Prevalence of left-sided melanomas in an Irish population.

Hdl Handle:
http://hdl.handle.net/10147/132312
Title:
Prevalence of left-sided melanomas in an Irish population.
Authors:
de Blacam, C; Ho, W L; Acton, C; Murphy, G; Kneafsey, B; Hill, A D K
Affiliation:
Department of Surgery, Beaumont Hospital, Royal College of Surgeons in Ireland, Dublin, Ireland, catherinedeblacam@rcsi.ie.
Citation:
Prevalence of left-sided melanomas in an Irish population. 2011:notIr J Med Sci
Journal:
Irish journal of medical science
Issue Date:
17-Apr-2011
URI:
http://hdl.handle.net/10147/132312
DOI:
10.1007/s11845-011-0713-5
PubMed ID:
21499924
Additional Links:
http://www.ncbi.nlm.nih.gov/pubmed/21499924
Abstract:
BACKGROUND: A predominance of melanomas on the left side of the body has recently been described. No associations between tumour laterality and gender, age or anatomical site have been identified. AIM: The aim of this study was to investigate the prevalence of left-sided melanomas in an Irish population and to examine potential associations with various patient and tumour characteristics. METHODS: A retrospective chart review of patients with cutaneous melanoma who were treated over a 10-year period was carried out. Lateral distribution of melanoma on either side of the body was compared using χ(2) analysis and evaluated by gender, age group, anatomic location, histologic subtype and Breslow depth. RESULTS: More melanomas occurred on the left side (57%, P = 0.015), and this finding was particularly significant in females. For both genders combined, there were no statistically significant differences in laterality by age group, anatomic location, type of melanoma and Breslow depth. There were significantly more superficial spreading melanomas on the left side in both men and women. CONCLUSIONS: This study demonstrates a predominance of left-sided melanomas in Irish patients. While a number of demographic and molecular associations have been proposed, further research is required to fully explain this phenomenon.
Item Type:
Article
Language:
en
ISSN:
1863-4362

Full metadata record

DC FieldValue Language
dc.contributor.authorde Blacam, Cen
dc.contributor.authorHo, W Len
dc.contributor.authorActon, Cen
dc.contributor.authorMurphy, Gen
dc.contributor.authorKneafsey, Ben
dc.contributor.authorHill, A D Ken
dc.date.accessioned2011-05-30T07:56:35Z-
dc.date.available2011-05-30T07:56:35Z-
dc.date.issued2011-04-17-
dc.identifier.citationPrevalence of left-sided melanomas in an Irish population. 2011:notIr J Med Scien
dc.identifier.issn1863-4362-
dc.identifier.pmid21499924-
dc.identifier.doi10.1007/s11845-011-0713-5-
dc.identifier.urihttp://hdl.handle.net/10147/132312-
dc.description.abstractBACKGROUND: A predominance of melanomas on the left side of the body has recently been described. No associations between tumour laterality and gender, age or anatomical site have been identified. AIM: The aim of this study was to investigate the prevalence of left-sided melanomas in an Irish population and to examine potential associations with various patient and tumour characteristics. METHODS: A retrospective chart review of patients with cutaneous melanoma who were treated over a 10-year period was carried out. Lateral distribution of melanoma on either side of the body was compared using χ(2) analysis and evaluated by gender, age group, anatomic location, histologic subtype and Breslow depth. RESULTS: More melanomas occurred on the left side (57%, P = 0.015), and this finding was particularly significant in females. For both genders combined, there were no statistically significant differences in laterality by age group, anatomic location, type of melanoma and Breslow depth. There were significantly more superficial spreading melanomas on the left side in both men and women. CONCLUSIONS: This study demonstrates a predominance of left-sided melanomas in Irish patients. While a number of demographic and molecular associations have been proposed, further research is required to fully explain this phenomenon.-
dc.languageENG-
dc.language.isoenen
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/21499924en
dc.titlePrevalence of left-sided melanomas in an Irish population.en
dc.typeArticleen
dc.contributor.departmentDepartment of Surgery, Beaumont Hospital, Royal College of Surgeons in Ireland, Dublin, Ireland, catherinedeblacam@rcsi.ie.en
dc.identifier.journalIrish journal of medical scienceen
dc.description.provinceLeinster-

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