Fulminant limb and retroperitoneal necrotizing fasciitis in a 15-year-old girl with Fanconi anaemia.

Hdl Handle:
http://hdl.handle.net/10147/200971
Title:
Fulminant limb and retroperitoneal necrotizing fasciitis in a 15-year-old girl with Fanconi anaemia.
Authors:
O'Regan, Kevin; O'Mahony, Edward; MacEneaney, Peter; Fitzgerald, Edward; Maher, Michael M
Affiliation:
Department of Radiology, Mercy University Hospital, Cork, Republic of Ireland. kevin.oregan@ucc.ie
Citation:
Fulminant limb and retroperitoneal necrotizing fasciitis in a 15-year-old girl with Fanconi anaemia. 2009, 39 (10):1095-7 Pediatr Radiol
Journal:
Pediatric radiology
Issue Date:
Oct-2009
URI:
http://hdl.handle.net/10147/200971
DOI:
10.1007/s00247-009-1324-4
PubMed ID:
19547962
Abstract:
Necrotizing fasciitis (NF) is an uncommon soft-tissue infection in children that carries a high mortality rate. We present a 15-year-old girl with chronic pancytopenia secondary to Fanconi anaemia who developed extensive NF of the lower limb, which unfortunately resulted in a fatal outcome. Immunodeficiency is a known risk factor for the development of this condition. The findings in this case demonstrate that patients with Fanconi anaemia may be susceptible to NF and that the clinical course may be more aggressive due to underlying immunosuppression. Prompt diagnosis of NF is vital in order to initiate appropriate treatment and to optimize patient outcome. Radiological investigation demonstrated extensive soft-tissue gas and destruction affecting the entire lower limb, abdominal wall and retroperitoneum, which led to timely definitive diagnosis and management.
Item Type:
Article
Language:
en
Description:
Necrotizing fasciitis (NF) is an uncommon soft-tissue infection in children that carries a high mortality rate. We present a 15-year-old girl with chronic pancytopenia secondary to Fanconi anaemia who developed extensive NF of the lower limb, which unfortunately resulted in a fatal outcome. Immunodeficiency is a known risk factor for the development of this condition. The findings in this case demonstrate that patients with Fanconi anaemia may be susceptible to NF and that the clinical course may be more aggressive due to underlying immunosuppression. Prompt diagnosis of NF is vital in order to initiate appropriate treatment and to optimize patient outcome. Radiological investigation demonstrated extensive soft-tissue gas and destruction affecting the entire lower limb, abdominal wall and retroperitoneum, which led to timely definitive diagnosis and management.
MeSH:
Adolescent; Fanconi Anemia; Fasciitis, Necrotizing; Fatal Outcome; Female; Humans; Leg; Retroperitoneal Space
ISSN:
1432-1998

Full metadata record

DC FieldValue Language
dc.contributor.authorO'Regan, Kevinen
dc.contributor.authorO'Mahony, Edwarden
dc.contributor.authorMacEneaney, Peteren
dc.contributor.authorFitzgerald, Edwarden
dc.contributor.authorMaher, Michael Men
dc.date.accessioned2012-01-09T15:51:10Z-
dc.date.available2012-01-09T15:51:10Z-
dc.date.issued2009-10-
dc.identifier.citationFulminant limb and retroperitoneal necrotizing fasciitis in a 15-year-old girl with Fanconi anaemia. 2009, 39 (10):1095-7 Pediatr Radiolen
dc.identifier.issn1432-1998-
dc.identifier.pmid19547962-
dc.identifier.doi10.1007/s00247-009-1324-4-
dc.identifier.urihttp://hdl.handle.net/10147/200971-
dc.descriptionNecrotizing fasciitis (NF) is an uncommon soft-tissue infection in children that carries a high mortality rate. We present a 15-year-old girl with chronic pancytopenia secondary to Fanconi anaemia who developed extensive NF of the lower limb, which unfortunately resulted in a fatal outcome. Immunodeficiency is a known risk factor for the development of this condition. The findings in this case demonstrate that patients with Fanconi anaemia may be susceptible to NF and that the clinical course may be more aggressive due to underlying immunosuppression. Prompt diagnosis of NF is vital in order to initiate appropriate treatment and to optimize patient outcome. Radiological investigation demonstrated extensive soft-tissue gas and destruction affecting the entire lower limb, abdominal wall and retroperitoneum, which led to timely definitive diagnosis and management.en
dc.description.abstractNecrotizing fasciitis (NF) is an uncommon soft-tissue infection in children that carries a high mortality rate. We present a 15-year-old girl with chronic pancytopenia secondary to Fanconi anaemia who developed extensive NF of the lower limb, which unfortunately resulted in a fatal outcome. Immunodeficiency is a known risk factor for the development of this condition. The findings in this case demonstrate that patients with Fanconi anaemia may be susceptible to NF and that the clinical course may be more aggressive due to underlying immunosuppression. Prompt diagnosis of NF is vital in order to initiate appropriate treatment and to optimize patient outcome. Radiological investigation demonstrated extensive soft-tissue gas and destruction affecting the entire lower limb, abdominal wall and retroperitoneum, which led to timely definitive diagnosis and management.-
dc.language.isoenen
dc.subject.meshAdolescent-
dc.subject.meshFanconi Anemia-
dc.subject.meshFasciitis, Necrotizing-
dc.subject.meshFatal Outcome-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshLeg-
dc.subject.meshRetroperitoneal Space-
dc.titleFulminant limb and retroperitoneal necrotizing fasciitis in a 15-year-old girl with Fanconi anaemia.en
dc.typeArticleen
dc.contributor.departmentDepartment of Radiology, Mercy University Hospital, Cork, Republic of Ireland. kevin.oregan@ucc.ieen
dc.identifier.journalPediatric radiologyen
dc.description.provinceMunster-

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