Use of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction.

Hdl Handle:
http://hdl.handle.net/10147/136381
Title:
Use of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction.
Authors:
O'Connell, K; Boo, T W; Keady, D; Niriain, U; O'Donovan, D; Commane, M; Faherty, C; Cormican, M
Affiliation:
Department of Clinical Microbiology, University College Hospital, Galway, Ireland. karinaoconnell@gmail.com
Citation:
Use of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction. 2011, 77 (4):338-42 J. Hosp. Infect.
Journal:
The Journal of hospital infection
Issue Date:
Apr-2011
URI:
http://hdl.handle.net/10147/136381
DOI:
10.1016/j.jhin.2010.12.012
PubMed ID:
21330007
Additional Links:
http://www.ncbi.nlm.nih.gov/pubmed/21330007
Abstract:
Respiratory syncytial virus (RSV) is a potentially life-threatening infection in premature infants. We report an outbreak involving four infants in the neonatal intensive care unit (NICU) of our hospital that occurred in February 2010. RSV A infection was confirmed by real-time polymerase chain reaction. Palivizumab was administered to all infants in the NICU. There were no additional symptomatic cases and repeat RSV surveillance confirmed that there was no further cross-transmission within the unit. The outbreak highlighted the infection control challenge of very high bed occupancy in the unit and the usefulness of molecular methods in facilitating detection and management.
Item Type:
Article
Language:
en
MeSH:
Antibodies, Monoclonal; Antiviral Agents; Cross Infection; DNA, Viral; Disease Outbreaks; Female; Genotype; Humans; Infant; Infant, Newborn; Infection Control; Intensive Care, Neonatal; Polymerase Chain Reaction; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human
ISSN:
1532-2939

Full metadata record

DC FieldValue Language
dc.contributor.authorO'Connell, Ken
dc.contributor.authorBoo, T Wen
dc.contributor.authorKeady, Den
dc.contributor.authorNiriain, Uen
dc.contributor.authorO'Donovan, Den
dc.contributor.authorCommane, Men
dc.contributor.authorFaherty, Cen
dc.contributor.authorCormican, Men
dc.date.accessioned2011-07-20T11:14:56Z-
dc.date.available2011-07-20T11:14:56Z-
dc.date.issued2011-04-
dc.identifier.citationUse of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction. 2011, 77 (4):338-42 J. Hosp. Infect.en
dc.identifier.issn1532-2939-
dc.identifier.pmid21330007-
dc.identifier.doi10.1016/j.jhin.2010.12.012-
dc.identifier.urihttp://hdl.handle.net/10147/136381-
dc.description.abstractRespiratory syncytial virus (RSV) is a potentially life-threatening infection in premature infants. We report an outbreak involving four infants in the neonatal intensive care unit (NICU) of our hospital that occurred in February 2010. RSV A infection was confirmed by real-time polymerase chain reaction. Palivizumab was administered to all infants in the NICU. There were no additional symptomatic cases and repeat RSV surveillance confirmed that there was no further cross-transmission within the unit. The outbreak highlighted the infection control challenge of very high bed occupancy in the unit and the usefulness of molecular methods in facilitating detection and management.-
dc.language.isoenen
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/21330007en
dc.subject.meshAntibodies, Monoclonal-
dc.subject.meshAntiviral Agents-
dc.subject.meshCross Infection-
dc.subject.meshDNA, Viral-
dc.subject.meshDisease Outbreaks-
dc.subject.meshFemale-
dc.subject.meshGenotype-
dc.subject.meshHumans-
dc.subject.meshInfant-
dc.subject.meshInfant, Newborn-
dc.subject.meshInfection Control-
dc.subject.meshIntensive Care, Neonatal-
dc.subject.meshPolymerase Chain Reaction-
dc.subject.meshRespiratory Syncytial Virus Infections-
dc.subject.meshRespiratory Syncytial Virus, Human-
dc.titleUse of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction.en
dc.typeArticleen
dc.contributor.departmentDepartment of Clinical Microbiology, University College Hospital, Galway, Ireland. karinaoconnell@gmail.comen
dc.identifier.journalThe Journal of hospital infectionen
dc.description.provinceConnacht-

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