Comparison of arterial stiffness and microcirculatory changes following abdominal aortic aneurysm grafting.

Hdl Handle:
http://hdl.handle.net/10147/126130
Title:
Comparison of arterial stiffness and microcirculatory changes following abdominal aortic aneurysm grafting.
Authors:
Moloney, M A; McHugh, S; O' Donnell, D H; Casey, R G; Kavanagh, E G; Grace, P A; Fitzgerald, P; Bouchier-Hayes, D J
Affiliation:
Department of Vascular Surgery, Beaumont Hospital, Beaumont Road, Beaumont, Dublin 9, Ireland, tmoloney90@hotmail.com.
Citation:
Comparison of arterial stiffness and microcirculatory changes following abdominal aortic aneurysm grafting. 2010: Ir J Med Sci
Journal:
Irish journal of medical science
Issue Date:
11-Nov-2010
URI:
http://hdl.handle.net/10147/126130
DOI:
10.1007/s11845-010-0513-3
PubMed ID:
21069574
Abstract:
BACKGOUND: Abdominal aortic aneurysm (AAA) surgery provides a unique opportunity to study the impact of arterial stiffness on central haemodynamics, reflected in augmentation index (AI). The aneurysmal aorta is significantly stiffer than undilated age-matched aorta. AIM: We investigated whether replacement of an aneurysmal aorta with a compliant graft would result in a decrease in AI, which would thus decrease myocardial workload parameters. METHODS: Patients undergoing elective open or endovascular AAA repair were assessed with applanation tonometry and laser fluximetry pre-operatively, immediately and long-term post-operatively. RESULTS: Replacement of a small segment of abnormal conduit vessel resulted in improvements in AI, demonstrating that arterial stiffness can be surgically manipulated. CONCLUSIONS: These results reflect a decreased myocardial workload post-aortic grafting. This decrease in AI is important from a risk factor management perspective, and arterial stiffness should become a further recognised and screened for risk factor in patients with known aneurysmal disease.
Item Type:
Article In Press
ISSN:
1863-4362

Full metadata record

DC FieldValue Language
dc.contributor.authorMoloney, M Aen
dc.contributor.authorMcHugh, Sen
dc.contributor.authorO' Donnell, D Hen
dc.contributor.authorCasey, R Gen
dc.contributor.authorKavanagh, E Gen
dc.contributor.authorGrace, P Aen
dc.contributor.authorFitzgerald, Pen
dc.contributor.authorBouchier-Hayes, D Jen
dc.date.accessioned2011-03-29T14:46:28Z-
dc.date.available2011-03-29T14:46:28Z-
dc.date.issued2010-11-11-
dc.identifier.citationComparison of arterial stiffness and microcirculatory changes following abdominal aortic aneurysm grafting. 2010: Ir J Med Scien
dc.identifier.issn1863-4362-
dc.identifier.pmid21069574-
dc.identifier.doi10.1007/s11845-010-0513-3-
dc.identifier.urihttp://hdl.handle.net/10147/126130-
dc.description.abstractBACKGOUND: Abdominal aortic aneurysm (AAA) surgery provides a unique opportunity to study the impact of arterial stiffness on central haemodynamics, reflected in augmentation index (AI). The aneurysmal aorta is significantly stiffer than undilated age-matched aorta. AIM: We investigated whether replacement of an aneurysmal aorta with a compliant graft would result in a decrease in AI, which would thus decrease myocardial workload parameters. METHODS: Patients undergoing elective open or endovascular AAA repair were assessed with applanation tonometry and laser fluximetry pre-operatively, immediately and long-term post-operatively. RESULTS: Replacement of a small segment of abnormal conduit vessel resulted in improvements in AI, demonstrating that arterial stiffness can be surgically manipulated. CONCLUSIONS: These results reflect a decreased myocardial workload post-aortic grafting. This decrease in AI is important from a risk factor management perspective, and arterial stiffness should become a further recognised and screened for risk factor in patients with known aneurysmal disease.-
dc.languageENG-
dc.titleComparison of arterial stiffness and microcirculatory changes following abdominal aortic aneurysm grafting.en
dc.typeArticle In Pressen
dc.contributor.departmentDepartment of Vascular Surgery, Beaumont Hospital, Beaumont Road, Beaumont, Dublin 9, Ireland, tmoloney90@hotmail.com.en
dc.identifier.journalIrish journal of medical scienceen
dc.description.provinceLeinster-

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