EEG in the healthy term newborn within 12 hours of birth.

Hdl Handle:
http://hdl.handle.net/10147/201333
Title:
EEG in the healthy term newborn within 12 hours of birth.
Authors:
Korotchikova, I; Connolly, S; Ryan, C A; Murray, D M; Temko, A; Greene, B R; Boylan, G B
Affiliation:
Department of Paediatrics and Child Health, University College Cork, c/o Clinical Investigation Unit, Cork University Hospital, Wilton, Cork, Ireland. I.Korotchikova@ucc.ie
Citation:
EEG in the healthy term newborn within 12 hours of birth. 2009, 120 (6):1046-53 Clin Neurophysiol
Journal:
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Issue Date:
Jun-2009
URI:
http://hdl.handle.net/10147/201333
DOI:
10.1016/j.clinph.2009.03.015
PubMed ID:
19427811
Abstract:
To characterise and quantify the EEG during sleep in healthy newborns in the early newborn period.; Continuous multi-channel video-EEG data was recorded for up to 2 hours in normal newborns within 12 hours of birth. The total amount of active (AS) and quiet sleep (QS) was calculated in the first hour of recording. The EEG signal was quantitatively analysed for symmetry and synchrony. Spectral edge frequency (SEF), spectral entropy (H) and relative delta power (delta(R)) were calculated for a ten-minute segment of AS and QS in each recording. Paired t-test and Wilcoxon rank sum test were used for data analysis.; Thirty normal newborn babies were studied, 10 within 6 hours of birth and 20 between 6 and 12 hours. All babies showed continuous symmetrical and synchronous EEG activity and well-developed sleep-wake cycling (SWC) with the median percentage of AS--48.5% and QS--36.6%. Quantitative EEG analysis of sleep epochs showed that SEF and H were significantly higher (p<0.0001) and delta(R) was significantly lower (p<0.0001) in AS than in QS.; The normal newborn EEG shows symmetrical and synchronous continuous activity and well-developed SWC as early as within the first 6 hours of birth. Quantitative analysis of the EEG in the early postnatal period reveals differences in SEF, H and delta(R) for AS and QS periods.; These findings may have implications for quantitative analysis of the newborn EEG, including the EEG of babies with hypoxic ischaemic encephalopathy.
Item Type:
Article
Language:
en
Description:
OBJECTIVE: To characterise and quantify the EEG during sleep in healthy newborns in the early newborn period. METHODS: Continuous multi-channel video-EEG data was recorded for up to 2 hours in normal newborns within 12 hours of birth. The total amount of active (AS) and quiet sleep (QS) was calculated in the first hour of recording. The EEG signal was quantitatively analysed for symmetry and synchrony. Spectral edge frequency (SEF), spectral entropy (H) and relative delta power (delta(R)) were calculated for a ten-minute segment of AS and QS in each recording. Paired t-test and Wilcoxon rank sum test were used for data analysis. RESULTS: Thirty normal newborn babies were studied, 10 within 6 hours of birth and 20 between 6 and 12 hours. All babies showed continuous symmetrical and synchronous EEG activity and well-developed sleep-wake cycling (SWC) with the median percentage of AS--48.5% and QS--36.6%. Quantitative EEG analysis of sleep epochs showed that SEF and H were significantly higher (p<0.0001) and delta(R) was significantly lower (p<0.0001) in AS than in QS. CONCLUSION: The normal newborn EEG shows symmetrical and synchronous continuous activity and well-developed SWC as early as within the first 6 hours of birth. Quantitative analysis of the EEG in the early postnatal period reveals differences in SEF, H and delta(R) for AS and QS periods. SIGNIFICANCE: These findings may have implications for quantitative analysis of the newborn EEG, including the EEG of babies with hypoxic ischaemic encephalopathy.
MeSH:
Brain; Delta Rhythm; Electroencephalography; Female; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Male; Prospective Studies; Reference Values; Sleep
ISSN:
1872-8952

