Diagnosis and management of asthma in older adults.

Hdl Handle:
http://hdl.handle.net/10147/127507
Title:
Diagnosis and management of asthma in older adults.
Authors:
Chotirmall, Sanjay Haresh; Watts, Michael; Branagan, Peter; Donegan, Ciaran F; Moore, Allan; McElvaney, Noel Gerard
Affiliation:
Department of Medicine, Respiratory Research Division, Education & Research Centre, Beaumont Hospital, Dublin 9, Republic of Ireland. schotirmall@rcsi.ie
Citation:
Diagnosis and management of asthma in older adults. 2009, 57 (5):901-9 J Am Geriatr Soc
Journal:
Journal of the American Geriatrics Society
Issue Date:
May-2009
URI:
http://hdl.handle.net/10147/127507
PubMed ID:
19484848
Abstract:
Despite comprehensive guidelines established by the European Global Initiative for Asthma and the U.S. National Asthma Education and Prevention Program on the diagnosis and management of asthma, its mortality in older adults continues to rise. Diagnostic and therapeutic problems contribute to older patients being inadequately treated. The diagnosis of asthma rests on the history and characteristic pulmonary function testing (PFT) with the demonstration of reversible airway obstruction, but there are unique problems in performing this test in older patients and in its interpretation. This review aims to address the difficulties in performing and interpreting PFT in older patients because of the effects of age-related changes in lung function on respiratory physiology. The concept of "airway remodeling" resulting in "fixed obstructive" PFT and the relevance of atopy in older people with asthma are assessed. There are certain therapeutic issues unique to older patients with asthma, including the increased probability of adverse effects in the setting of multiple comorbidities and issues surrounding effective drug delivery. The use of beta 2-agonist, anticholinergic, corticosteroid, and anti-immunoglobulin E treatments are discussed in the context of these therapeutic issues.
Item Type:
Article
Language:
en
MeSH:
Aged; Anti-Asthmatic Agents; Asthma; Drug Delivery Systems; Humans; Respiratory Function Tests
ISSN:
1532-5415

Full metadata record

DC FieldValue Language
dc.contributor.authorChotirmall, Sanjay Hareshen
dc.contributor.authorWatts, Michaelen
dc.contributor.authorBranagan, Peteren
dc.contributor.authorDonegan, Ciaran Fen
dc.contributor.authorMoore, Allanen
dc.contributor.authorMcElvaney, Noel Gerarden
dc.date.accessioned2011-04-06T14:54:55Z-
dc.date.available2011-04-06T14:54:55Z-
dc.date.issued2009-05-
dc.identifier.citationDiagnosis and management of asthma in older adults. 2009, 57 (5):901-9 J Am Geriatr Socen
dc.identifier.issn1532-5415-
dc.identifier.pmid19484848-
dc.identifier.urihttp://hdl.handle.net/10147/127507-
dc.description.abstractDespite comprehensive guidelines established by the European Global Initiative for Asthma and the U.S. National Asthma Education and Prevention Program on the diagnosis and management of asthma, its mortality in older adults continues to rise. Diagnostic and therapeutic problems contribute to older patients being inadequately treated. The diagnosis of asthma rests on the history and characteristic pulmonary function testing (PFT) with the demonstration of reversible airway obstruction, but there are unique problems in performing this test in older patients and in its interpretation. This review aims to address the difficulties in performing and interpreting PFT in older patients because of the effects of age-related changes in lung function on respiratory physiology. The concept of "airway remodeling" resulting in "fixed obstructive" PFT and the relevance of atopy in older people with asthma are assessed. There are certain therapeutic issues unique to older patients with asthma, including the increased probability of adverse effects in the setting of multiple comorbidities and issues surrounding effective drug delivery. The use of beta 2-agonist, anticholinergic, corticosteroid, and anti-immunoglobulin E treatments are discussed in the context of these therapeutic issues.-
dc.language.isoenen
dc.subject.meshAged-
dc.subject.meshAnti-Asthmatic Agents-
dc.subject.meshAsthma-
dc.subject.meshDrug Delivery Systems-
dc.subject.meshHumans-
dc.subject.meshRespiratory Function Tests-
dc.titleDiagnosis and management of asthma in older adults.en
dc.typeArticleen
dc.contributor.departmentDepartment of Medicine, Respiratory Research Division, Education & Research Centre, Beaumont Hospital, Dublin 9, Republic of Ireland. schotirmall@rcsi.ieen
dc.identifier.journalJournal of the American Geriatrics Societyen
dc.description.provinceLeinster-

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