Lack of correlation between calcium intake and serum calcium levels in stable haemodialysis subjects.

Hdl Handle:
http://hdl.handle.net/10147/200972
Title:
Lack of correlation between calcium intake and serum calcium levels in stable haemodialysis subjects.
Authors:
Byrne, Fiona N; Kinsella, Sinead; Murnaghan, Dermot J; Kiely, Mairead; Eustace, Joseph A
Affiliation:
Department of Nutrition and Dietetics, Cork University Hospital, Cork, Ireland.
Citation:
Lack of correlation between calcium intake and serum calcium levels in stable haemodialysis subjects. 2009, 113 (3):c162-8 Nephron Clin Pract
Publisher:
Karger
Journal:
Nephron. Clinical practice
Issue Date:
2009
URI:
http://hdl.handle.net/10147/200972
DOI:
10.1159/000232597
PubMed ID:
19672114
Abstract:
The relationship between calcium intake and serum calcium level in hemodialysis patients is poorly understood.; We quantify total oral calcium intake using detailed 7-day food diaries with 294 patient days of observation in 42 stable, non-diabetic hemodialysis subjects.; Mean (SD) albumin-corrected serum calcium was 9.84 mg/dl (0.8). The albumin-corrected serum calcium was low (<8.4 mg/dl) in 2 patients, low-normal (8.4-9.49) in 9 patients, high-normal (9.5-10.2) in 18 patients and high (>10.2) in 13 patients. Mean (SD) total (diet plus binder) oral calcium intake was 1996 mg/day (1,020); 16 patients (38%) had a total calcium intake >2,000 mg/day. Calcium intake and serum calcium were poorly correlated (Spearman rank method), r = 0.14, p = 0.39. Median calcium intakes were similar in those with normal (1,990 mg/day), high-normal (1,926 mg/day) and high calcium groups (1,713 mg/day), p = 0.73 (Kruskal-Wallis), p = 0.29 (linear test for trend). Forty-one percent (11/27) of patients who had serum calcium in the normal range had a calcium intake greater than 2 g/day, while 11.5% had a calcium intake greater than 3 g/day. In subjects with a parathyroid hormone (PTH) concentration <300 pg/ml (n = 20), the correlation between calcium intake and either uncorrected serum calcium or albumin-corrected serum calcium was stronger, r = 0.45, p = 0.05 and r = 0.38, p = 0.10, respectively, though there remained wide variability in calcium intake.; Serum calcium is not a reliable indicator of calcium intake, especially at PTH > or = 300 pg/ml. An excessive calcium intake may coexist with a normal serum calcium level.
Item Type:
Article
Language:
en
MeSH:
Adult; Aged; Biological Markers; Calcium; Calcium, Dietary; Female; Humans; Male; Middle Aged; Parathyroid Hormone; Renal Dialysis; Retrospective Studies
ISSN:
1660-2110

Full metadata record

DC FieldValue Language
dc.contributor.authorByrne, Fiona Nen
dc.contributor.authorKinsella, Sineaden
dc.contributor.authorMurnaghan, Dermot Jen
dc.contributor.authorKiely, Maireaden
dc.contributor.authorEustace, Joseph Aen
dc.date.accessioned2012-01-09T15:52:58Z-
dc.date.available2012-01-09T15:52:58Z-
dc.date.issued2009-
dc.identifier.citationLack of correlation between calcium intake and serum calcium levels in stable haemodialysis subjects. 2009, 113 (3):c162-8 Nephron Clin Practen
dc.identifier.issn1660-2110-
dc.identifier.pmid19672114-
dc.identifier.doi10.1159/000232597-
dc.identifier.urihttp://hdl.handle.net/10147/200972-
dc.description.abstractThe relationship between calcium intake and serum calcium level in hemodialysis patients is poorly understood.-
dc.description.abstractWe quantify total oral calcium intake using detailed 7-day food diaries with 294 patient days of observation in 42 stable, non-diabetic hemodialysis subjects.-
dc.description.abstractMean (SD) albumin-corrected serum calcium was 9.84 mg/dl (0.8). The albumin-corrected serum calcium was low (<8.4 mg/dl) in 2 patients, low-normal (8.4-9.49) in 9 patients, high-normal (9.5-10.2) in 18 patients and high (>10.2) in 13 patients. Mean (SD) total (diet plus binder) oral calcium intake was 1996 mg/day (1,020); 16 patients (38%) had a total calcium intake >2,000 mg/day. Calcium intake and serum calcium were poorly correlated (Spearman rank method), r = 0.14, p = 0.39. Median calcium intakes were similar in those with normal (1,990 mg/day), high-normal (1,926 mg/day) and high calcium groups (1,713 mg/day), p = 0.73 (Kruskal-Wallis), p = 0.29 (linear test for trend). Forty-one percent (11/27) of patients who had serum calcium in the normal range had a calcium intake greater than 2 g/day, while 11.5% had a calcium intake greater than 3 g/day. In subjects with a parathyroid hormone (PTH) concentration <300 pg/ml (n = 20), the correlation between calcium intake and either uncorrected serum calcium or albumin-corrected serum calcium was stronger, r = 0.45, p = 0.05 and r = 0.38, p = 0.10, respectively, though there remained wide variability in calcium intake.-
dc.description.abstractSerum calcium is not a reliable indicator of calcium intake, especially at PTH > or = 300 pg/ml. An excessive calcium intake may coexist with a normal serum calcium level.-
dc.language.isoenen
dc.publisherKargeren
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshBiological Markers-
dc.subject.meshCalcium-
dc.subject.meshCalcium, Dietary-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshParathyroid Hormone-
dc.subject.meshRenal Dialysis-
dc.subject.meshRetrospective Studies-
dc.titleLack of correlation between calcium intake and serum calcium levels in stable haemodialysis subjects.en
dc.typeArticleen
dc.contributor.departmentDepartment of Nutrition and Dietetics, Cork University Hospital, Cork, Ireland.en
dc.identifier.journalNephron. Clinical practiceen
dc.description.provinceMunster-

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