Pouchitis: an evolving clinical enigma--a review.

Hdl Handle:
http://hdl.handle.net/10147/201290
Title:
Pouchitis: an evolving clinical enigma--a review.
Authors:
Coffey, John Calvin; McCarthy, Eoghan; Kavanagh, Eamon; Redmond, Henry Paul; Kirwan, William Oliver
Affiliation:
Department of Academic Surgery, Cork University Hospital, Cork, Ireland. calvincoffey@hotmail.com
Citation:
Pouchitis: an evolving clinical enigma--a review. 2009, 52 (1):140-53 Dis. Colon Rectum
Journal:
Diseases of the colon and rectum
Issue Date:
Jan-2009
URI:
http://hdl.handle.net/10147/201290
DOI:
10.1007/DCR.0b013e31819739d6
PubMed ID:
19273970
Abstract:
While the overall incidence of pouchitis is low, extensive research continues at clinical and experimental levels in attempts to unravel its etiology. The ileal pouch and pouchitis together represent a unique in vivo opportunity to study mucosal adaptation and inflammation in depth. In the recent past, molecular data relating to pouchitis has significantly expanded. These data provide invaluable insight into intracellular and extracellular events that underpin mucosal adaptation and inflammation. Advances in classification, risk factor evaluation, and prevention have meant that a review of this data, as well as its relationship to our current understanding of pouchitis, is both timely and warranted. Therefore, the aim of this review is to summarize recent data in the context of the established literature.
Item Type:
Article
Language:
en
Description:
While the overall incidence of pouchitis is low, extensive research continues at clinical and experimental levels in attempts to unravel its etiology. The ileal pouch and pouchitis together represent a unique in vivo opportunity to study mucosal adaptation and inflammation in depth. In the recent past, molecular data relating to pouchitis has significantly expanded. These data provide invaluable insight into intracellular and extracellular events that underpin mucosal adaptation and inflammation. Advances in classification, risk factor evaluation, and prevention have meant that a review of this data, as well as its relationship to our current understanding of pouchitis, is both timely and warranted. Therefore, the aim of this review is to summarize recent data in the context of the established literature.
MeSH:
Animals; Colonic Pouches; Humans; Pouchitis; Risk Factors
ISSN:
1530-0358

Full metadata record

DC FieldValue Language
dc.contributor.authorCoffey, John Calvinen
dc.contributor.authorMcCarthy, Eoghanen
dc.contributor.authorKavanagh, Eamonen
dc.contributor.authorRedmond, Henry Paulen
dc.contributor.authorKirwan, William Oliveren
dc.date.accessioned2012-01-10T13:03:25Z-
dc.date.available2012-01-10T13:03:25Z-
dc.date.issued2009-01-
dc.identifier.citationPouchitis: an evolving clinical enigma--a review. 2009, 52 (1):140-53 Dis. Colon Rectumen
dc.identifier.issn1530-0358-
dc.identifier.pmid19273970-
dc.identifier.doi10.1007/DCR.0b013e31819739d6-
dc.identifier.urihttp://hdl.handle.net/10147/201290-
dc.descriptionWhile the overall incidence of pouchitis is low, extensive research continues at clinical and experimental levels in attempts to unravel its etiology. The ileal pouch and pouchitis together represent a unique in vivo opportunity to study mucosal adaptation and inflammation in depth. In the recent past, molecular data relating to pouchitis has significantly expanded. These data provide invaluable insight into intracellular and extracellular events that underpin mucosal adaptation and inflammation. Advances in classification, risk factor evaluation, and prevention have meant that a review of this data, as well as its relationship to our current understanding of pouchitis, is both timely and warranted. Therefore, the aim of this review is to summarize recent data in the context of the established literature.en
dc.description.abstractWhile the overall incidence of pouchitis is low, extensive research continues at clinical and experimental levels in attempts to unravel its etiology. The ileal pouch and pouchitis together represent a unique in vivo opportunity to study mucosal adaptation and inflammation in depth. In the recent past, molecular data relating to pouchitis has significantly expanded. These data provide invaluable insight into intracellular and extracellular events that underpin mucosal adaptation and inflammation. Advances in classification, risk factor evaluation, and prevention have meant that a review of this data, as well as its relationship to our current understanding of pouchitis, is both timely and warranted. Therefore, the aim of this review is to summarize recent data in the context of the established literature.-
dc.language.isoenen
dc.subject.meshAnimals-
dc.subject.meshColonic Pouches-
dc.subject.meshHumans-
dc.subject.meshPouchitis-
dc.subject.meshRisk Factors-
dc.titlePouchitis: an evolving clinical enigma--a review.en
dc.typeArticleen
dc.contributor.departmentDepartment of Academic Surgery, Cork University Hospital, Cork, Ireland. calvincoffey@hotmail.comen
dc.identifier.journalDiseases of the colon and rectumen
dc.description.provinceMunster-

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