The influence of a eutectic mixture of lidocaine and prilocaine on minor surgical procedures: a randomized controlled double-blind trial.

Hdl Handle:
http://hdl.handle.net/10147/206302
Title:
The influence of a eutectic mixture of lidocaine and prilocaine on minor surgical procedures: a randomized controlled double-blind trial.
Authors:
Shaikh, Faisal M; Naqvi, Syed A; Grace, Pierce A
Affiliation:
Department of Surgery, Mid-Western Regional Hospital, Limerick, Ireland., drsmfaisal@yahoo.com
Citation:
Dermatol Surg. 2009 Jun;35(6):948-51. Epub 2009 Apr 8.
Journal:
Dermatologic surgery : official publication for American Society for Dermatologic, Surgery [et al.]
Issue Date:
31-Jan-2012
URI:
http://hdl.handle.net/10147/206302
DOI:
10.1111/j.1524-4725.2009.01160.x
PubMed ID:
19397664
Abstract:
BACKGROUND: A eutectic mixture of lidocaine and prilocaine (EMLA) has been shown to be effective in reducing pain from needle sticks, including those associated with blood sampling and intravenous insertion. OBJECTIVE: To evaluate the effectiveness of EMLA cream applied before needle puncture for local anesthetic administration before minor surgical procedures in this double-blind, randomized, controlled, parallel-group study. MATERIALS AND METHODS: Patients were randomly assigned to receive EMLA or placebo cream (Aqueous) applied under an occlusive dressing. After the procedure, patients were asked to rate the needle prick and procedure pain on a visual analog scale (0=no pain; 10=maximum pain). RESULTS: A total of 94 minor surgical procedures (49 in EMLA and 45 in control) were performed. The mean needle-stick pain score in the EMLA group was significantly lower than in the control group (2.7 vs. 5.7, p<.001, Mann-Whitney U-test). There was also significantly lower procedure pain in the EMLA group than in the control group (0.83 vs. 1.86, p=.009). There were no complications associated with the use of EMLA. CONCLUSION: EMLA effectively reduces the preprocedural needle-stick pain and procedural pain associated with minor surgical procedures.
Language:
eng
MeSH:
Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Combined/*administration & dosage; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Lidocaine/*administration & dosage; Male; Middle Aged; Ointments; Pain Measurement; Prilocaine/*administration & dosage; Prospective Studies; Surgical Procedures, Minor/*methods; Young Adult
ISSN:
1524-4725 (Electronic); 1076-0512 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorShaikh, Faisal Men_GB
dc.contributor.authorNaqvi, Syed Aen_GB
dc.contributor.authorGrace, Pierce Aen_GB
dc.date.accessioned2012-01-31T16:48:17Z-
dc.date.available2012-01-31T16:48:17Z-
dc.date.issued2012-01-31T16:48:17Z-
dc.identifier.citationDermatol Surg. 2009 Jun;35(6):948-51. Epub 2009 Apr 8.en_GB
dc.identifier.issn1524-4725 (Electronic)en_GB
dc.identifier.issn1076-0512 (Linking)en_GB
dc.identifier.pmid19397664en_GB
dc.identifier.doi10.1111/j.1524-4725.2009.01160.xen_GB
dc.identifier.urihttp://hdl.handle.net/10147/206302-
dc.description.abstractBACKGROUND: A eutectic mixture of lidocaine and prilocaine (EMLA) has been shown to be effective in reducing pain from needle sticks, including those associated with blood sampling and intravenous insertion. OBJECTIVE: To evaluate the effectiveness of EMLA cream applied before needle puncture for local anesthetic administration before minor surgical procedures in this double-blind, randomized, controlled, parallel-group study. MATERIALS AND METHODS: Patients were randomly assigned to receive EMLA or placebo cream (Aqueous) applied under an occlusive dressing. After the procedure, patients were asked to rate the needle prick and procedure pain on a visual analog scale (0=no pain; 10=maximum pain). RESULTS: A total of 94 minor surgical procedures (49 in EMLA and 45 in control) were performed. The mean needle-stick pain score in the EMLA group was significantly lower than in the control group (2.7 vs. 5.7, p<.001, Mann-Whitney U-test). There was also significantly lower procedure pain in the EMLA group than in the control group (0.83 vs. 1.86, p=.009). There were no complications associated with the use of EMLA. CONCLUSION: EMLA effectively reduces the preprocedural needle-stick pain and procedural pain associated with minor surgical procedures.en_GB
dc.language.isoengen_GB
dc.subject.meshAdministration, Topicalen_GB
dc.subject.meshAdolescenten_GB
dc.subject.meshAdulten_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshAnesthetics, Combined/*administration & dosageen_GB
dc.subject.meshDose-Response Relationship, Drugen_GB
dc.subject.meshDouble-Blind Methoden_GB
dc.subject.meshFemaleen_GB
dc.subject.meshFollow-Up Studiesen_GB
dc.subject.meshHumansen_GB
dc.subject.meshLidocaine/*administration & dosageen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshOintmentsen_GB
dc.subject.meshPain Measurementen_GB
dc.subject.meshPrilocaine/*administration & dosageen_GB
dc.subject.meshProspective Studiesen_GB
dc.subject.meshSurgical Procedures, Minor/*methodsen_GB
dc.subject.meshYoung Adulten_GB
dc.titleThe influence of a eutectic mixture of lidocaine and prilocaine on minor surgical procedures: a randomized controlled double-blind trial.en_GB
dc.contributor.departmentDepartment of Surgery, Mid-Western Regional Hospital, Limerick, Ireland., drsmfaisal@yahoo.comen_GB
dc.identifier.journalDermatologic surgery : official publication for American Society for Dermatologic, Surgery [et al.]en_GB
dc.description.provinceMunster-
All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.