Irish Health Repository >
Hospital Research >
St. Vincent's Hospital Fairview >
Acoustic and temporal analysis of speech: A potential biomarker for schizophrenia.
|Files in This Item:|
There are no files associated with this item.
|Title: ||Acoustic and temporal analysis of speech: A potential biomarker for schizophrenia.|
|Affiliation: ||Trinity Centre for Bioengineering, Trinity College Dublin, Dublin 2, Ireland. firstname.lastname@example.org|
|Citation: ||Acoustic and temporal analysis of speech: A potential biomarker for schizophrenia. 2010, 32 (9):1074-9 Med Eng Phys|
|Journal: ||Medical engineering & physics|
|Issue Date: ||Nov-2010 |
|PubMed ID: ||20692864|
|Abstract: ||Currently, there are no established objective biomarkers for the diagnosis or monitoring of schizophrenia. It has been previously reported that there are notable qualitative differences in the speech of schizophrenics. The objective of this study was to determine whether a quantitative acoustic and temporal analysis of speech may be a potential biomarker for schizophrenia. In this study, 39 schizophrenic patients and 18 controls were digitally recorded reading aloud an emotionally neutral text passage from a children's story. Temporal, energy and vocal pitch features were automatically extracted from the recordings. A classifier based on linear discriminant analysis was employed to differentiate between controls and schizophrenic subjects. Processing the recordings with the algorithm developed demonstrated that it is possible to differentiate schizophrenic patients and controls with a classification accuracy of 79.4% (specificity=83.6%, sensitivity=75.2%) based on speech pause related parameters extracted from recordings carried out in standard office (non-studio) environments. Acoustic and temporal analysis of speech may represent a potential tool for the objective analysis in schizophrenia.|
|Type: ||Article In Press|
|Appears in Collections: ||St. Vincent's Hospital Fairview|
this identifier to cite or link
to this item:
|Related articles on PubMed|
Exploratory eye movement dysfunction as a discriminator for schizophrenia : a large sample study using a newly developed digital computerized system.
Suzuki M, Takahashi S, Matsushima E, Tsunoda M, Kurachi M, Okada T, Hayashi T, Ishii Y, Morita K, Maeda H, Katayama S, Kawahara R, Otsuka T, Hirayasu Y, Sekine M, Okubo Y, Motoshita M, Ohta K, Uchiyama M, Kojima T
|See all 97 articles|
All Items in LENUS are protected by copyright, with all rights reserved, unless otherwise indicated.