Benign prostatic hyperplasia presenting with renal failure--what is the role for transurethral resection of the prostate (TURP)?

Hdl Handle:
http://hdl.handle.net/10147/127626
Title:
Benign prostatic hyperplasia presenting with renal failure--what is the role for transurethral resection of the prostate (TURP)?
Authors:
Thomas, A Z; Thomas, A A; Conlon, P; Hickey, D; Little, D M
Affiliation:
Department of Urology and Transplantation, Beaumont Hospital, Beaumont, Dublin. arunthomas75@gmail.com
Citation:
Benign prostatic hyperplasia presenting with renal failure--what is the role for transurethral resection of the prostate (TURP)? 2009, 102 (2):43-4 Ir Med J
Journal:
Irish medical journal
Issue Date:
Feb-2009
URI:
http://hdl.handle.net/10147/127626
PubMed ID:
19405316
Abstract:
The aim of the study was to determine the role of transurethralresection of prostate (TURP) in normalising renal function in men presenting with obstructive renal failure secondary to benign prostatic hyperplasia. We reviewed the cases of 14 men who presented in the last 5 years with renal impairment associated with symptoms of bladder outflow obstruction and radiological evidence of obstructive uropathy. The mean serum creatinine at presentation was 632 ng/mL (range 1299 - 225). The mean age at presentation was 68.2 years (range 50 - 83 years). Duration of symptoms prior to presentation ranged between 1 - 118 months (mean 21.5 months). Following catheter insertion, all patients underwent TURP. Six of the 14 patients required dialysis prior to surgery. Histology of the resected prostate confirmed benign prostatic hypertrophy and/or hyperplasia in all cases. Patients with carcinoma of the prostate were excluded from the study. Following TURP, 2 of the 14 men (14%) failed to void spontaneously following removal of catheter - one patient performs clean self intermittent catheterization (CSIC), the other man has an in-dwelling catheter in situ. One patient died 7 months following TURP due to a myocardial infarction. However, 8 patients, (57%) remained dialysis dependent following TURP. Two of these patients have since undergone successful renal transplantation. Of the remaining 6 patients, only 3 have normal renal function with the other 3 experiencing moderately elevated serum creatinine (range 236 - 344 ng/mL). In patients presenting with renal failure due to bladder outflow obstruction, TURP restores normal voiding pattern in many cases. However renal failure due to bladder outflow obstruction tends to be more refractory and only 3 of 14 patients experienced return to normal renal function post treatment.
Item Type:
Article
Language:
en
MeSH:
Aged; Aged, 80 and over; Cohort Studies; Humans; Incidence; Ireland; Male; Middle Aged; Prostatic Hyperplasia; Renal Insufficiency; Retrospective Studies; Transurethral Resection of Prostate
ISSN:
0332-3102

Full metadata record

DC FieldValue Language
dc.contributor.authorThomas, A Zen
dc.contributor.authorThomas, A Aen
dc.contributor.authorConlon, Pen
dc.contributor.authorHickey, Den
dc.contributor.authorLittle, D Men
dc.date.accessioned2011-04-07T08:18:50Z-
dc.date.available2011-04-07T08:18:50Z-
dc.date.issued2009-02-
dc.identifier.citationBenign prostatic hyperplasia presenting with renal failure--what is the role for transurethral resection of the prostate (TURP)? 2009, 102 (2):43-4 Ir Med Jen
dc.identifier.issn0332-3102-
dc.identifier.pmid19405316-
dc.identifier.urihttp://hdl.handle.net/10147/127626-
dc.description.abstractThe aim of the study was to determine the role of transurethralresection of prostate (TURP) in normalising renal function in men presenting with obstructive renal failure secondary to benign prostatic hyperplasia. We reviewed the cases of 14 men who presented in the last 5 years with renal impairment associated with symptoms of bladder outflow obstruction and radiological evidence of obstructive uropathy. The mean serum creatinine at presentation was 632 ng/mL (range 1299 - 225). The mean age at presentation was 68.2 years (range 50 - 83 years). Duration of symptoms prior to presentation ranged between 1 - 118 months (mean 21.5 months). Following catheter insertion, all patients underwent TURP. Six of the 14 patients required dialysis prior to surgery. Histology of the resected prostate confirmed benign prostatic hypertrophy and/or hyperplasia in all cases. Patients with carcinoma of the prostate were excluded from the study. Following TURP, 2 of the 14 men (14%) failed to void spontaneously following removal of catheter - one patient performs clean self intermittent catheterization (CSIC), the other man has an in-dwelling catheter in situ. One patient died 7 months following TURP due to a myocardial infarction. However, 8 patients, (57%) remained dialysis dependent following TURP. Two of these patients have since undergone successful renal transplantation. Of the remaining 6 patients, only 3 have normal renal function with the other 3 experiencing moderately elevated serum creatinine (range 236 - 344 ng/mL). In patients presenting with renal failure due to bladder outflow obstruction, TURP restores normal voiding pattern in many cases. However renal failure due to bladder outflow obstruction tends to be more refractory and only 3 of 14 patients experienced return to normal renal function post treatment.-
dc.language.isoenen
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshCohort Studies-
dc.subject.meshHumans-
dc.subject.meshIncidence-
dc.subject.meshIreland-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshProstatic Hyperplasia-
dc.subject.meshRenal Insufficiency-
dc.subject.meshRetrospective Studies-
dc.subject.meshTransurethral Resection of Prostate-
dc.titleBenign prostatic hyperplasia presenting with renal failure--what is the role for transurethral resection of the prostate (TURP)?en
dc.typeArticleen
dc.contributor.departmentDepartment of Urology and Transplantation, Beaumont Hospital, Beaumont, Dublin. arunthomas75@gmail.comen
dc.identifier.journalIrish medical journalen
dc.description.provinceLeinster-
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