Proximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literature

Hdl Handle:
http://hdl.handle.net/10147/134174
Title:
Proximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literature
Authors:
Thabit, Hood; Barry, Maurice; Sreenan, Seamus; Smith, Diarmuid
Citation:
Journal of Medical Case Reports. 2011 May 13;5(1):178
Issue Date:
13-May-2011
URI:
http://hdl.handle.net/10147/134174
Abstract:
Abstract Introduction Severe proximal myopathy can occasionally be the first presenting complaint of patients with osteomalacia. This may lead to investigations and misdiagnosis of a neuromuscular disease, rather than a metabolic bone disease. Case presentations We present here two cases of severe proximal myopathy in patients who were both of South Asian origin and lacto-vegetarians: a 31-year-old Indian man and a 34-year-old Indian woman. In both cases, their clinical symptoms fully resolved following vitamin D and calcium replacement therapy. These patients were at risk of osteomalacia due to their dietary intake and ethnicity. The role of dietary intake and sunlight exposure in the development of osteomalacia in certain ethnic groups living in Western Europe is reviewed here. Conclusion These two cases emphasize the importance of recognizing osteomalacia in at-risk individuals, as the condition is reversible and easily treated with vitamin D and calcium supplementation. It may also help avoid prolonged and unnecessary investigations of these patients.
Item Type:
Journal Article

Full metadata record

DC FieldValue Language
dc.contributor.authorThabit, Hood-
dc.contributor.authorBarry, Maurice-
dc.contributor.authorSreenan, Seamus-
dc.contributor.authorSmith, Diarmuid-
dc.date.accessioned2011-06-22T11:22:32Z-
dc.date.available2011-06-22T11:22:32Z-
dc.date.issued2011-05-13-
dc.identifierhttp://dx.doi.org/10.1186/1752-1947-5-178-
dc.identifier.citationJournal of Medical Case Reports. 2011 May 13;5(1):178-
dc.identifier.urihttp://hdl.handle.net/10147/134174-
dc.description.abstractAbstract Introduction Severe proximal myopathy can occasionally be the first presenting complaint of patients with osteomalacia. This may lead to investigations and misdiagnosis of a neuromuscular disease, rather than a metabolic bone disease. Case presentations We present here two cases of severe proximal myopathy in patients who were both of South Asian origin and lacto-vegetarians: a 31-year-old Indian man and a 34-year-old Indian woman. In both cases, their clinical symptoms fully resolved following vitamin D and calcium replacement therapy. These patients were at risk of osteomalacia due to their dietary intake and ethnicity. The role of dietary intake and sunlight exposure in the development of osteomalacia in certain ethnic groups living in Western Europe is reviewed here. Conclusion These two cases emphasize the importance of recognizing osteomalacia in at-risk individuals, as the condition is reversible and easily treated with vitamin D and calcium supplementation. It may also help avoid prolonged and unnecessary investigations of these patients.-
dc.titleProximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literature-
dc.typeJournal Article-
dc.language.rfc3066en-
dc.rights.holderThabit et al.; licensee BioMed Central Ltd.-
dc.description.statusPeer Reviewed-
dc.date.updated2011-06-13T16:05:47Z-
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