High incidence of osteoporosis and fractures in an aging post-polio population.

Hdl Handle:
http://hdl.handle.net/10147/127247
Title:
High incidence of osteoporosis and fractures in an aging post-polio population.
Authors:
Mohammad, Ausaf F; Khan, Khalid Ali; Galvin, Leo; Hardiman, Orla; O'Connell, Paul G
Affiliation:
Department of Rheumatology, Beaumont Hospital, Dublin, Ireland. ausafmohammad@gmail.com
Citation:
High incidence of osteoporosis and fractures in an aging post-polio population. 2009, 62 (6):369-74 Eur. Neurol.
Journal:
European neurology
Issue Date:
2009
URI:
http://hdl.handle.net/10147/127247
DOI:
10.1159/000242444
PubMed ID:
19797901
Abstract:
Since the polio epidemic in Ireland in the 1950s, most polio survivors are approaching into the 6th and 7th decade of their lives. There is little data about bone density and risk of fractures in these patients. In 2006, we undertook an audit of post-polio patients attending rheumatology and neurology outpatient clinics in a university teaching hospital. Our aim was to determine the prevalence of osteoporosis (OP), falls and fractures and to evaluate the association of bone density with other potential contributing factors to OP.; Over a 6-month period, 50 post-polio patients attending outpatient clinics completed a questionnaire, and subsequently their medical records were reviewed. Demographic data and details of treatment were extracted. The patients underwent a dual-energy X-ray absorptiometry scanning to quantify bone mineral density.; Thirty subjects (60%) were females (26 were postmenopausal). The average age of females was 60 +/- 13.4 years and of men 59 +/- 16.8 years. Overall, 41 (82%) of the patients had experienced falls in the last 5 years and 32 (64%) in the last 6 months. Nineteen (38%) of the patients had experienced a bone fracture in the last 5 years. Based on the bone mineral density data, 28 (56%) of the patients were diagnosed with OP and 20 (40%) had osteopenia, but only 8 (16%) received anti-resorptive therapy. Of the 19 patients who had a fracture, 14 (74%) had OP and 5 (26%) had osteopenia, of whom only 6 (32%) received anti-resorptive therapy. Eight out of 9 fractures of the neck of femur occurred in the weaker leg.; Post-polio patients are a high-risk group for fracture, and thus bone density assessment, review of falls risk and therapeutic intervention should be considered for all patients. Both osteopenia and OP are associated with increased fracture risk.
Item Type:
Article
Language:
en
MeSH:
Accidental Falls; Bone Density; Female; Fractures, Bone; Humans; Incidence; Ireland; Male; Middle Aged; Osteoporosis; Postpoliomyelitis Syndrome; Questionnaires; Risk Factors; Smoking
ISSN:
1421-9913

Full metadata record

DC FieldValue Language
dc.contributor.authorMohammad, Ausaf Fen
dc.contributor.authorKhan, Khalid Alien
dc.contributor.authorGalvin, Leoen
dc.contributor.authorHardiman, Orlaen
dc.contributor.authorO'Connell, Paul Gen
dc.date.accessioned2011-04-05T15:24:30Z-
dc.date.available2011-04-05T15:24:30Z-
dc.date.issued2009-
dc.identifier.citationHigh incidence of osteoporosis and fractures in an aging post-polio population. 2009, 62 (6):369-74 Eur. Neurol.en
dc.identifier.issn1421-9913-
dc.identifier.pmid19797901-
dc.identifier.doi10.1159/000242444-
dc.identifier.urihttp://hdl.handle.net/10147/127247-
dc.description.abstractSince the polio epidemic in Ireland in the 1950s, most polio survivors are approaching into the 6th and 7th decade of their lives. There is little data about bone density and risk of fractures in these patients. In 2006, we undertook an audit of post-polio patients attending rheumatology and neurology outpatient clinics in a university teaching hospital. Our aim was to determine the prevalence of osteoporosis (OP), falls and fractures and to evaluate the association of bone density with other potential contributing factors to OP.-
dc.description.abstractOver a 6-month period, 50 post-polio patients attending outpatient clinics completed a questionnaire, and subsequently their medical records were reviewed. Demographic data and details of treatment were extracted. The patients underwent a dual-energy X-ray absorptiometry scanning to quantify bone mineral density.-
dc.description.abstractThirty subjects (60%) were females (26 were postmenopausal). The average age of females was 60 +/- 13.4 years and of men 59 +/- 16.8 years. Overall, 41 (82%) of the patients had experienced falls in the last 5 years and 32 (64%) in the last 6 months. Nineteen (38%) of the patients had experienced a bone fracture in the last 5 years. Based on the bone mineral density data, 28 (56%) of the patients were diagnosed with OP and 20 (40%) had osteopenia, but only 8 (16%) received anti-resorptive therapy. Of the 19 patients who had a fracture, 14 (74%) had OP and 5 (26%) had osteopenia, of whom only 6 (32%) received anti-resorptive therapy. Eight out of 9 fractures of the neck of femur occurred in the weaker leg.-
dc.description.abstractPost-polio patients are a high-risk group for fracture, and thus bone density assessment, review of falls risk and therapeutic intervention should be considered for all patients. Both osteopenia and OP are associated with increased fracture risk.-
dc.language.isoenen
dc.subject.meshAccidental Falls-
dc.subject.meshBone Density-
dc.subject.meshFemale-
dc.subject.meshFractures, Bone-
dc.subject.meshHumans-
dc.subject.meshIncidence-
dc.subject.meshIreland-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshOsteoporosis-
dc.subject.meshPostpoliomyelitis Syndrome-
dc.subject.meshQuestionnaires-
dc.subject.meshRisk Factors-
dc.subject.meshSmoking-
dc.titleHigh incidence of osteoporosis and fractures in an aging post-polio population.en
dc.typeArticleen
dc.contributor.departmentDepartment of Rheumatology, Beaumont Hospital, Dublin, Ireland. ausafmohammad@gmail.comen
dc.identifier.journalEuropean neurologyen
dc.description.provinceLeinster-

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