The utility of 99mTc-sestamibi scintigraphy in the localisation of parathyroid adenomas in primary hyperparathyroidism.

Hdl Handle:
http://hdl.handle.net/10147/126129
Title:
The utility of 99mTc-sestamibi scintigraphy in the localisation of parathyroid adenomas in primary hyperparathyroidism.
Authors:
Glynn, N; Lynn, N; Donagh, C; Crowley, R K; Smith, D; Thompson, C J; Hill, A D K; Keeling, F; Agha, A
Affiliation:
Division of Endocrinology, Beaumont Hospital, RCSI Medical School, Dublin 9, Ireland.
Citation:
The utility of 99mTc-sestamibi scintigraphy in the localisation of parathyroid adenomas in primary hyperparathyroidism. 2011, 180 (1):191-4 Ir J Med Sci
Journal:
Irish journal of medical science
Issue Date:
Mar-2011
URI:
http://hdl.handle.net/10147/126129
DOI:
10.1007/s11845-010-0641-9
PubMed ID:
21076888
Abstract:
There are conflicting data in the literature about the sensitivity of sestamibi scintigraphy in parathyroid tumour localisation in primary hyperparathyroidism (PHPT).; We aimed to evaluate the overall sensitivity of this modality in parathyroid tumour localisation and to determine clinical and biochemical factors which influence sensitivity of this method.; We performed a retrospective review of 57 patients with a biochemical diagnosis of PHPT who had sestamibi scintigraphy performed.; The sensitivity of sestamibi scanning was 56% in whole group and 63% in those without nodular thyroid disease. Among the patients with confirmed single gland disease (biochemical cure after surgical removal of a single adenoma), sensitivity was 71%. A positive scan was associated with younger age, greater adenoma weight and higher pre-operative serum calcium. Concordance between the sestamibi and neck ultrasonography was 92% accurate in pre-operative tumour localisation.; Sestamibi scintigraphy was more likely to be positive in younger patients without nodular thyroid disease who have larger parathyroid adenomas with more severe hyperparathyroidism.
Item Type:
Article
Language:
en
ISSN:
1863-4362

Full metadata record

DC FieldValue Language
dc.contributor.authorGlynn, Nen
dc.contributor.authorLynn, Nen
dc.contributor.authorDonagh, Cen
dc.contributor.authorCrowley, R Ken
dc.contributor.authorSmith, Den
dc.contributor.authorThompson, C Jen
dc.contributor.authorHill, A D Ken
dc.contributor.authorKeeling, Fen
dc.contributor.authorAgha, Aen
dc.date.accessioned2011-03-29T14:45:06Z-
dc.date.available2011-03-29T14:45:06Z-
dc.date.issued2011-03-
dc.identifier.citationThe utility of 99mTc-sestamibi scintigraphy in the localisation of parathyroid adenomas in primary hyperparathyroidism. 2011, 180 (1):191-4 Ir J Med Scien
dc.identifier.issn1863-4362-
dc.identifier.pmid21076888-
dc.identifier.doi10.1007/s11845-010-0641-9-
dc.identifier.urihttp://hdl.handle.net/10147/126129-
dc.description.abstractThere are conflicting data in the literature about the sensitivity of sestamibi scintigraphy in parathyroid tumour localisation in primary hyperparathyroidism (PHPT).-
dc.description.abstractWe aimed to evaluate the overall sensitivity of this modality in parathyroid tumour localisation and to determine clinical and biochemical factors which influence sensitivity of this method.-
dc.description.abstractWe performed a retrospective review of 57 patients with a biochemical diagnosis of PHPT who had sestamibi scintigraphy performed.-
dc.description.abstractThe sensitivity of sestamibi scanning was 56% in whole group and 63% in those without nodular thyroid disease. Among the patients with confirmed single gland disease (biochemical cure after surgical removal of a single adenoma), sensitivity was 71%. A positive scan was associated with younger age, greater adenoma weight and higher pre-operative serum calcium. Concordance between the sestamibi and neck ultrasonography was 92% accurate in pre-operative tumour localisation.-
dc.description.abstractSestamibi scintigraphy was more likely to be positive in younger patients without nodular thyroid disease who have larger parathyroid adenomas with more severe hyperparathyroidism.-
dc.language.isoenen
dc.titleThe utility of 99mTc-sestamibi scintigraphy in the localisation of parathyroid adenomas in primary hyperparathyroidism.en
dc.typeArticleen
dc.contributor.departmentDivision of Endocrinology, Beaumont Hospital, RCSI Medical School, Dublin 9, Ireland.en
dc.identifier.journalIrish journal of medical scienceen
dc.description.provinceLeinster-
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