Ultraviolet radiation and immunosuppression.

Hdl Handle:
http://hdl.handle.net/10147/127270
Title:
Ultraviolet radiation and immunosuppression.
Authors:
Murphy, G M
Affiliation:
Department of Dermatology, Beaumont & Mater Misericordiae Hospital, Dublin, Ireland. gmurphyoffice@eircom.net
Citation:
Ultraviolet radiation and immunosuppression. 2009, 161 Suppl 3:90-5 Br. J. Dermatol.
Journal:
The British journal of dermatology
Issue Date:
Nov-2009
URI:
http://hdl.handle.net/10147/127270
DOI:
10.1111/j.1365-2133.2009.09455.x
PubMed ID:
19775363
Abstract:
Ultraviolet (UV) radiation is a complete carcinogen. The effects of UV radiation are mediated via direct damage to cellular DNA in the skin and suppression of image surveillance mechanisms. In the context of organ transplantation, addiction of drugs which suppress the immune system add greatly to the carcinogenicity of UV radiation. This review considers the mechanisms of such effects.
Item Type:
Article
Language:
en
MeSH:
Animals; Apoptosis; DNA Damage; Humans; Immunosuppression; Mice; Mice, Inbred C57BL; Neoplasms, Radiation-Induced; Skin; Ultraviolet Rays
ISSN:
1365-2133

Full metadata record

DC FieldValue Language
dc.contributor.authorMurphy, G Men
dc.date.accessioned2011-04-05T15:28:42Z-
dc.date.available2011-04-05T15:28:42Z-
dc.date.issued2009-11-
dc.identifier.citationUltraviolet radiation and immunosuppression. 2009, 161 Suppl 3:90-5 Br. J. Dermatol.en
dc.identifier.issn1365-2133-
dc.identifier.pmid19775363-
dc.identifier.doi10.1111/j.1365-2133.2009.09455.x-
dc.identifier.urihttp://hdl.handle.net/10147/127270-
dc.description.abstractUltraviolet (UV) radiation is a complete carcinogen. The effects of UV radiation are mediated via direct damage to cellular DNA in the skin and suppression of image surveillance mechanisms. In the context of organ transplantation, addiction of drugs which suppress the immune system add greatly to the carcinogenicity of UV radiation. This review considers the mechanisms of such effects.-
dc.language.isoenen
dc.subject.meshAnimals-
dc.subject.meshApoptosis-
dc.subject.meshDNA Damage-
dc.subject.meshHumans-
dc.subject.meshImmunosuppression-
dc.subject.meshMice-
dc.subject.meshMice, Inbred C57BL-
dc.subject.meshNeoplasms, Radiation-Induced-
dc.subject.meshSkin-
dc.subject.meshUltraviolet Rays-
dc.titleUltraviolet radiation and immunosuppression.en
dc.typeArticleen
dc.contributor.departmentDepartment of Dermatology, Beaumont & Mater Misericordiae Hospital, Dublin, Ireland. gmurphyoffice@eircom.neten
dc.identifier.journalThe British journal of dermatologyen
dc.description.provinceLeinster-

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