Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions.

Hdl Handle:
http://hdl.handle.net/10147/200280
Title:
Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions.
Authors:
Rodríguez-Granillo, Gastón A; Rosales, Miguel A; Renes, Paola; Diez, Eduardo; Pereyra, Jorge; Gomez, Estela; De Lillo, Gustavo; Degrossi, Elina; Rodriguez, Alfredo E; McFadden, Eugene P
Affiliation:
Department of Cardiovascular Imaging, Otamendi Hospital, Azcuenaga 870 (C1115AAB), Buenos Aires, Argentina. grodriguezgranillo@gmail.com
Citation:
Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions., 4 (2):99-107 J Cardiovasc Comput Tomogr
Publisher:
Elsevier
Journal:
Journal of cardiovascular computed tomography
Issue Date:
5-Jan-2012
URI:
http://hdl.handle.net/10147/200280
DOI:
10.1016/j.jcct.2009.12.003
PubMed ID:
20060800
Abstract:
Hypoenhanced regions on multidetector CT (MDCT) coronary angiography correlate with myocardial hyperperfusion. In addition to a limited capillary density, chronic myocardial infarction (MI) commonly contains a considerable amount of adipose tissue.; We explored whether regional myocardial hypoenhancement on contrast-enhanced MDCT could be identified with standard coronary artery calcium (CAC) scoring acquisitions with noncontrast CT.; Consecutive patients with a history of MI who were referred for contrast-enhanced MDCT from November 2006 until March 2009 were studied. Noncontrast CT for CAC scoring was also performed. The correlation between regional myocardial hypoenhancement on contrast-enhanced CT and regional myocardial hypoattenuated areas on noncontrast CT was defined.; Eighty-three patients (mean age, 61.5+/-12.5 years; n=67; 81% male) with previous MI were studied. A total of 1411 myocardial segments were evaluated. Two hundred thirty-nine segments (17%) showed myocardial hypoenhancement by MDCT and 140 segments (9.6%) by CAC. On a patient level, noncontrast CT showed a sensitivity, specificity, positive predictive value, (PPV) and negative predictive value (NPV) of 66% (95% CI, 0.53-0.77), 100% (95% CI, 0.76-1.00), 100% (95% CI, 0.90-1.00), and 41% (95% CI, 0.26-0.58), respectively, to detect myocardial hypoenhancement. On a per segment level, noncontrast CT showed a sensitivity, specificity, PPV, and NPV of 58% (95% CI, 0.51-0.64), 100% (95% CI, 0.99-1.00), 99% (95% CI, 0.94-1.00), and 92% (95% CI, 0.90-0.93), respectively, to detect myocardial hypoenhancement.; Our findings suggest that chronic MI can be detected with standard CAC scoring acquisitions.
Item Type:
Article
Language:
en
MeSH:
Adipose Tissue; Aged; Calcinosis; Chronic Disease; Contrast Media; Coronary Angiography; Coronary Circulation; Coronary Vessels; Female; Heart; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Myocardium; Necrosis; Retrospective Studies; Tomography, X-Ray Computed; Ventricular Function, Left
ISSN:
1876-861X

Full metadata record

DC FieldValue Language
dc.contributor.authorRodríguez-Granillo, Gastón Aen
dc.contributor.authorRosales, Miguel Aen
dc.contributor.authorRenes, Paolaen
dc.contributor.authorDiez, Eduardoen
dc.contributor.authorPereyra, Jorgeen
dc.contributor.authorGomez, Estelaen
dc.contributor.authorDe Lillo, Gustavoen
dc.contributor.authorDegrossi, Elinaen
dc.contributor.authorRodriguez, Alfredo Een
dc.contributor.authorMcFadden, Eugene Pen
dc.date.accessioned2012-01-05T14:51:06Z-
dc.date.available2012-01-05T14:51:06Z-
dc.date.issued2012-01-05T14:51:06Z-
dc.identifier.citationChronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions., 4 (2):99-107 J Cardiovasc Comput Tomogren
dc.identifier.issn1876-861X-
dc.identifier.pmid20060800-
dc.identifier.doi10.1016/j.jcct.2009.12.003-
dc.identifier.urihttp://hdl.handle.net/10147/200280-
dc.description.abstractHypoenhanced regions on multidetector CT (MDCT) coronary angiography correlate with myocardial hyperperfusion. In addition to a limited capillary density, chronic myocardial infarction (MI) commonly contains a considerable amount of adipose tissue.-
dc.description.abstractWe explored whether regional myocardial hypoenhancement on contrast-enhanced MDCT could be identified with standard coronary artery calcium (CAC) scoring acquisitions with noncontrast CT.-
dc.description.abstractConsecutive patients with a history of MI who were referred for contrast-enhanced MDCT from November 2006 until March 2009 were studied. Noncontrast CT for CAC scoring was also performed. The correlation between regional myocardial hypoenhancement on contrast-enhanced CT and regional myocardial hypoattenuated areas on noncontrast CT was defined.-
dc.description.abstractEighty-three patients (mean age, 61.5+/-12.5 years; n=67; 81% male) with previous MI were studied. A total of 1411 myocardial segments were evaluated. Two hundred thirty-nine segments (17%) showed myocardial hypoenhancement by MDCT and 140 segments (9.6%) by CAC. On a patient level, noncontrast CT showed a sensitivity, specificity, positive predictive value, (PPV) and negative predictive value (NPV) of 66% (95% CI, 0.53-0.77), 100% (95% CI, 0.76-1.00), 100% (95% CI, 0.90-1.00), and 41% (95% CI, 0.26-0.58), respectively, to detect myocardial hypoenhancement. On a per segment level, noncontrast CT showed a sensitivity, specificity, PPV, and NPV of 58% (95% CI, 0.51-0.64), 100% (95% CI, 0.99-1.00), 99% (95% CI, 0.94-1.00), and 92% (95% CI, 0.90-0.93), respectively, to detect myocardial hypoenhancement.-
dc.description.abstractOur findings suggest that chronic MI can be detected with standard CAC scoring acquisitions.-
dc.language.isoenen
dc.publisherElsevieren
dc.subject.meshAdipose Tissue-
dc.subject.meshAged-
dc.subject.meshCalcinosis-
dc.subject.meshChronic Disease-
dc.subject.meshContrast Media-
dc.subject.meshCoronary Angiography-
dc.subject.meshCoronary Circulation-
dc.subject.meshCoronary Vessels-
dc.subject.meshFemale-
dc.subject.meshHeart-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshMyocardial Infarction-
dc.subject.meshMyocardial Revascularization-
dc.subject.meshMyocardium-
dc.subject.meshNecrosis-
dc.subject.meshRetrospective Studies-
dc.subject.meshTomography, X-Ray Computed-
dc.subject.meshVentricular Function, Left-
dc.titleChronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions.en
dc.typeArticleen
dc.contributor.departmentDepartment of Cardiovascular Imaging, Otamendi Hospital, Azcuenaga 870 (C1115AAB), Buenos Aires, Argentina. grodriguezgranillo@gmail.comen
dc.identifier.journalJournal of cardiovascular computed tomographyen
dc.description.provinceMunster-

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