Relapsing tubulointerstitial nephritis in an adolescent with inflammatory bowel disease without aminosalicylate exposure.

Hdl Handle:
http://hdl.handle.net/10147/206306
Title:
Relapsing tubulointerstitial nephritis in an adolescent with inflammatory bowel disease without aminosalicylate exposure.
Authors:
Shahrani Muhammad, H S; Peters, C; Casserly, L F; Dorman, A M; Watts, M
Affiliation:
Department of Medicine, Mid-Western Regional Hospital, Dooradoyle, Limerick,, Ireland. nurulislahtaib@hotmail.com
Citation:
Clin Nephrol. 2010 Mar;73(3):250-2.
Journal:
Clinical nephrology
Issue Date:
31-Jan-2012
URI:
http://hdl.handle.net/10147/206306
PubMed ID:
20178728
Abstract:
A 14-year-old boy presented with ongoing constipation as a manifestation of newly diagnosed Crohn's disease (CD) and a concomitant decline in renal function with biopsy-proven interstitial nephritis. Initiation of steroid therapy and mesalazine was associated with an improvement in symptoms and renal function. We describe a rare case of a 5-aminosalicylic acid (5-ASA)-naive patient who developed interstitial nephritis in association with CD with no evidence of other primary glomerulopathy. A unique feature of the case being a profound systemic inflammatory response at the time of diagnosis and a relapse in nephritis 2 months after cessation of mesalazine in the absence of any macroscopic colitis.
Language:
eng
MeSH:
Adolescent; Anti-Inflammatory Agents, Non-Steroidal/adverse effects/*therapeutic use; Biopsy; Crohn Disease/complications/diagnosis; Diagnosis, Differential; Follow-Up Studies; Humans; Inflammatory Bowel Diseases/complications/diagnosis/*drug therapy; Kidney Tubules/pathology; Male; Mesalamine/adverse effects/*therapeutic use; Nephritis, Interstitial/diagnosis/*etiology; Recurrence
ISSN:
0301-0430 (Print); 0301-0430 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorShahrani Muhammad, H Sen_GB
dc.contributor.authorPeters, Cen_GB
dc.contributor.authorCasserly, L Fen_GB
dc.contributor.authorDorman, A Men_GB
dc.contributor.authorWatts, Men_GB
dc.date.accessioned2012-01-31T16:47:48Z-
dc.date.available2012-01-31T16:47:48Z-
dc.date.issued2012-01-31T16:47:48Z-
dc.identifier.citationClin Nephrol. 2010 Mar;73(3):250-2.en_GB
dc.identifier.issn0301-0430 (Print)en_GB
dc.identifier.issn0301-0430 (Linking)en_GB
dc.identifier.pmid20178728en_GB
dc.identifier.urihttp://hdl.handle.net/10147/206306-
dc.description.abstractA 14-year-old boy presented with ongoing constipation as a manifestation of newly diagnosed Crohn's disease (CD) and a concomitant decline in renal function with biopsy-proven interstitial nephritis. Initiation of steroid therapy and mesalazine was associated with an improvement in symptoms and renal function. We describe a rare case of a 5-aminosalicylic acid (5-ASA)-naive patient who developed interstitial nephritis in association with CD with no evidence of other primary glomerulopathy. A unique feature of the case being a profound systemic inflammatory response at the time of diagnosis and a relapse in nephritis 2 months after cessation of mesalazine in the absence of any macroscopic colitis.en_GB
dc.language.isoengen_GB
dc.subject.meshAdolescenten_GB
dc.subject.meshAnti-Inflammatory Agents, Non-Steroidal/adverse effects/*therapeutic useen_GB
dc.subject.meshBiopsyen_GB
dc.subject.meshCrohn Disease/complications/diagnosisen_GB
dc.subject.meshDiagnosis, Differentialen_GB
dc.subject.meshFollow-Up Studiesen_GB
dc.subject.meshHumansen_GB
dc.subject.meshInflammatory Bowel Diseases/complications/diagnosis/*drug therapyen_GB
dc.subject.meshKidney Tubules/pathologyen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMesalamine/adverse effects/*therapeutic useen_GB
dc.subject.meshNephritis, Interstitial/diagnosis/*etiologyen_GB
dc.subject.meshRecurrenceen_GB
dc.titleRelapsing tubulointerstitial nephritis in an adolescent with inflammatory bowel disease without aminosalicylate exposure.en_GB
dc.contributor.departmentDepartment of Medicine, Mid-Western Regional Hospital, Dooradoyle, Limerick,, Ireland. nurulislahtaib@hotmail.comen_GB
dc.identifier.journalClinical nephrologyen_GB
dc.description.provinceMunster-

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