Acromegaly associated with gangliocytoma.

Hdl Handle:
http://hdl.handle.net/10147/127248
Title:
Acromegaly associated with gangliocytoma.
Authors:
Crowley, R K; Al-Derazi, Y; Lynch, K; Rawluk, D; Thompson, C J; Farrell, M; Agha, A
Affiliation:
Academic Department of Endocrinology, Beaumont Hospital, Dublin 9, Ireland, rachelcrowley@hotmail.com.
Citation:
Acromegaly associated with gangliocytoma. 2009: Ir J Med Sci
Journal:
Irish journal of medical science
Issue Date:
30-Sep-2009
URI:
http://hdl.handle.net/10147/127248
DOI:
10.1007/s11845-009-0433-2
PubMed ID:
19789938
Abstract:
BACKGROUND: Acromegaly secondary to growth hormone-releasing hormone (GHRH) excess is rare. AIMS/CASE DESCRIPTION: We report two patients with acromegaly who were diagnosed with sellar gangliocytomas that were immunopositive for GHRH. Tumour tissue persisted after debulking surgery and in the second case this was associated with persistent growth hormone hypersecretion, successfully suppressed by a somatostatin analogue. CONCLUSIONS: The development of functional pituitary adenomas in association with sellar gangliocytomas is poorly understood. We present a brief discussion of the possible aetiology of these unusual pituitary tumours.
Item Type:
Article In Press
ISSN:
1863-4362

Full metadata record

DC FieldValue Language
dc.contributor.authorCrowley, R Ken
dc.contributor.authorAl-Derazi, Yen
dc.contributor.authorLynch, Ken
dc.contributor.authorRawluk, Den
dc.contributor.authorThompson, C Jen
dc.contributor.authorFarrell, Men
dc.contributor.authorAgha, Aen
dc.date.accessioned2011-04-05T15:25:18Z-
dc.date.available2011-04-05T15:25:18Z-
dc.date.issued2009-09-30-
dc.identifier.citationAcromegaly associated with gangliocytoma. 2009: Ir J Med Scien
dc.identifier.issn1863-4362-
dc.identifier.pmid19789938-
dc.identifier.doi10.1007/s11845-009-0433-2-
dc.identifier.urihttp://hdl.handle.net/10147/127248-
dc.description.abstractBACKGROUND: Acromegaly secondary to growth hormone-releasing hormone (GHRH) excess is rare. AIMS/CASE DESCRIPTION: We report two patients with acromegaly who were diagnosed with sellar gangliocytomas that were immunopositive for GHRH. Tumour tissue persisted after debulking surgery and in the second case this was associated with persistent growth hormone hypersecretion, successfully suppressed by a somatostatin analogue. CONCLUSIONS: The development of functional pituitary adenomas in association with sellar gangliocytomas is poorly understood. We present a brief discussion of the possible aetiology of these unusual pituitary tumours.-
dc.languageENG-
dc.titleAcromegaly associated with gangliocytoma.en
dc.typeArticle In Pressen
dc.contributor.departmentAcademic Department of Endocrinology, Beaumont Hospital, Dublin 9, Ireland, rachelcrowley@hotmail.com.en
dc.identifier.journalIrish journal of medical scienceen
dc.description.provinceLeinster-

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