20 year old lady with a paraspinal mass.

Hdl Handle:
http://hdl.handle.net/10147/126495
Title:
20 year old lady with a paraspinal mass.
Authors:
O'Toole, Orna; O'Hare, Alan; Grogan, Liam; Bolger, Ciaran; Brett, Francesca M
Affiliation:
Department of Neuropathology, Beaumont Hospital, Dublin, UK.
Citation:
20 year old lady with a paraspinal mass. 2010, 20 (3):683-4 Brain Pathol.
Journal:
Brain pathology (Zurich, Switzerland)
Issue Date:
May-2010
URI:
http://hdl.handle.net/10147/126495
DOI:
10.1111/j.1750-3639.2010.00382.x
PubMed ID:
20522095
Abstract:
A 20 year old female presented with a 4 month history of right upper limb pain and paraesthesias. She had no systemic symptoms and no prior medical or family history of note. MRI revealed a right-sided intradural extramedullary mass extending from C7-T1 and displacing the spinal cord. While awaiting surgery her symptoms progressed to involve the right lower limb. She was re-imaged and the lesion now extended from C5 to T3 with spinal cord compression at C7-T1. The radiological features and recent rapid growth were felt to be in keeping with a large plexiform neurofibroma. The patient underwent emergency resection of the lesion and pathology revealed Hodgkin's Lymphoma (HL)-mixed cellularity type. A mediastinal mass was identified on further imaging and biopsy confirmed the diagnosis of HL-stage IV. The patient is currently undergoing treatment with ABVD chemotherapy. CNS-HL is extremely rare and may occur de novo or in association with systemic disease. Lesions may be parenchymal or dural based and are usually intracranial with an increased risk of CNS involvement in HL-mixed-cellularity type as in our patient. This is the first report in the literature of CNS-HL radiologically mimicking a paraspinal plexiform neurofibroma.
Item Type:
Article
Language:
en
MeSH:
Cervical Vertebrae; Female; Hodgkin Disease; Humans; Spinal Canal; Spinal Cord Neoplasms; Spinal Neoplasms; Young Adult
ISSN:
1750-3639

Full metadata record

DC FieldValue Language
dc.contributor.authorO'Toole, Ornaen
dc.contributor.authorO'Hare, Alanen
dc.contributor.authorGrogan, Liamen
dc.contributor.authorBolger, Ciaranen
dc.contributor.authorBrett, Francesca Men
dc.date.accessioned2011-03-31T09:40:45Z-
dc.date.available2011-03-31T09:40:45Z-
dc.date.issued2010-05-
dc.identifier.citation20 year old lady with a paraspinal mass. 2010, 20 (3):683-4 Brain Pathol.en
dc.identifier.issn1750-3639-
dc.identifier.pmid20522095-
dc.identifier.doi10.1111/j.1750-3639.2010.00382.x-
dc.identifier.urihttp://hdl.handle.net/10147/126495-
dc.description.abstractA 20 year old female presented with a 4 month history of right upper limb pain and paraesthesias. She had no systemic symptoms and no prior medical or family history of note. MRI revealed a right-sided intradural extramedullary mass extending from C7-T1 and displacing the spinal cord. While awaiting surgery her symptoms progressed to involve the right lower limb. She was re-imaged and the lesion now extended from C5 to T3 with spinal cord compression at C7-T1. The radiological features and recent rapid growth were felt to be in keeping with a large plexiform neurofibroma. The patient underwent emergency resection of the lesion and pathology revealed Hodgkin's Lymphoma (HL)-mixed cellularity type. A mediastinal mass was identified on further imaging and biopsy confirmed the diagnosis of HL-stage IV. The patient is currently undergoing treatment with ABVD chemotherapy. CNS-HL is extremely rare and may occur de novo or in association with systemic disease. Lesions may be parenchymal or dural based and are usually intracranial with an increased risk of CNS involvement in HL-mixed-cellularity type as in our patient. This is the first report in the literature of CNS-HL radiologically mimicking a paraspinal plexiform neurofibroma.-
dc.language.isoenen
dc.subject.meshCervical Vertebrae-
dc.subject.meshFemale-
dc.subject.meshHodgkin Disease-
dc.subject.meshHumans-
dc.subject.meshSpinal Canal-
dc.subject.meshSpinal Cord Neoplasms-
dc.subject.meshSpinal Neoplasms-
dc.subject.meshYoung Adult-
dc.title20 year old lady with a paraspinal mass.en
dc.typeArticleen
dc.contributor.departmentDepartment of Neuropathology, Beaumont Hospital, Dublin, UK.en
dc.identifier.journalBrain pathology (Zurich, Switzerland)en
dc.description.provinceLeinster-

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