Disease outcome for children who present with oral manifestations of Crohn's disease.

Hdl Handle:
http://hdl.handle.net/10147/139289
Title:
Disease outcome for children who present with oral manifestations of Crohn's disease.
Authors:
Hussey, S; Fleming, P; Rowland, M; Harty, S; Chan, L; Broderick, A; Drumm, B; Bourke, B
Affiliation:
Dublin Dental University Hospital, Trinity College Dublin, Dublin 2, Ireland.
Citation:
Disease outcome for children who present with oral manifestations of Crohn's disease. 2011, 12 (3):167-9 Eur Arch Paediatr Dent
Journal:
European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry
Issue Date:
Jun-2011
URI:
http://hdl.handle.net/10147/139289
PubMed ID:
21640063
Additional Links:
http://www.ncbi.nlm.nih.gov/pubmed/21640063
Abstract:
To describe the outcome for children with oral Crohn's disease (OCD) at diagnosis, and to determine if there was a difference in the Paediatric Crohn's Disease Activity Index (PCDAI) scores between those with and those without oral lesions at follow-up.; Thirty-one patients with OCD who had enrolled in two previous studies were invited to participate. Clinical and laboratory data were collected to calculate the PCDAI. Details of the management of Crohn's disease were also recorded.; Twenty-four of 31 patients participated (77%), of whom 17 were boys (M:F = 2.4:1). Mean age at follow-up was 15.7 years (SD 1.98, range 11.9-19.7 years). Mean duration of follow-up was 55 months (SD 22, range 20-97 months). Oral manifestations were present at follow-up in 7 (29%) of 24 patients. There were no differences between patients with and without OCD at follow-up with regard to medical treatments received or intestinal disease location. There was no difference in median PCDAI scores between those who had and those who had not oral lesions at follow-up.; OCD resolved in the majority of children treated for intestinal Crohn's disease. The occurrence of mouth lesions during follow-up of children who had oral manifestations at initial diagnosis was not a marker for Crohn's disease activity elsewhere in the intestinal tract.
Item Type:
Article
Language:
en
MeSH:
Adolescent; Crohn Disease; Female; Follow-Up Studies; Humans; Male; Mouth Diseases; Severity of Illness Index; Treatment Outcome; Young Adult
ISSN:
1818-6300

Full metadata record

DC FieldValue Language
dc.contributor.authorHussey, Sen
dc.contributor.authorFleming, Pen
dc.contributor.authorRowland, Men
dc.contributor.authorHarty, Sen
dc.contributor.authorChan, Len
dc.contributor.authorBroderick, Aen
dc.contributor.authorDrumm, Ben
dc.contributor.authorBourke, Ben
dc.date.accessioned2011-08-10T08:42:33Z-
dc.date.available2011-08-10T08:42:33Z-
dc.date.issued2011-06-
dc.identifier.citationDisease outcome for children who present with oral manifestations of Crohn's disease. 2011, 12 (3):167-9 Eur Arch Paediatr Denten
dc.identifier.issn1818-6300-
dc.identifier.pmid21640063-
dc.identifier.urihttp://hdl.handle.net/10147/139289-
dc.description.abstractTo describe the outcome for children with oral Crohn's disease (OCD) at diagnosis, and to determine if there was a difference in the Paediatric Crohn's Disease Activity Index (PCDAI) scores between those with and those without oral lesions at follow-up.-
dc.description.abstractThirty-one patients with OCD who had enrolled in two previous studies were invited to participate. Clinical and laboratory data were collected to calculate the PCDAI. Details of the management of Crohn's disease were also recorded.-
dc.description.abstractTwenty-four of 31 patients participated (77%), of whom 17 were boys (M:F = 2.4:1). Mean age at follow-up was 15.7 years (SD 1.98, range 11.9-19.7 years). Mean duration of follow-up was 55 months (SD 22, range 20-97 months). Oral manifestations were present at follow-up in 7 (29%) of 24 patients. There were no differences between patients with and without OCD at follow-up with regard to medical treatments received or intestinal disease location. There was no difference in median PCDAI scores between those who had and those who had not oral lesions at follow-up.-
dc.description.abstractOCD resolved in the majority of children treated for intestinal Crohn's disease. The occurrence of mouth lesions during follow-up of children who had oral manifestations at initial diagnosis was not a marker for Crohn's disease activity elsewhere in the intestinal tract.-
dc.language.isoenen
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/21640063en
dc.subject.meshAdolescent-
dc.subject.meshCrohn Disease-
dc.subject.meshFemale-
dc.subject.meshFollow-Up Studies-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMouth Diseases-
dc.subject.meshSeverity of Illness Index-
dc.subject.meshTreatment Outcome-
dc.subject.meshYoung Adult-
dc.titleDisease outcome for children who present with oral manifestations of Crohn's disease.en
dc.typeArticleen
dc.contributor.departmentDublin Dental University Hospital, Trinity College Dublin, Dublin 2, Ireland.en
dc.identifier.journalEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistryen
dc.description.provinceLeinster-

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