Full metadata record

DC FieldValue Language
dc.contributor.authorKorotchikova, Ien
dc.contributor.authorConnolly, Sen
dc.contributor.authorRyan, C Aen
dc.contributor.authorMurray, D Men
dc.contributor.authorTemko, Aen
dc.contributor.authorGreene, B Ren
dc.contributor.authorBoylan, G Ben
dc.date.accessioned2012-01-10T15:31:12Z-
dc.date.available2012-01-10T15:31:12Z-
dc.date.issued2009-06-
dc.identifier.citationEEG in the healthy term newborn within 12 hours of birth. 2009, 120 (6):1046-53 Clin Neurophysiolen
dc.identifier.issn1872-8952-
dc.identifier.pmid19427811-
dc.identifier.doi10.1016/j.clinph.2009.03.015-
dc.identifier.urihttp://hdl.handle.net/10147/201333-
dc.descriptionOBJECTIVE: To characterise and quantify the EEG during sleep in healthy newborns in the early newborn period. METHODS: Continuous multi-channel video-EEG data was recorded for up to 2 hours in normal newborns within 12 hours of birth. The total amount of active (AS) and quiet sleep (QS) was calculated in the first hour of recording. The EEG signal was quantitatively analysed for symmetry and synchrony. Spectral edge frequency (SEF), spectral entropy (H) and relative delta power (delta(R)) were calculated for a ten-minute segment of AS and QS in each recording. Paired t-test and Wilcoxon rank sum test were used for data analysis. RESULTS: Thirty normal newborn babies were studied, 10 within 6 hours of birth and 20 between 6 and 12 hours. All babies showed continuous symmetrical and synchronous EEG activity and well-developed sleep-wake cycling (SWC) with the median percentage of AS--48.5% and QS--36.6%. Quantitative EEG analysis of sleep epochs showed that SEF and H were significantly higher (p<0.0001) and delta(R) was significantly lower (p<0.0001) in AS than in QS. CONCLUSION: The normal newborn EEG shows symmetrical and synchronous continuous activity and well-developed SWC as early as within the first 6 hours of birth. Quantitative analysis of the EEG in the early postnatal period reveals differences in SEF, H and delta(R) for AS and QS periods. SIGNIFICANCE: These findings may have implications for quantitative analysis of the newborn EEG, including the EEG of babies with hypoxic ischaemic encephalopathy.en
dc.description.abstractTo characterise and quantify the EEG during sleep in healthy newborns in the early newborn period.-
dc.description.abstractContinuous multi-channel video-EEG data was recorded for up to 2 hours in normal newborns within 12 hours of birth. The total amount of active (AS) and quiet sleep (QS) was calculated in the first hour of recording. The EEG signal was quantitatively analysed for symmetry and synchrony. Spectral edge frequency (SEF), spectral entropy (H) and relative delta power (delta(R)) were calculated for a ten-minute segment of AS and QS in each recording. Paired t-test and Wilcoxon rank sum test were used for data analysis.-
dc.description.abstractThirty normal newborn babies were studied, 10 within 6 hours of birth and 20 between 6 and 12 hours. All babies showed continuous symmetrical and synchronous EEG activity and well-developed sleep-wake cycling (SWC) with the median percentage of AS--48.5% and QS--36.6%. Quantitative EEG analysis of sleep epochs showed that SEF and H were significantly higher (p<0.0001) and delta(R) was significantly lower (p<0.0001) in AS than in QS.-
dc.description.abstractThe normal newborn EEG shows symmetrical and synchronous continuous activity and well-developed SWC as early as within the first 6 hours of birth. Quantitative analysis of the EEG in the early postnatal period reveals differences in SEF, H and delta(R) for AS and QS periods.-
dc.description.abstractThese findings may have implications for quantitative analysis of the newborn EEG, including the EEG of babies with hypoxic ischaemic encephalopathy.-
dc.language.isoenen
dc.subject.meshBrain-
dc.subject.meshDelta Rhythm-
dc.subject.meshElectroencephalography-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshHypoxia-Ischemia, Brain-
dc.subject.meshInfant, Newborn-
dc.subject.meshMale-
dc.subject.meshProspective Studies-
dc.subject.meshReference Values-
dc.subject.meshSleep-
dc.titleEEG in the healthy term newborn within 12 hours of birth.en
dc.typeArticleen
dc.contributor.departmentDepartment of Paediatrics and Child Health, University College Cork, c/o Clinical Investigation Unit, Cork University Hospital, Wilton, Cork, Ireland. I.Korotchikova@ucc.ieen
dc.identifier.journalClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiologyen
dc.description.provinceMunster-

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