Neonatal respiratory extracorporeal membrane oxygenation (ECMO) referrals

Hdl Handle:
http://hdl.handle.net/10147/128166
Title:
Neonatal respiratory extracorporeal membrane oxygenation (ECMO) referrals
Authors:
EL-Khuffash, A; Kieran, E
Publisher:
Irish Medical Journal
Journal:
Irish Medical Journal
Issue Date:
Mar-2011
URI:
http://hdl.handle.net/10147/128166
Item Type:
Article
Language:
en
Description:
Extracorporeal membrane oxygenation (ECMO) is a complex technique for providing life support in neonatal respiratory failure. The UK Collaborative ECMO trial demonstrated cost-effectiveness and substantial improvements in neurological morbidity and mortality. Currently, infants requiring ECMO in Ireland are referred to one of various centres in the UK and Scandinavia. We aimed to review the number of infants referred from Ireland for respiratory ECMO. All infants with a non-cardiac condition referred from Ireland for ECMO were reviewed for diagnosis and outcomes. Eleven infants required ECMO between June 2006 and January 2009 and were referred to the Scandinavian team for ECMO transport although one infant improved and did not require ECMO following the arrival of the team. Four infants died: one infant died prior to arrival of the ECMO team, 3 infants had fatal diagnoses and one infant with congenital diaphragmatic hernia received pre-op ECMO. The median (inter-quartile range) gestational age was 39.7 (38.3 â 40.7) weeks and birth weight of 3.7 (3.2-4.0) kg. The median age at the decision to transfer for ECMO was 13h (4-123) and the team arrived at 23 h (12-132). All infants had a normal cranial ultrasound and echo prior to ECMO and 2 infants had an abnormal MRI post-ECMO. The time on ECMO was 9 days (3-17) and total length of hospital stay was 32 d (23-36). There were no pre-ECMO clinical or biochemical predictors of mortality but survival was influenced by the underlying diagnosis leading to respiratory failure. Neonatal respiratory ECMO is unavailable in Ireland and recently infants have been transferred on ECMO support by the transport ECMO team from the Karolinska Institute in Sweden. Continuing audit of infants requiring ECMO is essential to ensure optimal outcomes.
Keywords:
NEONATE; RESPIRATORY DISORDER
Local subject classification:
EXTRACORPOREAL MEMBRANE OXYGENATION (ECMO)
Sponsors:
Reproduced with permission from the Irish Medical Journal.

Full metadata record

DC FieldValue Language
dc.contributor.authorEL-Khuffash, Aen
dc.contributor.authorKieran, Een
dc.date.accessioned2011-04-15T13:47:24Z-
dc.date.available2011-04-15T13:47:24Z-
dc.date.issued2011-03-
dc.identifier.urihttp://hdl.handle.net/10147/128166-
dc.descriptionExtracorporeal membrane oxygenation (ECMO) is a complex technique for providing life support in neonatal respiratory failure. The UK Collaborative ECMO trial demonstrated cost-effectiveness and substantial improvements in neurological morbidity and mortality. Currently, infants requiring ECMO in Ireland are referred to one of various centres in the UK and Scandinavia. We aimed to review the number of infants referred from Ireland for respiratory ECMO. All infants with a non-cardiac condition referred from Ireland for ECMO were reviewed for diagnosis and outcomes. Eleven infants required ECMO between June 2006 and January 2009 and were referred to the Scandinavian team for ECMO transport although one infant improved and did not require ECMO following the arrival of the team. Four infants died: one infant died prior to arrival of the ECMO team, 3 infants had fatal diagnoses and one infant with congenital diaphragmatic hernia received pre-op ECMO. The median (inter-quartile range) gestational age was 39.7 (38.3 â 40.7) weeks and birth weight of 3.7 (3.2-4.0) kg. The median age at the decision to transfer for ECMO was 13h (4-123) and the team arrived at 23 h (12-132). All infants had a normal cranial ultrasound and echo prior to ECMO and 2 infants had an abnormal MRI post-ECMO. The time on ECMO was 9 days (3-17) and total length of hospital stay was 32 d (23-36). There were no pre-ECMO clinical or biochemical predictors of mortality but survival was influenced by the underlying diagnosis leading to respiratory failure. Neonatal respiratory ECMO is unavailable in Ireland and recently infants have been transferred on ECMO support by the transport ECMO team from the Karolinska Institute in Sweden. Continuing audit of infants requiring ECMO is essential to ensure optimal outcomes.en
dc.description.sponsorshipReproduced with permission from the Irish Medical Journal.en
dc.language.isoenen
dc.publisherIrish Medical Journalen
dc.subjectNEONATEen
dc.subjectRESPIRATORY DISORDERen
dc.subject.otherEXTRACORPOREAL MEMBRANE OXYGENATION (ECMO)en
dc.titleNeonatal respiratory extracorporeal membrane oxygenation (ECMO) referralsen
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen
dc.description.provinceLeinster-
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