Bile acids in regulation of intestinal physiology.

Hdl Handle:
http://hdl.handle.net/10147/127273
Title:
Bile acids in regulation of intestinal physiology.
Authors:
Keating, Niamh; Keely, Stephen J
Affiliation:
Department of Molecular Medicine, Royal College of Surgeons in Ireland Education and Research Centre, Smurfit Building, Beaumont Hospital, Dublin 9, Ireland.
Citation:
Bile acids in regulation of intestinal physiology. 2009, 11 (5):375-82 Curr Gastroenterol Rep
Journal:
Current gastroenterology reports
Issue Date:
Oct-2009
URI:
http://hdl.handle.net/10147/127273
PubMed ID:
19765365
Abstract:
In addition to their roles in facilitating lipid digestion and absorption, bile acids are recognized as important regulators of intestinal function. Exposure to bile acids can dramatically influence intestinal transport and barrier properties; in recent years, they have also become appreciated as important factors in regulating cell growth and survival. Indeed, few cells reside within the intestinal mucosa that are not altered to some degree by exposure to bile acids. The past decade saw great advances in the knowledge of how bile acids exert their actions at the cellular and molecular levels. In this review, we summarize the current understanding of the role of bile acids in regulation of intestinal physiology.
Item Type:
Article
Language:
en
MeSH:
Animals; Bile; Bile Acids and Salts; Dietary Fats; Digestion; Enterocytes; Gastrointestinal Motility; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Intestines; Liver; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Signal Transduction
ISSN:
1534-312X

Full metadata record

DC FieldValue Language
dc.contributor.authorKeating, Niamhen
dc.contributor.authorKeely, Stephen Jen
dc.date.accessioned2011-04-05T15:33:42Z-
dc.date.available2011-04-05T15:33:42Z-
dc.date.issued2009-10-
dc.identifier.citationBile acids in regulation of intestinal physiology. 2009, 11 (5):375-82 Curr Gastroenterol Repen
dc.identifier.issn1534-312X-
dc.identifier.pmid19765365-
dc.identifier.urihttp://hdl.handle.net/10147/127273-
dc.description.abstractIn addition to their roles in facilitating lipid digestion and absorption, bile acids are recognized as important regulators of intestinal function. Exposure to bile acids can dramatically influence intestinal transport and barrier properties; in recent years, they have also become appreciated as important factors in regulating cell growth and survival. Indeed, few cells reside within the intestinal mucosa that are not altered to some degree by exposure to bile acids. The past decade saw great advances in the knowledge of how bile acids exert their actions at the cellular and molecular levels. In this review, we summarize the current understanding of the role of bile acids in regulation of intestinal physiology.-
dc.language.isoenen
dc.subject.meshAnimals-
dc.subject.meshBile-
dc.subject.meshBile Acids and Salts-
dc.subject.meshDietary Fats-
dc.subject.meshDigestion-
dc.subject.meshEnterocytes-
dc.subject.meshGastrointestinal Motility-
dc.subject.meshHumans-
dc.subject.meshIntestinal Absorption-
dc.subject.meshIntestinal Mucosa-
dc.subject.meshIntestine, Small-
dc.subject.meshIntestines-
dc.subject.meshLiver-
dc.subject.meshReceptors, Cytoplasmic and Nuclear-
dc.subject.meshReceptors, G-Protein-Coupled-
dc.subject.meshSignal Transduction-
dc.titleBile acids in regulation of intestinal physiology.en
dc.typeArticleen
dc.contributor.departmentDepartment of Molecular Medicine, Royal College of Surgeons in Ireland Education and Research Centre, Smurfit Building, Beaumont Hospital, Dublin 9, Ireland.en
dc.identifier.journalCurrent gastroenterology reportsen
dc.description.provinceLeinster-

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.