Illicit substance use and its correlates in first episode psychosis.

Hdl Handle:
http://hdl.handle.net/10147/128743
Title:
Illicit substance use and its correlates in first episode psychosis.
Authors:
Mazzoncini, R; Donoghue, K; Hart, J; Morgan, C; Doody, G A; Dazzan, P; Jones, P B; Morgan, K; Murray, R M; Fearon, P
Affiliation:
Department of Medicine and Public Health, University of Verona, Italy. rodolfo.mazzoncini@univr.it <rodolfo.mazzoncini@univr.it>
Citation:
Illicit substance use and its correlates in first episode psychosis. 2010, 121 (5):351-8 Acta Psychiatr Scand
Journal:
Acta psychiatrica Scandinavica
Issue Date:
May-2010
URI:
http://hdl.handle.net/10147/128743
DOI:
10.1111/j.1600-0447.2009.01483.x
PubMed ID:
19824986
Additional Links:
DOI: 10.1111/j.1600-0447.2009.01483.x
Abstract:
To determine if substance use (particularly cannabis) is more frequent among first episode psychosis patients and associated with a more problematic clinical presentation.; All first episode psychosis (FEP) patients presenting to secondary services were recruited from London and Nottingham, over 2 years, in the Aetiology and Ethnicity of Schizophrenia and Other Psychoses study broad framework. Clinical and sociodemographic variables were assessed using a set of standardized instruments. A schedule was created to retrospectively collate substance use data from patients, relatives and clinicians.; Five hundred and eleven FEP were identified. They used three to five times more substances than general population. Substance use was associated with poorer social adjustment and a more acute mode of onset. Cannabis use did not affect social adjustment, but was associated with a more acute mode of onset.; Cannabis has a different impact on FEP than other substances. Large epidemiological studies are needed to disentangle cannabis effect.
Language:
en
MeSH:
Acute Disease; Adolescent; Adult; Age of Onset; Comorbidity; Cross-Cultural Comparison; Cross-Sectional Studies; England; Female; Humans; Male; Marijuana Abuse; Middle Aged; Psychoses, Substance-Induced; Psychotic Disorders; Retrospective Studies; Social Adjustment; Street Drugs; Substance-Related Disorders; Young Adult
ISSN:
1600-0447

Full metadata record

DC FieldValue Language
dc.contributor.authorMazzoncini, Ren
dc.contributor.authorDonoghue, Ken
dc.contributor.authorHart, Jen
dc.contributor.authorMorgan, Cen
dc.contributor.authorDoody, G Aen
dc.contributor.authorDazzan, Pen
dc.contributor.authorJones, P Ben
dc.contributor.authorMorgan, Ken
dc.contributor.authorMurray, R Men
dc.contributor.authorFearon, Pen
dc.date.accessioned2011-04-27T11:00:32Z-
dc.date.available2011-04-27T11:00:32Z-
dc.date.issued2010-05-
dc.identifier.citationIllicit substance use and its correlates in first episode psychosis. 2010, 121 (5):351-8 Acta Psychiatr Scanden
dc.identifier.issn1600-0447-
dc.identifier.pmid19824986-
dc.identifier.doi10.1111/j.1600-0447.2009.01483.x-
dc.identifier.urihttp://hdl.handle.net/10147/128743-
dc.description.abstractTo determine if substance use (particularly cannabis) is more frequent among first episode psychosis patients and associated with a more problematic clinical presentation.-
dc.description.abstractAll first episode psychosis (FEP) patients presenting to secondary services were recruited from London and Nottingham, over 2 years, in the Aetiology and Ethnicity of Schizophrenia and Other Psychoses study broad framework. Clinical and sociodemographic variables were assessed using a set of standardized instruments. A schedule was created to retrospectively collate substance use data from patients, relatives and clinicians.-
dc.description.abstractFive hundred and eleven FEP were identified. They used three to five times more substances than general population. Substance use was associated with poorer social adjustment and a more acute mode of onset. Cannabis use did not affect social adjustment, but was associated with a more acute mode of onset.-
dc.description.abstractCannabis has a different impact on FEP than other substances. Large epidemiological studies are needed to disentangle cannabis effect.-
dc.language.isoenen
dc.relation.urlDOI: 10.1111/j.1600-0447.2009.01483.xen
dc.subject.meshAcute Disease-
dc.subject.meshAdolescent-
dc.subject.meshAdult-
dc.subject.meshAge of Onset-
dc.subject.meshComorbidity-
dc.subject.meshCross-Cultural Comparison-
dc.subject.meshCross-Sectional Studies-
dc.subject.meshEngland-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMarijuana Abuse-
dc.subject.meshMiddle Aged-
dc.subject.meshPsychoses, Substance-Induced-
dc.subject.meshPsychotic Disorders-
dc.subject.meshRetrospective Studies-
dc.subject.meshSocial Adjustment-
dc.subject.meshStreet Drugs-
dc.subject.meshSubstance-Related Disorders-
dc.subject.meshYoung Adult-
dc.titleIllicit substance use and its correlates in first episode psychosis.en
dc.contributor.departmentDepartment of Medicine and Public Health, University of Verona, Italy. rodolfo.mazzoncini@univr.it <rodolfo.mazzoncini@univr.it>en
dc.identifier.journalActa psychiatrica Scandinavicaen
dc.description.provinceLeinster-

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