Chronic thromboembolic disease and necrotizing granulomatous vasculitis – A case report

Hdl Handle:
http://hdl.handle.net/10147/201376
Title:
Chronic thromboembolic disease and necrotizing granulomatous vasculitis – A case report
Authors:
Forde, Donall G.; McCullagh, Brian; Henry, Michael T.; Gaine, Sean P.; Murphy, Desmond M.
Citation:
Chronic thromboembolic disease and necrotizing granulomatous vasculitis – A case report 2011, 4 (4):149 Respiratory Medicine CME
Journal:
Respiratory Medicine CME
Issue Date:
2011
URI:
http://hdl.handle.net/10147/201376
DOI:
10.1016/j.rmedc.2011.07.003
Additional Links:
http://linkinghub.elsevier.com/retrieve/pii/S175500171100042X
Item Type:
Article
Language:
en
Description:
A 32 year old male presented to our services with severe, progressive breathlessness. Following a detailed clinical work-up he was found to have severe pulmonary arterial hypertension due to chronic thromboembolic disease. No risk factor for venous thromboembolism,was identified at this time. Vasculitic screen including anti-neutrophil cytoplasmic antibody (ANCA) was normal. He was referred for pulmonary artery endarterectomy which was performed successfully and with good initial improvement in his symptom complex. He represented with breathlessness four months later. He was diagnosed with necrotizing granulomatous vasculitis (known formerly as Wegner's Granulomatosis). While an association between necrotizing granulomatous vasculitis and venous thromboembolic disease is well described, to our knowledge this is the first case of a patient with chronic thromboembolic pulmonary hypertensive disease subsequently developing fulminant necrotizing granulomatous vasculitis.
ISSN:
17550017

Full metadata record

DC FieldValue Language
dc.contributor.authorForde, Donall G.en
dc.contributor.authorMcCullagh, Brianen
dc.contributor.authorHenry, Michael T.en
dc.contributor.authorGaine, Sean P.en
dc.contributor.authorMurphy, Desmond M.en
dc.date.accessioned2012-01-10T16:40:17Z-
dc.date.available2012-01-10T16:40:17Z-
dc.date.issued2011-
dc.identifier.citationChronic thromboembolic disease and necrotizing granulomatous vasculitis – A case report 2011, 4 (4):149 Respiratory Medicine CMEen
dc.identifier.issn17550017-
dc.identifier.doi10.1016/j.rmedc.2011.07.003-
dc.identifier.urihttp://hdl.handle.net/10147/201376-
dc.descriptionA 32 year old male presented to our services with severe, progressive breathlessness. Following a detailed clinical work-up he was found to have severe pulmonary arterial hypertension due to chronic thromboembolic disease. No risk factor for venous thromboembolism,was identified at this time. Vasculitic screen including anti-neutrophil cytoplasmic antibody (ANCA) was normal. He was referred for pulmonary artery endarterectomy which was performed successfully and with good initial improvement in his symptom complex. He represented with breathlessness four months later. He was diagnosed with necrotizing granulomatous vasculitis (known formerly as Wegner's Granulomatosis). While an association between necrotizing granulomatous vasculitis and venous thromboembolic disease is well described, to our knowledge this is the first case of a patient with chronic thromboembolic pulmonary hypertensive disease subsequently developing fulminant necrotizing granulomatous vasculitis.en
dc.language.isoenen
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S175500171100042Xen
dc.titleChronic thromboembolic disease and necrotizing granulomatous vasculitis – A case reporten
dc.typeArticleen
dc.identifier.journalRespiratory Medicine CMEen
dc.description.provinceMunster-
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