When pain after surgery doesn't go away...

Hdl Handle:
http://hdl.handle.net/10147/200985
Title:
When pain after surgery doesn't go away...
Authors:
Burke, Siún; Shorten, George D
Affiliation:
Department of Anaesthesia and Intensive Care Medicine, Cork University Hospital, Wilton, Cork, Ireland.
Citation:
When pain after surgery doesn't go away... 2009, 37 (Pt 1):318-22 Biochem. Soc. Trans.
Journal:
Biochemical Society transactions
Issue Date:
Feb-2009
URI:
http://hdl.handle.net/10147/200985
DOI:
10.1042/BST0370318
PubMed ID:
19143655
Abstract:
Chronic post-surgical pain is a common, under-recognized and important clinical problem which affects millions of patients worldwide. It results from a series of neuroplastic changes associated most commonly with peripheral nerve injury at the time of surgery. Predisposing factors include the type of surgery, pre-operative and acute post-operative pain intensity, and probably psychological (e.g. pain-catastrophizing) and genetic factors [e.g. GCH1 (GTP cyclohydrolase 1) haplotype]. Preventive measures which are currently available include selection of a minimally invasive surgical technique and an aggressive multimodal perioperative analgesic regimen. Very promising therapeutic agents which target the sensitization process are currently in development.
Item Type:
Article
Language:
en
Description:
Chronic post-surgical pain is a common, under-recognized and important clinical problem which affects millions of patients worldwide. It results from a series of neuroplastic changes associated most commonly with peripheral nerve injury at the time of surgery. Predisposing factors include the type of surgery, pre-operative and acute post-operative pain intensity, and probably psychological (e.g. pain-catastrophizing) and genetic factors [e.g. GCH1 (GTP cyclohydrolase 1) haplotype]. Preventive measures which are currently available include selection of a minimally invasive surgical technique and an aggressive multimodal perioperative analgesic regimen. Very promising therapeutic agents which target the sensitization process are currently in development.
MeSH:
Animals; Humans; Pain, Postoperative; Patient Education as Topic; Risk Factors
ISSN:
1470-8752

Full metadata record

DC FieldValue Language
dc.contributor.authorBurke, Siúnen
dc.contributor.authorShorten, George Den
dc.date.accessioned2012-01-09T16:48:16Z-
dc.date.available2012-01-09T16:48:16Z-
dc.date.issued2009-02-
dc.identifier.citationWhen pain after surgery doesn't go away... 2009, 37 (Pt 1):318-22 Biochem. Soc. Trans.en
dc.identifier.issn1470-8752-
dc.identifier.pmid19143655-
dc.identifier.doi10.1042/BST0370318-
dc.identifier.urihttp://hdl.handle.net/10147/200985-
dc.descriptionChronic post-surgical pain is a common, under-recognized and important clinical problem which affects millions of patients worldwide. It results from a series of neuroplastic changes associated most commonly with peripheral nerve injury at the time of surgery. Predisposing factors include the type of surgery, pre-operative and acute post-operative pain intensity, and probably psychological (e.g. pain-catastrophizing) and genetic factors [e.g. GCH1 (GTP cyclohydrolase 1) haplotype]. Preventive measures which are currently available include selection of a minimally invasive surgical technique and an aggressive multimodal perioperative analgesic regimen. Very promising therapeutic agents which target the sensitization process are currently in development.en
dc.description.abstractChronic post-surgical pain is a common, under-recognized and important clinical problem which affects millions of patients worldwide. It results from a series of neuroplastic changes associated most commonly with peripheral nerve injury at the time of surgery. Predisposing factors include the type of surgery, pre-operative and acute post-operative pain intensity, and probably psychological (e.g. pain-catastrophizing) and genetic factors [e.g. GCH1 (GTP cyclohydrolase 1) haplotype]. Preventive measures which are currently available include selection of a minimally invasive surgical technique and an aggressive multimodal perioperative analgesic regimen. Very promising therapeutic agents which target the sensitization process are currently in development.-
dc.language.isoenen
dc.subject.meshAnimals-
dc.subject.meshHumans-
dc.subject.meshPain, Postoperative-
dc.subject.meshPatient Education as Topic-
dc.subject.meshRisk Factors-
dc.titleWhen pain after surgery doesn't go away...en
dc.typeArticleen
dc.contributor.departmentDepartment of Anaesthesia and Intensive Care Medicine, Cork University Hospital, Wilton, Cork, Ireland.en
dc.identifier.journalBiochemical Society transactionsen
dc.description.provinceMunster-

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