Gitelman's syndrome in pregnancy: case report and review of the literature.

Hdl Handle:
http://hdl.handle.net/10147/206225
Title:
Gitelman's syndrome in pregnancy: case report and review of the literature.
Authors:
McCarthy, Fergus P; Magee, Ciara N; Plant, William D; Kenny, Louise C
Affiliation:
The ANU Research Centre, Department of Obstetrics and Gynaecology, University, College Cork, Cork University Maternity Hospital, Wilton, Cork., Fergus.mccarthy@ucc.ie
Citation:
Nephrol Dial Transplant. 2010 Apr;25(4):1338-40. Epub 2010 Jan 25.
Journal:
Nephrology, dialysis, transplantation : official publication of the European, Dialysis and Transplant Association - European Renal Association
Issue Date:
31-Jan-2012
URI:
http://hdl.handle.net/10147/206225
DOI:
10.1093/ndt/gfp688
PubMed ID:
20100726
Abstract:
Gitelman's syndrome (GS), a rare renal disorder, results in hypokalaemia, hypomagnesaemia, hypocalciuria and a metabolic alkalosis. It is unclear if an alteration in management is necessary or beneficial during pregnancy. A 32-year-old woman with GS was managed in her second pregnancy. Antenatally, the patient required 39 (principally day case) admissions to the hospital for intravenous (IV) therapy and received a cumulative total of 47 l of IV 0.9% saline solution, 47 doses of 20 mmol magnesium chloride and 46 doses of 80 mmol potassium chloride. She delivered a 2940-g female infant in excellent condition by caesarean section. We would suggest that close attention to maternal weight gain during pregnancy is an easily available clinical tool to assess adequacy of fluid and electrolyte repletion in this condition.
Language:
eng
MeSH:
Adult; Female; Gitelman Syndrome/*complications; Humans; Hypocalcemia/*etiology; Hypokalemia/*diagnosis; Infant; Magnesium Deficiency/*diagnosis; Pregnancy; Prognosis
ISSN:
1460-2385 (Electronic); 0931-0509 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorMcCarthy, Fergus Pen_GB
dc.contributor.authorMagee, Ciara Nen_GB
dc.contributor.authorPlant, William Den_GB
dc.contributor.authorKenny, Louise Cen_GB
dc.date.accessioned2012-01-31T16:42:33Z-
dc.date.available2012-01-31T16:42:33Z-
dc.date.issued2012-01-31T16:42:33Z-
dc.identifier.citationNephrol Dial Transplant. 2010 Apr;25(4):1338-40. Epub 2010 Jan 25.en_GB
dc.identifier.issn1460-2385 (Electronic)en_GB
dc.identifier.issn0931-0509 (Linking)en_GB
dc.identifier.pmid20100726en_GB
dc.identifier.doi10.1093/ndt/gfp688en_GB
dc.identifier.urihttp://hdl.handle.net/10147/206225-
dc.description.abstractGitelman's syndrome (GS), a rare renal disorder, results in hypokalaemia, hypomagnesaemia, hypocalciuria and a metabolic alkalosis. It is unclear if an alteration in management is necessary or beneficial during pregnancy. A 32-year-old woman with GS was managed in her second pregnancy. Antenatally, the patient required 39 (principally day case) admissions to the hospital for intravenous (IV) therapy and received a cumulative total of 47 l of IV 0.9% saline solution, 47 doses of 20 mmol magnesium chloride and 46 doses of 80 mmol potassium chloride. She delivered a 2940-g female infant in excellent condition by caesarean section. We would suggest that close attention to maternal weight gain during pregnancy is an easily available clinical tool to assess adequacy of fluid and electrolyte repletion in this condition.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshFemaleen_GB
dc.subject.meshGitelman Syndrome/*complicationsen_GB
dc.subject.meshHumansen_GB
dc.subject.meshHypocalcemia/*etiologyen_GB
dc.subject.meshHypokalemia/*diagnosisen_GB
dc.subject.meshInfanten_GB
dc.subject.meshMagnesium Deficiency/*diagnosisen_GB
dc.subject.meshPregnancyen_GB
dc.subject.meshPrognosisen_GB
dc.titleGitelman's syndrome in pregnancy: case report and review of the literature.en_GB
dc.contributor.departmentThe ANU Research Centre, Department of Obstetrics and Gynaecology, University, College Cork, Cork University Maternity Hospital, Wilton, Cork., Fergus.mccarthy@ucc.ieen_GB
dc.identifier.journalNephrology, dialysis, transplantation : official publication of the European, Dialysis and Transplant Association - European Renal Associationen_GB
dc.description.provinceMunster-

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