Maintenance hemodialysis patients have high cumulative radiation exposure.

Hdl Handle:
http://hdl.handle.net/10147/200253
Title:
Maintenance hemodialysis patients have high cumulative radiation exposure.
Authors:
Kinsella, Sinead M; Coyle, Joe P; Long, Eva B; McWilliams, Sebastian R; Maher, Michael M; Clarkson, Michael R; Eustace, Joseph A
Affiliation:
Department of Nephrology, Cork University Hospital, Wilton, Cork, Ireland.
Citation:
Maintenance hemodialysis patients have high cumulative radiation exposure. 2010, 78 (8):789-93 Kidney Int.
Journal:
Kidney international
Issue Date:
Oct-2010
URI:
http://hdl.handle.net/10147/200253
DOI:
10.1038/ki.2010.196
PubMed ID:
20592715
Abstract:
Hemodialysis is associated with an increased risk of neoplasms which may result, at least in part, from exposure to ionizing radiation associated with frequent radiographic procedures. In order to estimate the average radiation exposure of those on hemodialysis, we conducted a retrospective study of 100 patients in a university-based dialysis unit followed for a median of 3.4 years. The number and type of radiological procedures were obtained from a central radiology database, and the cumulative effective radiation dose was calculated using standardized, procedure-specific radiation levels. The median annual radiation dose was 6.9 millisieverts (mSv) per patient-year. However, 14 patients had an annual cumulative effective radiation dose over 20 mSv, the upper averaged annual limit for occupational exposure. The median total cumulative effective radiation dose per patient over the study period was 21.7 mSv, in which 13 patients had a total cumulative effective radiation dose over 75 mSv, a value reported to be associated with a 7% increased risk of cancer-related mortality. Two-thirds of the total cumulative effective radiation dose was due to CT scanning. The average radiation exposure was significantly associated with the cause of end-stage renal disease, history of ischemic heart disease, transplant waitlist status, number of in-patient hospital days over follow-up, and death during the study period. These results highlight the substantial exposure to ionizing radiation in hemodialysis patients.
Item Type:
Article
Language:
en
Description:
Hemodialysis is associated with an increased risk of neoplasms which may result, at least in part, from exposure to ionizing radiation associated with frequent radiographic procedures. In order to estimate the average radiation exposure of those on hemodialysis, we conducted a retrospective study of 100 patients in a university-based dialysis unit followed for a median of 3.4 years. The number and type of radiological procedures were obtained from a central radiology database, and the cumulative effective radiation dose was calculated using standardized, procedure-specific radiation levels. The median annual radiation dose was 6.9 millisieverts (mSv) per patient-year. However, 14 patients had an annual cumulative effective radiation dose over 20 mSv, the upper averaged annual limit for occupational exposure. The median total cumulative effective radiation dose per patient over the study period was 21.7 mSv, in which 13 patients had a total cumulative effective radiation dose over 75 mSv, a value reported to be associated with a 7% increased risk of cancer-related mortality. Two-thirds of the total cumulative effective radiation dose was due to CT scanning. The average radiation exposure was significantly associated with the cause of end-stage renal disease, history of ischemic heart disease, transplant waitlist status, number of in-patient hospital days over follow-up, and death during the study period. These results highlight the substantial exposure to ionizing radiation in hemodialysis patients.
MeSH:
Adult; Aged; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Radiation Dosage; Radiation, Ionizing; Radiography; Retrospective Studies; Risk Assessment; Risk Factors; Tomography, X-Ray Computed; Treatment Outcome
ISSN:
1523-1755

Full metadata record

DC FieldValue Language
dc.contributor.authorKinsella, Sinead Men
dc.contributor.authorCoyle, Joe Pen
dc.contributor.authorLong, Eva Ben
dc.contributor.authorMcWilliams, Sebastian Ren
dc.contributor.authorMaher, Michael Men
dc.contributor.authorClarkson, Michael Ren
dc.contributor.authorEustace, Joseph Aen
dc.date.accessioned2012-01-05T12:01:17Z-
dc.date.available2012-01-05T12:01:17Z-
dc.date.issued2010-10-
dc.identifier.citationMaintenance hemodialysis patients have high cumulative radiation exposure. 2010, 78 (8):789-93 Kidney Int.en
dc.identifier.issn1523-1755-
dc.identifier.pmid20592715-
dc.identifier.doi10.1038/ki.2010.196-
dc.identifier.urihttp://hdl.handle.net/10147/200253-
dc.descriptionHemodialysis is associated with an increased risk of neoplasms which may result, at least in part, from exposure to ionizing radiation associated with frequent radiographic procedures. In order to estimate the average radiation exposure of those on hemodialysis, we conducted a retrospective study of 100 patients in a university-based dialysis unit followed for a median of 3.4 years. The number and type of radiological procedures were obtained from a central radiology database, and the cumulative effective radiation dose was calculated using standardized, procedure-specific radiation levels. The median annual radiation dose was 6.9 millisieverts (mSv) per patient-year. However, 14 patients had an annual cumulative effective radiation dose over 20 mSv, the upper averaged annual limit for occupational exposure. The median total cumulative effective radiation dose per patient over the study period was 21.7 mSv, in which 13 patients had a total cumulative effective radiation dose over 75 mSv, a value reported to be associated with a 7% increased risk of cancer-related mortality. Two-thirds of the total cumulative effective radiation dose was due to CT scanning. The average radiation exposure was significantly associated with the cause of end-stage renal disease, history of ischemic heart disease, transplant waitlist status, number of in-patient hospital days over follow-up, and death during the study period. These results highlight the substantial exposure to ionizing radiation in hemodialysis patients.en
dc.description.abstractHemodialysis is associated with an increased risk of neoplasms which may result, at least in part, from exposure to ionizing radiation associated with frequent radiographic procedures. In order to estimate the average radiation exposure of those on hemodialysis, we conducted a retrospective study of 100 patients in a university-based dialysis unit followed for a median of 3.4 years. The number and type of radiological procedures were obtained from a central radiology database, and the cumulative effective radiation dose was calculated using standardized, procedure-specific radiation levels. The median annual radiation dose was 6.9 millisieverts (mSv) per patient-year. However, 14 patients had an annual cumulative effective radiation dose over 20 mSv, the upper averaged annual limit for occupational exposure. The median total cumulative effective radiation dose per patient over the study period was 21.7 mSv, in which 13 patients had a total cumulative effective radiation dose over 75 mSv, a value reported to be associated with a 7% increased risk of cancer-related mortality. Two-thirds of the total cumulative effective radiation dose was due to CT scanning. The average radiation exposure was significantly associated with the cause of end-stage renal disease, history of ischemic heart disease, transplant waitlist status, number of in-patient hospital days over follow-up, and death during the study period. These results highlight the substantial exposure to ionizing radiation in hemodialysis patients.-
dc.language.isoenen
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshKidney Failure, Chronic-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshRadiation Dosage-
dc.subject.meshRadiation, Ionizing-
dc.subject.meshRadiography-
dc.subject.meshRetrospective Studies-
dc.subject.meshRisk Assessment-
dc.subject.meshRisk Factors-
dc.subject.meshTomography, X-Ray Computed-
dc.subject.meshTreatment Outcome-
dc.titleMaintenance hemodialysis patients have high cumulative radiation exposure.en
dc.typeArticleen
dc.contributor.departmentDepartment of Nephrology, Cork University Hospital, Wilton, Cork, Ireland.en
dc.identifier.journalKidney internationalen
dc.description.provinceMunster-

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