Human bovine tuberculosis - remains in the differential.

2.50
Hdl Handle:
http://hdl.handle.net/10147/132284
Title:
Human bovine tuberculosis - remains in the differential.
Authors:
Bilal, Shaukat; Iqbal, Mudassir; Murphy, Philip; Power, Joan
Affiliation:
Department of Respiratory Medicine, Naas General Hospital, Trinity College Dublin, Kildare, Ireland. sb72pk@yahoo.com
Citation:
Human bovine tuberculosis - remains in the differential. 2010, 59 (Pt 11):1379-82 J. Med. Microbiol.
Journal:
Journal of medical microbiology
Issue Date:
Nov-2010
URI:
http://hdl.handle.net/10147/132284
DOI:
10.1099/jmm.0.020511-0
PubMed ID:
20688950
Additional Links:
http://jmm.sgmjournals.org/cgi/content/full/59/11/1379
Abstract:
Mycobacterium bovis is a pathogen of cattle. The unpasteurized milk of affected cattle is a source of infection in humans. Despite the screening of cattle and the pasteurization of milk, M bovis has not been eradicated. A high index of clinical suspicion is needed in symptomatic patients with a history of possible exposure. At risk groups include animal workers, farmers, meat packers, vets and zoo keepers. Humans are usually infected by the aerosol route. We present two cases of human bovine tuberculosis. One was a presumptive case and the second was a confirmed case. Both responded well to antituberculous therapy. In the confirmed case, there was evidence of transmission to the partner living in the same house. Rifampicin prophylaxis was given to the exposed case. The M. bovis from the confirmed case was isoniazid resistant, in addition to having the well known resistance to pyrazinamide. Isoniazid resistance has been described before in those who are immunocompromised. We describe it in an immunocompetent patient.
Item Type:
Article
Language:
en
MeSH:
Adult; Antitubercular Agents; Drug Resistance, Bacterial; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium bovis; Pyrazinamide; Radiography, Thoracic; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis
ISSN:
1473-5644

Full metadata record

DC FieldValue Language
dc.contributor.authorBilal, Shaukaten
dc.contributor.authorIqbal, Mudassiren
dc.contributor.authorMurphy, Philipen
dc.contributor.authorPower, Joanen
dc.date.accessioned2011-05-27T15:39:41Z-
dc.date.available2011-05-27T15:39:41Z-
dc.date.issued2010-11-
dc.identifier.citationHuman bovine tuberculosis - remains in the differential. 2010, 59 (Pt 11):1379-82 J. Med. Microbiol.en
dc.identifier.issn1473-5644-
dc.identifier.pmid20688950-
dc.identifier.doi10.1099/jmm.0.020511-0-
dc.identifier.urihttp://hdl.handle.net/10147/132284-
dc.description.abstractMycobacterium bovis is a pathogen of cattle. The unpasteurized milk of affected cattle is a source of infection in humans. Despite the screening of cattle and the pasteurization of milk, M bovis has not been eradicated. A high index of clinical suspicion is needed in symptomatic patients with a history of possible exposure. At risk groups include animal workers, farmers, meat packers, vets and zoo keepers. Humans are usually infected by the aerosol route. We present two cases of human bovine tuberculosis. One was a presumptive case and the second was a confirmed case. Both responded well to antituberculous therapy. In the confirmed case, there was evidence of transmission to the partner living in the same house. Rifampicin prophylaxis was given to the exposed case. The M. bovis from the confirmed case was isoniazid resistant, in addition to having the well known resistance to pyrazinamide. Isoniazid resistance has been described before in those who are immunocompromised. We describe it in an immunocompetent patient.-
dc.language.isoenen
dc.relation.urlhttp://jmm.sgmjournals.org/cgi/content/full/59/11/1379en
dc.subject.meshAdult-
dc.subject.meshAntitubercular Agents-
dc.subject.meshDrug Resistance, Bacterial-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshIsoniazid-
dc.subject.meshMale-
dc.subject.meshMicrobial Sensitivity Tests-
dc.subject.meshMiddle Aged-
dc.subject.meshMycobacterium bovis-
dc.subject.meshPyrazinamide-
dc.subject.meshRadiography, Thoracic-
dc.subject.meshTomography, X-Ray Computed-
dc.subject.meshTreatment Outcome-
dc.subject.meshTuberculosis-
dc.titleHuman bovine tuberculosis - remains in the differential.en
dc.typeArticleen
dc.contributor.departmentDepartment of Respiratory Medicine, Naas General Hospital, Trinity College Dublin, Kildare, Ireland. sb72pk@yahoo.comen
dc.identifier.journalJournal of medical microbiologyen
dc.description.provinceLeinster-

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