Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database.

Hdl Handle:
http://hdl.handle.net/10147/146382
Title:
Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database.
Authors:
Sokka, T; Kautiainen, H; Pincus, T; Toloza, S; da Rocha Castelar Pinheiro, G; Lazovskis, J; Hetland, M L; Peets, T; Immonen, K; Maillefert, J F; Drosos, A A; Alten, R; Pohl, C; Rojkovich, B; Bresnihan, B; Minnock, P; Cazzato, M; Bombardieri, S; Rexhepi, S; Rexhepi, M; Andersone, D; Stropuviene, S; Huisman, M; Sierakowski, S; Karateev, D; Skakic, V; Naranjo, A; Baecklund, E; Henrohn, D; Gogus, F; Badsha, H; Mofti, A; Taylor, P; McClinton, C; Yazici, Y
Affiliation:
Jyväskylä Central Hospital, 40620 Jyväskylä, Finland. tuulikki.sokka@ksshp.fi
Citation:
Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database. 2009, 68 (11):1666-72 Ann. Rheum. Dis.
Journal:
Annals of the rheumatic diseases
Issue Date:
Nov-2009
URI:
http://hdl.handle.net/10147/146382
DOI:
10.1136/ard.2009.109983
PubMed ID:
19643759
Abstract:
To analyse associations between the clinical status of patients with rheumatoid arthritis (RA) and the gross domestic product (GDP) of their resident country.; The Quantitative Standard Monitoring of Patients with Rheumatoid Arthritis (QUEST-RA) cohort includes clinical and questionnaire data from 6004 patients who were seen in usual care at 70 rheumatology clinics in 25 countries as of April 2008, including 18 European countries. Demographic variables, clinical characteristics, RA disease activity measures, including the disease activity score in 28 joints (DAS28), and treatment-related variables were analysed according to GDP per capita, including 14 "high GDP" countries with GDP per capita greater than US$24,000 and 11 "low GDP" countries with GDP per capita less than US$11,000.; Disease activity DAS28 ranged between 3.1 and 6.0 among the 25 countries and was significantly associated with GDP (r = -0.78, 95% CI -0.56 to -0.90, r(2) = 61%). Disease activity levels differed substantially between "high GDP" and "low GDP" countries at much greater levels than according to whether patients were currently taking or not taking methotrexate, prednisone and/or biological agents.; The clinical status of patients with RA was correlated significantly with GDP among 25 mostly European countries according to all disease measures, associated only modestly with the current use of antirheumatic medications. The burden of arthritis appears substantially greater in "low GDP" than in "high GDP" countries. These findings may alert healthcare professionals and designers of health policy towards improving the clinical status of patients with RA in all countries.
Item Type:
Article
Language:
en
MeSH:
Antirheumatic Agents; Arthritis, Rheumatoid; Cost of Illness; Epidemiologic Methods; Female; Health Status Disparities; Humans; Male; Middle Aged; Socioeconomic Factors; World Health
ISSN:
1468-2060

Full metadata record

DC FieldValue Language
dc.contributor.authorSokka, Ten
dc.contributor.authorKautiainen, Hen
dc.contributor.authorPincus, Ten
dc.contributor.authorToloza, Sen
dc.contributor.authorda Rocha Castelar Pinheiro, Gen
dc.contributor.authorLazovskis, Jen
dc.contributor.authorHetland, M Len
dc.contributor.authorPeets, Ten
dc.contributor.authorImmonen, Ken
dc.contributor.authorMaillefert, J Fen
dc.contributor.authorDrosos, A Aen
dc.contributor.authorAlten, Ren
dc.contributor.authorPohl, Cen
dc.contributor.authorRojkovich, Ben
dc.contributor.authorBresnihan, Ben
dc.contributor.authorMinnock, Pen
dc.contributor.authorCazzato, Men
dc.contributor.authorBombardieri, Sen
dc.contributor.authorRexhepi, Sen
dc.contributor.authorRexhepi, Men
dc.contributor.authorAndersone, Den
dc.contributor.authorStropuviene, Sen
dc.contributor.authorHuisman, Men
dc.contributor.authorSierakowski, Sen
dc.contributor.authorKarateev, Den
dc.contributor.authorSkakic, Ven
dc.contributor.authorNaranjo, Aen
dc.contributor.authorBaecklund, Een
dc.contributor.authorHenrohn, Den
dc.contributor.authorGogus, Fen
dc.contributor.authorBadsha, Hen
dc.contributor.authorMofti, Aen
dc.contributor.authorTaylor, Pen
dc.contributor.authorMcClinton, Cen
dc.contributor.authorYazici, Yen
dc.date.accessioned2011-10-21T13:54:28Z-
dc.date.available2011-10-21T13:54:28Z-
dc.date.issued2009-11-
dc.identifier.citationDisparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database. 2009, 68 (11):1666-72 Ann. Rheum. Dis.en
dc.identifier.issn1468-2060-
dc.identifier.pmid19643759-
dc.identifier.doi10.1136/ard.2009.109983-
dc.identifier.urihttp://hdl.handle.net/10147/146382-
dc.description.abstractTo analyse associations between the clinical status of patients with rheumatoid arthritis (RA) and the gross domestic product (GDP) of their resident country.-
dc.description.abstractThe Quantitative Standard Monitoring of Patients with Rheumatoid Arthritis (QUEST-RA) cohort includes clinical and questionnaire data from 6004 patients who were seen in usual care at 70 rheumatology clinics in 25 countries as of April 2008, including 18 European countries. Demographic variables, clinical characteristics, RA disease activity measures, including the disease activity score in 28 joints (DAS28), and treatment-related variables were analysed according to GDP per capita, including 14 "high GDP" countries with GDP per capita greater than US$24,000 and 11 "low GDP" countries with GDP per capita less than US$11,000.-
dc.description.abstractDisease activity DAS28 ranged between 3.1 and 6.0 among the 25 countries and was significantly associated with GDP (r = -0.78, 95% CI -0.56 to -0.90, r(2) = 61%). Disease activity levels differed substantially between "high GDP" and "low GDP" countries at much greater levels than according to whether patients were currently taking or not taking methotrexate, prednisone and/or biological agents.-
dc.description.abstractThe clinical status of patients with RA was correlated significantly with GDP among 25 mostly European countries according to all disease measures, associated only modestly with the current use of antirheumatic medications. The burden of arthritis appears substantially greater in "low GDP" than in "high GDP" countries. These findings may alert healthcare professionals and designers of health policy towards improving the clinical status of patients with RA in all countries.-
dc.language.isoenen
dc.subject.meshAntirheumatic Agents-
dc.subject.meshArthritis, Rheumatoid-
dc.subject.meshCost of Illness-
dc.subject.meshEpidemiologic Methods-
dc.subject.meshFemale-
dc.subject.meshHealth Status Disparities-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshSocioeconomic Factors-
dc.subject.meshWorld Health-
dc.titleDisparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database.en
dc.typeArticleen
dc.contributor.departmentJyväskylä Central Hospital, 40620 Jyväskylä, Finland. tuulikki.sokka@ksshp.fien
dc.identifier.journalAnnals of the rheumatic diseasesen

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