Multiple sclerosis exceptionally presenting as parkinsonism responds to intravenous methylprednisolone.

Hdl Handle:
http://hdl.handle.net/10147/200272
Title:
Multiple sclerosis exceptionally presenting as parkinsonism responds to intravenous methylprednisolone.
Authors:
Saidha, S; Mok, T H; Butler, M; Fanning, N; Harrington, H
Affiliation:
Department of Neurology, Mercy University Hospital, Grenville Place, Cork, Ireland. shivsaidha@physicians.ie <shivsaidha@physicians.ie>
Citation:
Multiple sclerosis exceptionally presenting as parkinsonism responds to intravenous methylprednisolone. 2010, 17 (5):654-5 J Clin Neurosci
Journal:
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Issue Date:
May-2010
URI:
http://hdl.handle.net/10147/200272
DOI:
10.1016/j.jocn.2009.09.026
PubMed ID:
20219377
Abstract:
Parkinsonism due to multiple sclerosis (MS) is rare. In previously reported patients with MS-induced parkinsonism, MS manifested first, followed a typical clinical course, and parkinsonism developed later in the course of the illness. We report a 52-year-old male presenting with parkinsonism as the initial manifestation of MS, in whom a subsequent MS relapse consisted of marked deterioration in parkinsonism, a clinical pattern not previously described in MS. A brain MRI demonstrated involvement of the substantia nigra and basal ganglia. This patient illustrates that the clinical presentation and progression of MS may rarely be characterised by predominating parkinsonian features which are reversible by treatment with intravenous methylprednisolone and interferon beta1a.
Item Type:
Article
Language:
en
MeSH:
Disease Progression; Glucocorticoids; Humans; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Multiple Sclerosis; Parkinsonian Disorders; Treatment Outcome
ISSN:
1532-2653

Full metadata record

DC FieldValue Language
dc.contributor.authorSaidha, Sen
dc.contributor.authorMok, T Hen
dc.contributor.authorButler, Men
dc.contributor.authorFanning, Nen
dc.contributor.authorHarrington, Hen
dc.date.accessioned2012-01-05T14:04:30Z-
dc.date.available2012-01-05T14:04:30Z-
dc.date.issued2010-05-
dc.identifier.citationMultiple sclerosis exceptionally presenting as parkinsonism responds to intravenous methylprednisolone. 2010, 17 (5):654-5 J Clin Neuroscien
dc.identifier.issn1532-2653-
dc.identifier.pmid20219377-
dc.identifier.doi10.1016/j.jocn.2009.09.026-
dc.identifier.urihttp://hdl.handle.net/10147/200272-
dc.description.abstractParkinsonism due to multiple sclerosis (MS) is rare. In previously reported patients with MS-induced parkinsonism, MS manifested first, followed a typical clinical course, and parkinsonism developed later in the course of the illness. We report a 52-year-old male presenting with parkinsonism as the initial manifestation of MS, in whom a subsequent MS relapse consisted of marked deterioration in parkinsonism, a clinical pattern not previously described in MS. A brain MRI demonstrated involvement of the substantia nigra and basal ganglia. This patient illustrates that the clinical presentation and progression of MS may rarely be characterised by predominating parkinsonian features which are reversible by treatment with intravenous methylprednisolone and interferon beta1a.-
dc.language.isoenen
dc.subject.meshDisease Progression-
dc.subject.meshGlucocorticoids-
dc.subject.meshHumans-
dc.subject.meshMagnetic Resonance Imaging-
dc.subject.meshMale-
dc.subject.meshMethylprednisolone-
dc.subject.meshMiddle Aged-
dc.subject.meshMultiple Sclerosis-
dc.subject.meshParkinsonian Disorders-
dc.subject.meshTreatment Outcome-
dc.titleMultiple sclerosis exceptionally presenting as parkinsonism responds to intravenous methylprednisolone.en
dc.typeArticleen
dc.contributor.departmentDepartment of Neurology, Mercy University Hospital, Grenville Place, Cork, Ireland. shivsaidha@physicians.ie <shivsaidha@physicians.ie>en
dc.identifier.journalJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasiaen
dc.description.provinceMunster-

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