Four country healthcare-associated infection prevalence survey: pneumonia and lower respiratory tract infections.

Hdl Handle:
http://hdl.handle.net/10147/127089
Title:
Four country healthcare-associated infection prevalence survey: pneumonia and lower respiratory tract infections.
Authors:
Humphreys, H; Newcombe, R G; Enstone, J; Smyth, E T M; McIlvenny, G; Davies, E; Spencer, R
Affiliation:
Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, PO Box 9063, Dublin 9, Ireland. hhumphreys@rcsi.ie
Citation:
Four country healthcare-associated infection prevalence survey: pneumonia and lower respiratory tract infections. 2010, 74 (3):266-70 J. Hosp. Infect.
Journal:
The Journal of hospital infection
Issue Date:
Mar-2010
URI:
http://hdl.handle.net/10147/127089
DOI:
10.1016/j.jhin.2009.10.010
PubMed ID:
20153552
Abstract:
In 2006, the Hospital Infection Society was funded by the respective health services in England, Wales, Northern Ireland and the Republic of Ireland to conduct a prevalence survey of healthcare-associated infection (HCAI). Here, we report the prevalence of pneumonia and lower respiratory tract infection other than pneumonia (LRTIOP) in these four countries. The prevalence of all HCAIs was 7.59% (5743 out of 75 694). Nine hundred (15.7%) of these infections were pneumonia, and 402 (7.0%) were LRTIOP. The prevalence of both infections was higher for males than for females, and increased threefold from those aged <35 to those aged >85 years (P<0.001). At the time of the survey or in the preceding seven days, 23.7% and 18.2% of patients with pneumonia and LRTIOP, respectively, were mechanically ventilated compared to 5.2% of patients in the whole study population. Meticillin-resistant Staphylococcus aureus (MRSA) was the cause of pneumonia and LRTIOP in 7.6% and 18.1% of patients, respectively (P<0.001). More patients with LRTIOP (4.2%) had concurrent diarrhoea due to Clostridium difficile compared to patients with pneumonia (2.4%), but this did not reach statistical significance. Other HCAIs were present in 137 (15.2%) of patients with pneumonia and 66 (16.4%) of those with LRTIOP. The results suggest that reducing instrumentation, such as mechanical ventilation where possible, should help reduce infection. The higher prevalence of MRSA as a cause of LRTIOP suggests a lack of specificity in identifying the microbial cause and the association with C. difficile emphasises the need for better use of antibiotics.
Item Type:
Article
Language:
en
MeSH:
Adult; Age Factors; Aged; Aged, 80 and over; Bacteria; Cross Infection; England; Female; Humans; Ireland; Male; Middle Aged; Northern Ireland; Pneumonia, Bacterial; Prevalence; Respiratory Tract Infections; Sex Factors; Wales; Young Adult
ISSN:
1532-2939

Full metadata record

DC FieldValue Language
dc.contributor.authorHumphreys, Hen
dc.contributor.authorNewcombe, R Gen
dc.contributor.authorEnstone, Jen
dc.contributor.authorSmyth, E T Men
dc.contributor.authorMcIlvenny, Gen
dc.contributor.authorDavies, Een
dc.contributor.authorSpencer, Ren
dc.date.accessioned2011-04-05T10:20:08Z-
dc.date.available2011-04-05T10:20:08Z-
dc.date.issued2010-03-
dc.identifier.citationFour country healthcare-associated infection prevalence survey: pneumonia and lower respiratory tract infections. 2010, 74 (3):266-70 J. Hosp. Infect.en
dc.identifier.issn1532-2939-
dc.identifier.pmid20153552-
dc.identifier.doi10.1016/j.jhin.2009.10.010-
dc.identifier.urihttp://hdl.handle.net/10147/127089-
dc.description.abstractIn 2006, the Hospital Infection Society was funded by the respective health services in England, Wales, Northern Ireland and the Republic of Ireland to conduct a prevalence survey of healthcare-associated infection (HCAI). Here, we report the prevalence of pneumonia and lower respiratory tract infection other than pneumonia (LRTIOP) in these four countries. The prevalence of all HCAIs was 7.59% (5743 out of 75 694). Nine hundred (15.7%) of these infections were pneumonia, and 402 (7.0%) were LRTIOP. The prevalence of both infections was higher for males than for females, and increased threefold from those aged <35 to those aged >85 years (P<0.001). At the time of the survey or in the preceding seven days, 23.7% and 18.2% of patients with pneumonia and LRTIOP, respectively, were mechanically ventilated compared to 5.2% of patients in the whole study population. Meticillin-resistant Staphylococcus aureus (MRSA) was the cause of pneumonia and LRTIOP in 7.6% and 18.1% of patients, respectively (P<0.001). More patients with LRTIOP (4.2%) had concurrent diarrhoea due to Clostridium difficile compared to patients with pneumonia (2.4%), but this did not reach statistical significance. Other HCAIs were present in 137 (15.2%) of patients with pneumonia and 66 (16.4%) of those with LRTIOP. The results suggest that reducing instrumentation, such as mechanical ventilation where possible, should help reduce infection. The higher prevalence of MRSA as a cause of LRTIOP suggests a lack of specificity in identifying the microbial cause and the association with C. difficile emphasises the need for better use of antibiotics.-
dc.language.isoenen
dc.subject.meshAdult-
dc.subject.meshAge Factors-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshBacteria-
dc.subject.meshCross Infection-
dc.subject.meshEngland-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshIreland-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshNorthern Ireland-
dc.subject.meshPneumonia, Bacterial-
dc.subject.meshPrevalence-
dc.subject.meshRespiratory Tract Infections-
dc.subject.meshSex Factors-
dc.subject.meshWales-
dc.subject.meshYoung Adult-
dc.titleFour country healthcare-associated infection prevalence survey: pneumonia and lower respiratory tract infections.en
dc.typeArticleen
dc.contributor.departmentDepartment of Clinical Microbiology, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, PO Box 9063, Dublin 9, Ireland. hhumphreys@rcsi.ieen
dc.identifier.journalThe Journal of hospital infectionen
dc.description.provinceLeinster-
All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.