
Ir J Med Sci. 2011 Jun;180(2):575-7. Epub 2009 Jan 31.
Journal:
Irish journal of medical science
Issue Date:
31-Jan-2012
URI:
http://hdl.handle.net/10147/206310
DOI:
10.1007/s11845-009-0277-9
PubMed ID:
19184607
Abstract:
Disorders of calcium metabolism, especially hypercalcemia and hypercalceuria, are common in sarcoidosis. They are caused by extra renal unsuppressed production of 1,25 dihydroxy vitamin D at the level of the sarcoid granuloma. Hormonal changes during pregnancy have a physiological synergistic effect on this mechanism, which is primarily parathyroid hormone (PTH) dependant. However, the combination of primary hypoparathyroidism with hypocalcemia and sarcoidosis is rare. Di George syndrome, is a dysmorphic disorder characterised by aplasia/hypoplasia of thymus and parathyroid glands in addition to aortic arch anamolies and facial dysmorphia. After commencing appropriate treatment this lady made excellent recovary.
Language:
eng
MeSH:
Adult; Calcium/therapeutic use; DiGeorge Syndrome/*complications/drug therapy/genetics; Female; Humans; Hypocalcemia/drug therapy/etiology; Lymphatic Diseases/*complications; Postpartum Period; Sarcoidosis/*complications/drug therapy; Steroids/therapeutic use; Vitamin D/therapeutic use
ISSN:
1863-4362 (Electronic); 0021-1265 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorSaeed, Aen_GB
dc.contributor.authorKhan, Men_GB
dc.contributor.authorIrwin, Sen_GB
dc.contributor.authorFraser, Aen_GB
dc.date.accessioned2012-01-31T16:46:27Z-
dc.date.available2012-01-31T16:46:27Z-
dc.date.issued2012-01-31T16:46:27Z-
dc.identifier.citationIr J Med Sci. 2011 Jun;180(2):575-7. Epub 2009 Jan 31.en_GB
dc.identifier.issn1863-4362 (Electronic)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid19184607en_GB
dc.identifier.doi10.1007/s11845-009-0277-9en_GB
dc.identifier.urihttp://hdl.handle.net/10147/206310-
dc.description.abstractDisorders of calcium metabolism, especially hypercalcemia and hypercalceuria, are common in sarcoidosis. They are caused by extra renal unsuppressed production of 1,25 dihydroxy vitamin D at the level of the sarcoid granuloma. Hormonal changes during pregnancy have a physiological synergistic effect on this mechanism, which is primarily parathyroid hormone (PTH) dependant. However, the combination of primary hypoparathyroidism with hypocalcemia and sarcoidosis is rare. Di George syndrome, is a dysmorphic disorder characterised by aplasia/hypoplasia of thymus and parathyroid glands in addition to aortic arch anamolies and facial dysmorphia. After commencing appropriate treatment this lady made excellent recovary.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshCalcium/therapeutic useen_GB
dc.subject.meshDiGeorge Syndrome/*complications/drug therapy/geneticsen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshHypocalcemia/drug therapy/etiologyen_GB
dc.subject.meshLymphatic Diseases/*complicationsen_GB
dc.subject.meshPostpartum Perioden_GB
dc.subject.meshSarcoidosis/*complications/drug therapyen_GB
dc.subject.meshSteroids/therapeutic useen_GB
dc.subject.meshVitamin D/therapeutic useen_GB
dc.titleSarcoidosis presenting with severe hypocalcaemia.en_GB
dc.contributor.departmentDepartment of Rheumatology, Mid Western Regional Hospital, Dooradoyle, Limerick, , Ireland. modelian@gmail.comen_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceMunster-

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