Affiliation
Department of Respiratory Medicine, Naas General Hospital, Trinity College Dublin, Kildare, Ireland. sb72pk@yahoo.comIssue Date
2010-11MeSH
AdultAntitubercular Agents
Drug Resistance, Bacterial
Female
Humans
Isoniazid
Male
Microbial Sensitivity Tests
Middle Aged
Mycobacterium bovis
Pyrazinamide
Radiography, Thoracic
Tomography, X-Ray Computed
Treatment Outcome
Tuberculosis
Metadata
Show full item recordCitation
Human bovine tuberculosis - remains in the differential. 2010, 59 (Pt 11):1379-82 J. Med. Microbiol.Journal
Journal of medical microbiologyDOI
10.1099/jmm.0.020511-0PubMed ID
20688950Additional Links
http://jmm.sgmjournals.org/cgi/content/full/59/11/1379Abstract
Mycobacterium bovis is a pathogen of cattle. The unpasteurized milk of affected cattle is a source of infection in humans. Despite the screening of cattle and the pasteurization of milk, M bovis has not been eradicated. A high index of clinical suspicion is needed in symptomatic patients with a history of possible exposure. At risk groups include animal workers, farmers, meat packers, vets and zoo keepers. Humans are usually infected by the aerosol route. We present two cases of human bovine tuberculosis. One was a presumptive case and the second was a confirmed case. Both responded well to antituberculous therapy. In the confirmed case, there was evidence of transmission to the partner living in the same house. Rifampicin prophylaxis was given to the exposed case. The M. bovis from the confirmed case was isoniazid resistant, in addition to having the well known resistance to pyrazinamide. Isoniazid resistance has been described before in those who are immunocompromised. We describe it in an immunocompetent patient.Item Type
ArticleLanguage
enISSN
1473-5644ae974a485f413a2113503eed53cd6c53
10.1099/jmm.0.020511-0
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