Long-term results of an obesity program in an ethnically diverse pediatric population.

Hdl Handle:
http://hdl.handle.net/10147/188294
Title:
Long-term results of an obesity program in an ethnically diverse pediatric population.
Authors:
Savoye, Mary; Nowicka, Paulina; Shaw, Melissa; Yu, Sunkyung; Dziura, James; Chavent, Georgia; O'Malley, Grace; Serrecchia, John B; Tamborlane, William V; Caprio, Sonia
Affiliation:
Yale University School of Medicine, Pediatric Endocrinology, PO Box 208064, New Haven, CT 06520-8064, USA. mary.savoye@yale.edu
Citation:
Long-term results of an obesity program in an ethnically diverse pediatric population. 2011, 127 (3):402-10 Pediatrics
Journal:
Pediatrics
Issue Date:
Mar-2011
URI:
http://hdl.handle.net/10147/188294
DOI:
10.1542/peds.2010-0697
PubMed ID:
21300674
Additional Links:
http://www.ncbi.nlm.nih.gov/pubmed/21300674
Abstract:
To determine if beneficial effects of a weight-management program could be sustained for up to 24 months in a randomized trial in an ethnically diverse obese population.; There were 209 obese children (BMI > 95th percentile), ages 8 to 16 of mixed ethnic backgrounds randomly assigned to the intensive lifestyle intervention or clinic control group. The control group received counseling every 6 months, and the intervention group received a family-based program, which included exercise, nutrition, and behavior modification. Lifestyle intervention sessions occurred twice weekly for the first 6 months, then twice monthly for the second 6 months; for the last 12 months there was no active intervention. There were 174 children who completed the 12 months of the randomized trial. Follow-up data were available for 76 of these children at 24 months. There were no statistical differences in dropout rates among ethnic groups or in any other aspects.; Treatment effect was sustained at 24 months in the intervention versus control group for BMI z score (-0.16 [95% confidence interval: -0.23 to -0.09]), BMI (-2.8 kg/m(2) [95% confidence interval: -4.0-1.6 kg/m(2)]), percent body fat (-4.2% [95% confidence interval: -6.4% to -2.0%]), total body fat mass (-5.8 kg [95% confidence interval: -9.1 kg to -2.6 kg]), total cholesterol (-13.0 mg/dL [95% confidence interval: -21.7 mg/dL to -4.2 mg/dL]), low-density lipoprotein cholesterol (-10.4 mg/dL [95% confidence interval: -18.3 mg/dL to -2.4 mg/dL]), and homeostasis model assessment of insulin resistance (-2.05 [95% confidence interval: -2.48 to -1.75]).; This study, unprecedented because of the high degree of obesity and ethnically diverse backgrounds of children, reveals that benefits of an intensive lifestyle program can be sustained 12 months after completing the active intervention phase.
Item Type:
Article In Press
Language:
en
MeSH:
Adolescent; Behavior Therapy; Body Mass Index; Child; Counseling; Diet, Reducing; Ethnic Groups; Exercise Therapy; Follow-Up Studies; Humans; Obesity; Retrospective Studies; Time Factors; Treatment Outcome; Weight Loss
ISSN:
1098-4275
Sponsors:
Irish Fulbright Commission

Full metadata record

DC FieldValue Language
dc.contributor.authorSavoye, Maryen
dc.contributor.authorNowicka, Paulinaen
dc.contributor.authorShaw, Melissaen
dc.contributor.authorYu, Sunkyungen
dc.contributor.authorDziura, Jamesen
dc.contributor.authorChavent, Georgiaen
dc.contributor.authorO'Malley, Graceen
dc.contributor.authorSerrecchia, John Ben
dc.contributor.authorTamborlane, William Ven
dc.contributor.authorCaprio, Soniaen
dc.date.accessioned2011-11-01T11:53:47Z-
dc.date.available2011-11-01T11:53:47Z-
dc.date.issued2011-03-
dc.identifier.citationLong-term results of an obesity program in an ethnically diverse pediatric population. 2011, 127 (3):402-10 Pediatricsen
dc.identifier.issn1098-4275-
dc.identifier.pmid21300674-
dc.identifier.doi10.1542/peds.2010-0697-
dc.identifier.urihttp://hdl.handle.net/10147/188294-
dc.description.abstractTo determine if beneficial effects of a weight-management program could be sustained for up to 24 months in a randomized trial in an ethnically diverse obese population.-
dc.description.abstractThere were 209 obese children (BMI > 95th percentile), ages 8 to 16 of mixed ethnic backgrounds randomly assigned to the intensive lifestyle intervention or clinic control group. The control group received counseling every 6 months, and the intervention group received a family-based program, which included exercise, nutrition, and behavior modification. Lifestyle intervention sessions occurred twice weekly for the first 6 months, then twice monthly for the second 6 months; for the last 12 months there was no active intervention. There were 174 children who completed the 12 months of the randomized trial. Follow-up data were available for 76 of these children at 24 months. There were no statistical differences in dropout rates among ethnic groups or in any other aspects.-
dc.description.abstractTreatment effect was sustained at 24 months in the intervention versus control group for BMI z score (-0.16 [95% confidence interval: -0.23 to -0.09]), BMI (-2.8 kg/m(2) [95% confidence interval: -4.0-1.6 kg/m(2)]), percent body fat (-4.2% [95% confidence interval: -6.4% to -2.0%]), total body fat mass (-5.8 kg [95% confidence interval: -9.1 kg to -2.6 kg]), total cholesterol (-13.0 mg/dL [95% confidence interval: -21.7 mg/dL to -4.2 mg/dL]), low-density lipoprotein cholesterol (-10.4 mg/dL [95% confidence interval: -18.3 mg/dL to -2.4 mg/dL]), and homeostasis model assessment of insulin resistance (-2.05 [95% confidence interval: -2.48 to -1.75]).-
dc.description.abstractThis study, unprecedented because of the high degree of obesity and ethnically diverse backgrounds of children, reveals that benefits of an intensive lifestyle program can be sustained 12 months after completing the active intervention phase.-
dc.description.sponsorshipIrish Fulbright Commissionen
dc.language.isoenen
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/21300674en
dc.subject.meshAdolescent-
dc.subject.meshBehavior Therapy-
dc.subject.meshBody Mass Index-
dc.subject.meshChild-
dc.subject.meshCounseling-
dc.subject.meshDiet, Reducing-
dc.subject.meshEthnic Groups-
dc.subject.meshExercise Therapy-
dc.subject.meshFollow-Up Studies-
dc.subject.meshHumans-
dc.subject.meshObesity-
dc.subject.meshRetrospective Studies-
dc.subject.meshTime Factors-
dc.subject.meshTreatment Outcome-
dc.subject.meshWeight Loss-
dc.titleLong-term results of an obesity program in an ethnically diverse pediatric population.en
dc.typeArticle In Pressen
dc.contributor.departmentYale University School of Medicine, Pediatric Endocrinology, PO Box 208064, New Haven, CT 06520-8064, USA. mary.savoye@yale.eduen
dc.identifier.journalPediatricsen
dc.description.provinceLeinster-

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