Effects of current size, postnatal growth, and birth size on blood pressure in early childhood

Hdl Handle:
http://hdl.handle.net/10147/189980
Title:
Effects of current size, postnatal growth, and birth size on blood pressure in early childhood
Authors:
Hindmarsh, P. C.; Bryan, S.; Geary, M. P. P.; Cole, T. J.
Citation:
Effects of current size, postnatal growth, and birth size on blood pressure in early childhood 2010, 126 (6):e1507 PEDIATRICS
Journal:
PEDIATRICS
Issue Date:
Nov-2010
URI:
http://hdl.handle.net/10147/189980
DOI:
10.1542/peds.2010-0358
Additional Links:
http://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2010-0358
Item Type:
Article
Language:
en
Description:
Objective: In a prospective study, we investigated the impact of early growth on blood pressure at 3 years of age. Methods: We measured systolic blood pressure (SBP) and diastolic blood pressure (DBP) for 590 children 3 years of age and related measurements to current size and size at birth, 6 months, 1 year, and 2 years of age. Results: SBP was related positively to weight at 3 and 2 years and, after adjustment for current size, negatively to weight at birth and 6 months but not at 1 or 2 years. No effect was observed for DBP. A family history of hypertension was associated with higher maternal blood pressure, greater weight, and gestational hypertension (P = .05). Mothers with a history of gestational hypertension had higher SBP and DBP values (P < .001). In multivariate linear regression analyses, SBP was influenced positively by weight at 3 years and family history of hypertension and negatively by weight at 6 months. None of the factors was associated with DBP. Conclusions: For 3-year-old children, current weight was a determinant of SBP and postnatal growth to 6 months of age was more predictive than birth weight. A family history of hypertension is important in determining maternal blood pressure. These observations suggest a window in which postnatal growth might be modified.
ISSN:
0031-4005; 1098-4275

Full metadata record

DC FieldValue Language
dc.contributor.authorHindmarsh, P. C.en
dc.contributor.authorBryan, S.en
dc.contributor.authorGeary, M. P. P.en
dc.contributor.authorCole, T. J.en
dc.date.accessioned2011-11-18T15:28:14Z-
dc.date.available2011-11-18T15:28:14Z-
dc.date.issued2010-11-
dc.identifier.citationEffects of current size, postnatal growth, and birth size on blood pressure in early childhood 2010, 126 (6):e1507 PEDIATRICSen
dc.identifier.issn0031-4005-
dc.identifier.issn1098-4275-
dc.identifier.doi10.1542/peds.2010-0358-
dc.identifier.urihttp://hdl.handle.net/10147/189980-
dc.descriptionObjective: In a prospective study, we investigated the impact of early growth on blood pressure at 3 years of age. Methods: We measured systolic blood pressure (SBP) and diastolic blood pressure (DBP) for 590 children 3 years of age and related measurements to current size and size at birth, 6 months, 1 year, and 2 years of age. Results: SBP was related positively to weight at 3 and 2 years and, after adjustment for current size, negatively to weight at birth and 6 months but not at 1 or 2 years. No effect was observed for DBP. A family history of hypertension was associated with higher maternal blood pressure, greater weight, and gestational hypertension (P = .05). Mothers with a history of gestational hypertension had higher SBP and DBP values (P < .001). In multivariate linear regression analyses, SBP was influenced positively by weight at 3 years and family history of hypertension and negatively by weight at 6 months. None of the factors was associated with DBP. Conclusions: For 3-year-old children, current weight was a determinant of SBP and postnatal growth to 6 months of age was more predictive than birth weight. A family history of hypertension is important in determining maternal blood pressure. These observations suggest a window in which postnatal growth might be modified.en
dc.language.isoenen
dc.relation.urlhttp://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2010-0358en
dc.titleEffects of current size, postnatal growth, and birth size on blood pressure in early childhooden
dc.typeArticleen
dc.identifier.journalPEDIATRICSen
dc.description.provinceLeinster-
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