Encapsulating peritoneal sclerosis: experience of a tertiary referral center.

Hdl Handle:
http://hdl.handle.net/10147/126547
Title:
Encapsulating peritoneal sclerosis: experience of a tertiary referral center.
Authors:
Phelan, P J; Walshe, J J; Al-Aradi, A; Garvey, J P; Finnegan, K; O'Kelly, P; McWilliams, J; Ti, J P; Morrin, M M; Morgan, N; Conlon, P J
Affiliation:
Department of Nephrology, Beaumont Hospital, Dublin 9, Ireland. paulphel@gmail.com
Citation:
Encapsulating peritoneal sclerosis: experience of a tertiary referral center. 2010, 32 (4):459-63 Ren Fail
Journal:
Renal failure
Issue Date:
May-2010
URI:
http://hdl.handle.net/10147/126547
DOI:
10.3109/08860221003658274
PubMed ID:
20446784
Abstract:
Encapsulating peritoneal sclerosis (EPS) is arguably the most serious complication of chronic peritoneal dialysis (PD) therapy with extremely high mortality rates. We aimed to establish the rates of EPS and factors associated with its development in a single center.; We retrospectively reviewed the records of all our PD patients from 1 January 1989 until 31 December 2008. All suspected cases were confirmed at laparotomy. Multifactorial models adjusted for potentially confounding variables such as age and sex.; Eleven cases of EPS were identified giving a prevalence rate of 1.98%. Median duration on PD was substantially longer in affected versus unaffected patients (42.5 months versus 13.8 months; p = 0.0002). EPS patients had experienced a mean of 3.54 previous cases of peritonitis (1 infection per year versus 0.71 per year in unaffected patients; p = 0.075). Six patients died (54.5%) due to intra-abdominal sepsis including all five who presented with small bowel obstruction. Three patients had an omentectomy and adhesiolysis performed with a successful outcome.; Our study reinforces the link between duration on PD and EPS. While mortality was high in our cohort, emerging surgical techniques demonstrate a favorable outcome that can be achieved even in severely affected cases.
Item Type:
Article
Language:
en
MeSH:
Adult; Female; Humans; Ireland; Kidney Failure, Chronic; Logistic Models; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritoneal Fibrosis; Prevalence; Retrospective Studies; Risk Factors; Statistics, Nonparametric
ISSN:
1525-6049

Full metadata record

DC FieldValue Language
dc.contributor.authorPhelan, P Jen
dc.contributor.authorWalshe, J Jen
dc.contributor.authorAl-Aradi, Aen
dc.contributor.authorGarvey, J Pen
dc.contributor.authorFinnegan, Ken
dc.contributor.authorO'Kelly, Pen
dc.contributor.authorMcWilliams, Jen
dc.contributor.authorTi, J Pen
dc.contributor.authorMorrin, M Men
dc.contributor.authorMorgan, Nen
dc.contributor.authorConlon, P Jen
dc.date.accessioned2011-03-31T12:52:01Z-
dc.date.available2011-03-31T12:52:01Z-
dc.date.issued2010-05-
dc.identifier.citationEncapsulating peritoneal sclerosis: experience of a tertiary referral center. 2010, 32 (4):459-63 Ren Failen
dc.identifier.issn1525-6049-
dc.identifier.pmid20446784-
dc.identifier.doi10.3109/08860221003658274-
dc.identifier.urihttp://hdl.handle.net/10147/126547-
dc.description.abstractEncapsulating peritoneal sclerosis (EPS) is arguably the most serious complication of chronic peritoneal dialysis (PD) therapy with extremely high mortality rates. We aimed to establish the rates of EPS and factors associated with its development in a single center.-
dc.description.abstractWe retrospectively reviewed the records of all our PD patients from 1 January 1989 until 31 December 2008. All suspected cases were confirmed at laparotomy. Multifactorial models adjusted for potentially confounding variables such as age and sex.-
dc.description.abstractEleven cases of EPS were identified giving a prevalence rate of 1.98%. Median duration on PD was substantially longer in affected versus unaffected patients (42.5 months versus 13.8 months; p = 0.0002). EPS patients had experienced a mean of 3.54 previous cases of peritonitis (1 infection per year versus 0.71 per year in unaffected patients; p = 0.075). Six patients died (54.5%) due to intra-abdominal sepsis including all five who presented with small bowel obstruction. Three patients had an omentectomy and adhesiolysis performed with a successful outcome.-
dc.description.abstractOur study reinforces the link between duration on PD and EPS. While mortality was high in our cohort, emerging surgical techniques demonstrate a favorable outcome that can be achieved even in severely affected cases.-
dc.language.isoenen
dc.subject.meshAdult-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshIreland-
dc.subject.meshKidney Failure, Chronic-
dc.subject.meshLogistic Models-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshPeritoneal Dialysis, Continuous Ambulatory-
dc.subject.meshPeritoneal Fibrosis-
dc.subject.meshPrevalence-
dc.subject.meshRetrospective Studies-
dc.subject.meshRisk Factors-
dc.subject.meshStatistics, Nonparametric-
dc.titleEncapsulating peritoneal sclerosis: experience of a tertiary referral center.en
dc.typeArticleen
dc.contributor.departmentDepartment of Nephrology, Beaumont Hospital, Dublin 9, Ireland. paulphel@gmail.comen
dc.identifier.journalRenal failureen
dc.description.provinceLeinster-
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