The role of topical antibiotics used as prophylaxis in surgical site infection prevention.

Hdl Handle:
http://hdl.handle.net/10147/132324
Title:
The role of topical antibiotics used as prophylaxis in surgical site infection prevention.
Authors:
McHugh, S M; Collins, C J; Corrigan, M A; Hill, A D K; Humphreys, H
Affiliation:
Department of Surgery, Royal College of Surgeons in Ireland, and Beaumont Hospital, Dublin, Ireland. seamusmchugh@rcsi.ie
Citation:
The role of topical antibiotics used as prophylaxis in surgical site infection prevention. 2011, 66 (4):693-701 J. Antimicrob. Chemother.
Journal:
The Journal of antimicrobial chemotherapy
Issue Date:
Apr-2011
URI:
http://hdl.handle.net/10147/132324
DOI:
10.1093/jac/dkr009
PubMed ID:
21393223
Additional Links:
http://www.ncbi.nlm.nih.gov/pubmed/21393223
Abstract:
Compared with systemic antibiotic therapy, the topical or local delivery of an antibiotic has many potential advantages. However, local antibiotics at the surgical site have received very limited approval in any of the surgical prophylaxis consensus guidelines that we are aware of. A review of the literature was carried out through searches of peer-reviewed publications in PubMed in the English language over a 30 year period between January 1980 and May 2010. Both retrospective and prospective studies were included, as well as meta-analyses. With regard to defining 'topical' or 'local' antibiotic application, the application of an antibiotic solution to the surgical site intraoperatively or immediately post-operatively was included. A number of surgical procedures have been shown to significantly benefit from perioperative topical prophylaxis, e.g. joint arthroplasty, cataract surgery and, possibly, breast augmentation. In obese patients undergoing abdominal surgery, topical surgical prophylaxis is also proven to be beneficial. The selective use of topical antibiotics as surgical prophylaxis is justified for specific procedures, such as joint arthroplasty, cataract surgery and, possibly, breast augmentation. In selective cases, such as obese patients undergoing abdominal surgery, topical surgical prophylaxis is also proven to be beneficial. Apart from these specific indications, the evidence for use of topical antibiotics in surgery is lacking in conclusive randomized controlled trials.
Item Type:
Article
Language:
en
ISSN:
1460-2091

Full metadata record

DC FieldValue Language
dc.contributor.authorMcHugh, S Men
dc.contributor.authorCollins, C Jen
dc.contributor.authorCorrigan, M Aen
dc.contributor.authorHill, A D Ken
dc.contributor.authorHumphreys, Hen
dc.date.accessioned2011-05-30T15:25:13Z-
dc.date.available2011-05-30T15:25:13Z-
dc.date.issued2011-04-
dc.identifier.citationThe role of topical antibiotics used as prophylaxis in surgical site infection prevention. 2011, 66 (4):693-701 J. Antimicrob. Chemother.en
dc.identifier.issn1460-2091-
dc.identifier.pmid21393223-
dc.identifier.doi10.1093/jac/dkr009-
dc.identifier.urihttp://hdl.handle.net/10147/132324-
dc.description.abstractCompared with systemic antibiotic therapy, the topical or local delivery of an antibiotic has many potential advantages. However, local antibiotics at the surgical site have received very limited approval in any of the surgical prophylaxis consensus guidelines that we are aware of. A review of the literature was carried out through searches of peer-reviewed publications in PubMed in the English language over a 30 year period between January 1980 and May 2010. Both retrospective and prospective studies were included, as well as meta-analyses. With regard to defining 'topical' or 'local' antibiotic application, the application of an antibiotic solution to the surgical site intraoperatively or immediately post-operatively was included. A number of surgical procedures have been shown to significantly benefit from perioperative topical prophylaxis, e.g. joint arthroplasty, cataract surgery and, possibly, breast augmentation. In obese patients undergoing abdominal surgery, topical surgical prophylaxis is also proven to be beneficial. The selective use of topical antibiotics as surgical prophylaxis is justified for specific procedures, such as joint arthroplasty, cataract surgery and, possibly, breast augmentation. In selective cases, such as obese patients undergoing abdominal surgery, topical surgical prophylaxis is also proven to be beneficial. Apart from these specific indications, the evidence for use of topical antibiotics in surgery is lacking in conclusive randomized controlled trials.-
dc.language.isoenen
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/21393223en
dc.titleThe role of topical antibiotics used as prophylaxis in surgical site infection prevention.en
dc.typeArticleen
dc.contributor.departmentDepartment of Surgery, Royal College of Surgeons in Ireland, and Beaumont Hospital, Dublin, Ireland. seamusmchugh@rcsi.ieen
dc.identifier.journalThe Journal of antimicrobial chemotherapyen
dc.description.provinceLeinster-

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.