Inflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link.

Hdl Handle:
http://hdl.handle.net/10147/128251
Title:
Inflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link.
Authors:
Conroy, H; Mawhinney, L; Donnelly, S C
Affiliation:
Conway Institute for Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland.
Citation:
Inflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link. 2010, 103 (11):831-6 QJM
Journal:
QJM : monthly journal of the Association of Physicians
Issue Date:
Nov-2010
URI:
http://hdl.handle.net/10147/128251
DOI:
10.1093/qjmed/hcq148
PubMed ID:
20805118
Abstract:
Macrophage migration inhibitory factor (MIF) was the original cytokine, described almost 50 years ago and has since been revealed to be an important player in pro-inflammatory diseases. Recent work using MIF mouse models has revealed new roles for MIF. In this review, we present an increasing body of evidence implicating the key pro-inflammatory cytokine MIF in specific biological activities related directly to cancer growth or contributing towards a microenvironment favouring cancer progression.
Item Type:
Article
Language:
en
MeSH:
Animals; Biological Markers; Cell Hypoxia; Disease Progression; Humans; Inflammation; Macrophage Migration-Inhibitory Factors; Mice; Neoplasms; Neovascularization, Pathologic
ISSN:
1460-2393

Full metadata record

DC FieldValue Language
dc.contributor.authorConroy, Hen
dc.contributor.authorMawhinney, Len
dc.contributor.authorDonnelly, S Cen
dc.date.accessioned2011-04-18T09:05:53Z-
dc.date.available2011-04-18T09:05:53Z-
dc.date.issued2010-11-
dc.identifier.citationInflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link. 2010, 103 (11):831-6 QJMen
dc.identifier.issn1460-2393-
dc.identifier.pmid20805118-
dc.identifier.doi10.1093/qjmed/hcq148-
dc.identifier.urihttp://hdl.handle.net/10147/128251-
dc.description.abstractMacrophage migration inhibitory factor (MIF) was the original cytokine, described almost 50 years ago and has since been revealed to be an important player in pro-inflammatory diseases. Recent work using MIF mouse models has revealed new roles for MIF. In this review, we present an increasing body of evidence implicating the key pro-inflammatory cytokine MIF in specific biological activities related directly to cancer growth or contributing towards a microenvironment favouring cancer progression.-
dc.language.isoenen
dc.subject.meshAnimals-
dc.subject.meshBiological Markers-
dc.subject.meshCell Hypoxia-
dc.subject.meshDisease Progression-
dc.subject.meshHumans-
dc.subject.meshInflammation-
dc.subject.meshMacrophage Migration-Inhibitory Factors-
dc.subject.meshMice-
dc.subject.meshNeoplasms-
dc.subject.meshNeovascularization, Pathologic-
dc.titleInflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link.en
dc.typeArticleen
dc.contributor.departmentConway Institute for Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland.en
dc.identifier.journalQJM : monthly journal of the Association of Physiciansen
All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.