Routine testing of liver function before and after elective laparoscopic cholecystectomy: is it necessary?

Hdl Handle:
http://hdl.handle.net/10147/206283
Title:
Routine testing of liver function before and after elective laparoscopic cholecystectomy: is it necessary?
Authors:
Ahmad, Nasir Zaheer
Affiliation:
Mid Western Regional Hospital, Ennis, County Clare, Republic of Ireland., nasirzahmad@gmail.com
Citation:
JSLS. 2011 Jan-Mar;15(1):65-9.
Journal:
JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of, Laparoendoscopic Surgeons
Issue Date:
31-Jan-2012
URI:
http://hdl.handle.net/10147/206283
DOI:
10.4293/108680811X13022985131291
PubMed ID:
21902946
Abstract:
BACKGROUND AND OBJECTIVES: Liver function tests (LFTs) include alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transpeptidase (GGT), alkaline phosphatase (ALP), and bilirubin. The role of routine testing before and after laparoscopic cholecystectomy was evaluated in this study. PATIENTS AND METHODS: A total of 355 patients were retrospectively analyzed by examining the LFTs the day before, the day after, and 3 weeks after the surgery. The Wilcoxon signed-rank test and Student t test were performed to determine statistical significance. RESULTS: Alterations in the serum AST, ALT, and GGT were seen on the first postoperative day. Minor changes were seen in bilirubin and ALP. An overall disturbance in the LFTs was seen in more than two-thirds of the cases. Repeat LFTs performed after 3 weeks on follow-up were found to be within normal limits. CONCLUSION: Mild-to-moderate elevation in preoperative LFTs may not be associated with any deleterious effect, and, in the absence of clinical indications, routine preoperative or postoperative liver function testing is unnecessary.
Language:
eng
MeSH:
Adult; *Cholecystectomy, Laparoscopic; Diagnostic Tests, Routine; Female; Humans; Liver Function Tests/*utilization; Male; Middle Aged; Postoperative Care/utilization; Preoperative Care/utilization; Unnecessary Procedures/*utilization
ISSN:
1086-8089 (Print); 1086-8089 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorAhmad, Nasir Zaheeren_GB
dc.date.accessioned2012-01-31T16:48:22Z-
dc.date.available2012-01-31T16:48:22Z-
dc.date.issued2012-01-31T16:48:22Z-
dc.identifier.citationJSLS. 2011 Jan-Mar;15(1):65-9.en_GB
dc.identifier.issn1086-8089 (Print)en_GB
dc.identifier.issn1086-8089 (Linking)en_GB
dc.identifier.pmid21902946en_GB
dc.identifier.doi10.4293/108680811X13022985131291en_GB
dc.identifier.urihttp://hdl.handle.net/10147/206283-
dc.description.abstractBACKGROUND AND OBJECTIVES: Liver function tests (LFTs) include alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transpeptidase (GGT), alkaline phosphatase (ALP), and bilirubin. The role of routine testing before and after laparoscopic cholecystectomy was evaluated in this study. PATIENTS AND METHODS: A total of 355 patients were retrospectively analyzed by examining the LFTs the day before, the day after, and 3 weeks after the surgery. The Wilcoxon signed-rank test and Student t test were performed to determine statistical significance. RESULTS: Alterations in the serum AST, ALT, and GGT were seen on the first postoperative day. Minor changes were seen in bilirubin and ALP. An overall disturbance in the LFTs was seen in more than two-thirds of the cases. Repeat LFTs performed after 3 weeks on follow-up were found to be within normal limits. CONCLUSION: Mild-to-moderate elevation in preoperative LFTs may not be associated with any deleterious effect, and, in the absence of clinical indications, routine preoperative or postoperative liver function testing is unnecessary.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.mesh*Cholecystectomy, Laparoscopicen_GB
dc.subject.meshDiagnostic Tests, Routineen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshLiver Function Tests/*utilizationen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshPostoperative Care/utilizationen_GB
dc.subject.meshPreoperative Care/utilizationen_GB
dc.subject.meshUnnecessary Procedures/*utilizationen_GB
dc.titleRoutine testing of liver function before and after elective laparoscopic cholecystectomy: is it necessary?en_GB
dc.contributor.departmentMid Western Regional Hospital, Ennis, County Clare, Republic of Ireland., nasirzahmad@gmail.comen_GB
dc.identifier.journalJSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of, Laparoendoscopic Surgeonsen_GB
dc.description.provinceMunster-

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