Hdl Handle:
http://hdl.handle.net/10147/127446
Title:
Rings in the neonate
Authors:
Hackett, CB; McAleer, MA; O'Donnell, BF
Publisher:
Irish Medical Journal
Issue Date:
Feb-2011
URI:
http://hdl.handle.net/10147/127446
Item Type:
Article
Language:
en
Description:
Neonatal lupus erythematosus (NLE) is an uncommon disease of the neonate. It is believed to be caused by the transplacental passage of maternal autoantibodies to the ribonucleoproteins (Ro/SSA, La/SSB or rarely U1RNP) as these are almost invariably present in NLE sera. 1 The most common clinical manifestations include cutaneous lupus lesions and congenital complete heart block. Hepatobiliary and haematologic abnormalities are reported less frequently. 2,3 We describe a patient with cutaneous NLE to illustrate and raise awareness of the characteristic annular eruption of this condition. We also emphasize the need for thorough investigation for concomitant organ involvement and for maternal education regarding risk in future pregnancies.
Keywords:
NEONATE; IMMUNODEFICIENCY; IMMUNE DISORDER
Sponsors:
Reproduced with permission from the Irish Medical Journal

Full metadata record

DC FieldValue Language
dc.contributor.authorHackett, CBen
dc.contributor.authorMcAleer, MAen
dc.contributor.authorO'Donnell, BFen
dc.date.accessioned2011-04-06T13:19:45Z-
dc.date.available2011-04-06T13:19:45Z-
dc.date.issued2011-02-
dc.identifier.urihttp://hdl.handle.net/10147/127446-
dc.descriptionNeonatal lupus erythematosus (NLE) is an uncommon disease of the neonate. It is believed to be caused by the transplacental passage of maternal autoantibodies to the ribonucleoproteins (Ro/SSA, La/SSB or rarely U1RNP) as these are almost invariably present in NLE sera. 1 The most common clinical manifestations include cutaneous lupus lesions and congenital complete heart block. Hepatobiliary and haematologic abnormalities are reported less frequently. 2,3 We describe a patient with cutaneous NLE to illustrate and raise awareness of the characteristic annular eruption of this condition. We also emphasize the need for thorough investigation for concomitant organ involvement and for maternal education regarding risk in future pregnancies.en
dc.description.sponsorshipReproduced with permission from the Irish Medical Journalen
dc.language.isoenen
dc.publisherIrish Medical Journalen
dc.subjectNEONATEen
dc.subjectIMMUNODEFICIENCYen
dc.subjectIMMUNE DISORDERen
dc.titleRings in the neonateen
dc.typeArticleen
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