Hypophysitis secondary to ruptured Rathke's cyst mimicking neurosarcoidosis.

Hdl Handle:
http://hdl.handle.net/10147/127636
Title:
Hypophysitis secondary to ruptured Rathke's cyst mimicking neurosarcoidosis.
Authors:
Janeczko, Cassandra; McHugh, John; Rawluk, Daniel; Farrell, Michael; Brennan, Paul; Delanty, Norman
Affiliation:
Department of Neurology, Beaumont Hospital, P.O. Box 1297, Beaumont Road, Dublin 9, Ireland. cejaneczko@hotmail.com
Citation:
Hypophysitis secondary to ruptured Rathke's cyst mimicking neurosarcoidosis. 2009, 16 (4):599-600 J Clin Neurosci
Journal:
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Issue Date:
Apr-2009
URI:
http://hdl.handle.net/10147/127636
DOI:
10.1016/j.jocn.2008.04.031
PubMed ID:
19231195
Abstract:
Hypophysitis secondary to a ruptured Rathke's cyst is rare. We describe a 53-year-old female who presented with headache and subsequently developed aseptic meningitis and panhypopituitarism. MRI findings and concomitant cardiac arrhythmia and peripheral vasculitis led to a provisional diagnosis of neurosarcoidosis. There were no respiratory manifestations of sarcoidosis. Improvement was noted with empirical treatment with steroids. Pituitary biopsy was undertaken to confirm the diagnosis prior to treatment with long-term immunosuppression for putative neurosarcoidosis. The biopsy revealed lymphocytic hypophysitis secondary to a ruptured Rathke's cyst. This report highlights a rare pathology and the importance of a tissue diagnosis before undertaking non-surgical management of a pituitary mass.
Item Type:
Article
Language:
en
MeSH:
Aneurysm, Ruptured; Central Nervous System Cysts; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Pituitary Diseases; Tomography, X-Ray
ISSN:
0967-5868

Full metadata record

DC FieldValue Language
dc.contributor.authorJaneczko, Cassandraen
dc.contributor.authorMcHugh, Johnen
dc.contributor.authorRawluk, Danielen
dc.contributor.authorFarrell, Michaelen
dc.contributor.authorBrennan, Paulen
dc.contributor.authorDelanty, Normanen
dc.date.accessioned2011-04-07T08:54:02Z-
dc.date.available2011-04-07T08:54:02Z-
dc.date.issued2009-04-
dc.identifier.citationHypophysitis secondary to ruptured Rathke's cyst mimicking neurosarcoidosis. 2009, 16 (4):599-600 J Clin Neuroscien
dc.identifier.issn0967-5868-
dc.identifier.pmid19231195-
dc.identifier.doi10.1016/j.jocn.2008.04.031-
dc.identifier.urihttp://hdl.handle.net/10147/127636-
dc.description.abstractHypophysitis secondary to a ruptured Rathke's cyst is rare. We describe a 53-year-old female who presented with headache and subsequently developed aseptic meningitis and panhypopituitarism. MRI findings and concomitant cardiac arrhythmia and peripheral vasculitis led to a provisional diagnosis of neurosarcoidosis. There were no respiratory manifestations of sarcoidosis. Improvement was noted with empirical treatment with steroids. Pituitary biopsy was undertaken to confirm the diagnosis prior to treatment with long-term immunosuppression for putative neurosarcoidosis. The biopsy revealed lymphocytic hypophysitis secondary to a ruptured Rathke's cyst. This report highlights a rare pathology and the importance of a tissue diagnosis before undertaking non-surgical management of a pituitary mass.-
dc.language.isoenen
dc.subject.meshAneurysm, Ruptured-
dc.subject.meshCentral Nervous System Cysts-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMagnetic Resonance Imaging-
dc.subject.meshMiddle Aged-
dc.subject.meshPituitary Diseases-
dc.subject.meshTomography, X-Ray-
dc.titleHypophysitis secondary to ruptured Rathke's cyst mimicking neurosarcoidosis.en
dc.typeArticleen
dc.contributor.departmentDepartment of Neurology, Beaumont Hospital, P.O. Box 1297, Beaumont Road, Dublin 9, Ireland. cejaneczko@hotmail.comen
dc.identifier.journalJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasiaen
dc.description.provinceLeinster-

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