Prospective, randomized, controlled trial of thoracic epidural or patient-controlled opiate analgesia on perioperative quality of life.

Hdl Handle:
http://hdl.handle.net/10147/127141
Title:
Prospective, randomized, controlled trial of thoracic epidural or patient-controlled opiate analgesia on perioperative quality of life.
Authors:
Ali, M; Winter, D C; Hanly, A M; O'Hagan, C; Keaveny, J; Broe, P
Affiliation:
Department of Surgery, Beaumont Hospital, Institute for Clinical Outcomes and Education (iCORE), St Vincent's University Hospital, Elm Park, Dublin 9, Ireland.
Citation:
Prospective, randomized, controlled trial of thoracic epidural or patient-controlled opiate analgesia on perioperative quality of life. 2010, 104 (3):292-7 Br J Anaesth
Journal:
British journal of anaesthesia
Issue Date:
Mar-2010
URI:
http://hdl.handle.net/10147/127141
DOI:
10.1093/bja/aeq006
PubMed ID:
20124282
Additional Links:
http://bja.oxfordjournals.org/content/104/3/292.full.pdf+html
Abstract:
Perioperative epidural analgesia provides continuous pain control and may have advantages over parenteral opiate administration. This study assessed the impact of epidural analgesia on quality of life (QOL) of patients undergoing major surgery.; Sixty patients undergoing thoracic or thoraco-abdominal surgery were studied prospectively. Patients were randomly assigned to receive either thoracic epidural analgesia or patient-controlled i.v. opiate analgesia (PCA) after operation. Visual analogue pain and sedation scores were recorded for the period of the study. QOL health surveys at 24 h (SF-8 acute form) and at 1 week (SF-36) were recorded. Results were examined by uni- and multivariate analyses corrected for the effect of multiple comparisons.; Mean pain scores were significantly lower in the epidural group at most time points. Physical and mental scores in the epidural group were significantly better than the PCA group for both SF-8 and SF-36 QOL health surveys (P<0.001).; Epidural analgesia with local anaesthetic and opioid improves QOL and delivers better analgesia compared with PCA in patients undergoing major thoraco-abdominal surgery.
Item Type:
Article
Language:
en
MeSH:
Abdomen; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Attitude of Health Personnel; Esophagectomy; Female; Health Status Indicators; Humans; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies; Psychometrics; Quality of Life; Thoracotomy; Young Adult
ISSN:
1471-6771

Full metadata record

DC FieldValue Language
dc.contributor.authorAli, Men
dc.contributor.authorWinter, D Cen
dc.contributor.authorHanly, A Men
dc.contributor.authorO'Hagan, Cen
dc.contributor.authorKeaveny, Jen
dc.contributor.authorBroe, Pen
dc.date.accessioned2011-04-05T11:13:48Z-
dc.date.available2011-04-05T11:13:48Z-
dc.date.issued2010-03-
dc.identifier.citationProspective, randomized, controlled trial of thoracic epidural or patient-controlled opiate analgesia on perioperative quality of life. 2010, 104 (3):292-7 Br J Anaesthen
dc.identifier.issn1471-6771-
dc.identifier.pmid20124282-
dc.identifier.doi10.1093/bja/aeq006-
dc.identifier.urihttp://hdl.handle.net/10147/127141-
dc.description.abstractPerioperative epidural analgesia provides continuous pain control and may have advantages over parenteral opiate administration. This study assessed the impact of epidural analgesia on quality of life (QOL) of patients undergoing major surgery.-
dc.description.abstractSixty patients undergoing thoracic or thoraco-abdominal surgery were studied prospectively. Patients were randomly assigned to receive either thoracic epidural analgesia or patient-controlled i.v. opiate analgesia (PCA) after operation. Visual analogue pain and sedation scores were recorded for the period of the study. QOL health surveys at 24 h (SF-8 acute form) and at 1 week (SF-36) were recorded. Results were examined by uni- and multivariate analyses corrected for the effect of multiple comparisons.-
dc.description.abstractMean pain scores were significantly lower in the epidural group at most time points. Physical and mental scores in the epidural group were significantly better than the PCA group for both SF-8 and SF-36 QOL health surveys (P<0.001).-
dc.description.abstractEpidural analgesia with local anaesthetic and opioid improves QOL and delivers better analgesia compared with PCA in patients undergoing major thoraco-abdominal surgery.-
dc.language.isoenen
dc.relation.urlhttp://bja.oxfordjournals.org/content/104/3/292.full.pdf+html-
dc.subject.meshAbdomen-
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshAnalgesia, Epidural-
dc.subject.meshAnalgesia, Patient-Controlled-
dc.subject.meshAnalgesics, Opioid-
dc.subject.meshAttitude of Health Personnel-
dc.subject.meshEsophagectomy-
dc.subject.meshFemale-
dc.subject.meshHealth Status Indicators-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshPain Measurement-
dc.subject.meshPain, Postoperative-
dc.subject.meshPatient Satisfaction-
dc.subject.meshProspective Studies-
dc.subject.meshPsychometrics-
dc.subject.meshQuality of Life-
dc.subject.meshThoracotomy-
dc.subject.meshYoung Adult-
dc.titleProspective, randomized, controlled trial of thoracic epidural or patient-controlled opiate analgesia on perioperative quality of life.en
dc.typeArticleen
dc.contributor.departmentDepartment of Surgery, Beaumont Hospital, Institute for Clinical Outcomes and Education (iCORE), St Vincent's University Hospital, Elm Park, Dublin 9, Ireland.en
dc.identifier.journalBritish journal of anaesthesiaen
dc.description.provinceLeinster-

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