Pulmonary artery leiomyosarcoma: an unusual cause of shortness of breath.

Hdl Handle:
http://hdl.handle.net/10147/135575
Title:
Pulmonary artery leiomyosarcoma: an unusual cause of shortness of breath.
Authors:
Flaherty, G; McCarthy, P; Mortimer, G
Affiliation:
Department of Medicine, University Hospital, Galway and National University of Ireland, Galway, Ireland. gerard.flaherty@nuigalway.ie
Citation:
Pulmonary artery leiomyosarcoma: an unusual cause of shortness of breath. 2011, 180 (1):275-8 Ir J Med Sci
Journal:
Irish journal of medical science
Issue Date:
Mar-2011
URI:
http://hdl.handle.net/10147/135575
DOI:
10.1007/s11845-009-0451-0
PubMed ID:
19921308
Additional Links:
http://www.ncbi.nlm.nih.gov/pubmed/19921308
Abstract:
Primary leiomyosarcomas of the pulmonary artery are very rare tumours with 30 cases reported in the English literature. Herein, we report the first case with evidence of a renal metastasis.; The tumour was discovered at autopsy in a 61-year-old woman who had presented with shortness of breath and chest pain. It was located in the pulmonary trunk with extension into the adjacent pericardial cavity. Separate nodules were found in the pulmonary valve, the left pulmonary artery and the left kidney.; On microscopic examination, the tumour was composed of spindle cells with cigar-shaped nuclei immunoreactive for vimentin, desmin, CD68 and α-smooth muscle actin.; Primary pulmonary artery leiomyosarcoma is easily confused clinically with pulmonary thromboembolism and most cases are diagnosed post mortem. Most tumours arise in the pulmonary trunk and metastases are only rarely described. The management of patients with this rare tumour depends on early surgical resection and the prognosis is unfavourable.
Item Type:
Article
Language:
en
MeSH:
Bromhexine; Dyspnea; Female; Humans; Immunohistochemistry; Kidney Neoplasms; Leiomyosarcoma; Middle Aged; Pulmonary Artery; Vascular Neoplasms
ISSN:
1863-4362

Full metadata record

DC FieldValue Language
dc.contributor.authorFlaherty, Gen
dc.contributor.authorMcCarthy, Pen
dc.contributor.authorMortimer, Gen
dc.date.accessioned2011-07-07T14:54:02Z-
dc.date.available2011-07-07T14:54:02Z-
dc.date.issued2011-03-
dc.identifier.citationPulmonary artery leiomyosarcoma: an unusual cause of shortness of breath. 2011, 180 (1):275-8 Ir J Med Scien
dc.identifier.issn1863-4362-
dc.identifier.pmid19921308-
dc.identifier.doi10.1007/s11845-009-0451-0-
dc.identifier.urihttp://hdl.handle.net/10147/135575-
dc.description.abstractPrimary leiomyosarcomas of the pulmonary artery are very rare tumours with 30 cases reported in the English literature. Herein, we report the first case with evidence of a renal metastasis.-
dc.description.abstractThe tumour was discovered at autopsy in a 61-year-old woman who had presented with shortness of breath and chest pain. It was located in the pulmonary trunk with extension into the adjacent pericardial cavity. Separate nodules were found in the pulmonary valve, the left pulmonary artery and the left kidney.-
dc.description.abstractOn microscopic examination, the tumour was composed of spindle cells with cigar-shaped nuclei immunoreactive for vimentin, desmin, CD68 and α-smooth muscle actin.-
dc.description.abstractPrimary pulmonary artery leiomyosarcoma is easily confused clinically with pulmonary thromboembolism and most cases are diagnosed post mortem. Most tumours arise in the pulmonary trunk and metastases are only rarely described. The management of patients with this rare tumour depends on early surgical resection and the prognosis is unfavourable.-
dc.language.isoenen
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/19921308en
dc.subject.meshBromhexine-
dc.subject.meshDyspnea-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshImmunohistochemistry-
dc.subject.meshKidney Neoplasms-
dc.subject.meshLeiomyosarcoma-
dc.subject.meshMiddle Aged-
dc.subject.meshPulmonary Artery-
dc.subject.meshVascular Neoplasms-
dc.titlePulmonary artery leiomyosarcoma: an unusual cause of shortness of breath.en
dc.typeArticleen
dc.contributor.departmentDepartment of Medicine, University Hospital, Galway and National University of Ireland, Galway, Ireland. gerard.flaherty@nuigalway.ieen
dc.identifier.journalIrish journal of medical scienceen
dc.description.provinceConnacht-

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