Endoscopic ultrasound with fine needle aspiration and biopsy in lung cancer and isolated mediastinal lymphadenopathy.

Hdl Handle:
http://hdl.handle.net/10147/125857
Title:
Endoscopic ultrasound with fine needle aspiration and biopsy in lung cancer and isolated mediastinal lymphadenopathy.
Authors:
Nadarajan, P; Sulaiman, I; Kent, B; Breslin, N; Moloney, E D; Lane, S J
Affiliation:
AMNCH, Tallaght, Dublin 24. sonadarp2@yahoo.ie
Citation:
Endoscopic ultrasound with fine needle aspiration and biopsy in lung cancer and isolated mediastinal lymphadenopathy. 2010, 103 (3):75-7 Ir Med J
Journal:
Irish medical journal
Issue Date:
Mar-2010
URI:
http://hdl.handle.net/10147/125857
PubMed ID:
20666069
Abstract:
Endoscopic ultrasound with fine-needle aspiration and biopsy (EUS-FNAB) is well established in diagnosing and staging lung cancer in patients with mediastinal adenopathy. EUS-FNAB is highly sensitive, less invasive and has lower complication rates when compared to surgical staging of mediastinal nodes. In this study we describe our experience of EUS-FNAB in lung cancer and other causes of mediastinal lymphadenopathy. EUS-FNAB was performed for assessment of PET positive mediastinal lymph nodes between January 2007 and March 2009 in AMNCH. The endpoints of our study were sensitivity and specificity of EUS-FNAB, morbidity and length of hospital stay. Thirty four patients underwent EUS-FNAB during the study period for both diagnosis and staging. Thirty patients had positive lymph node invasion and 4 had no evidence of malignant invasion. In these 4 patients negative cytology was confirmed on mediastinoscopy giving EUS-FNAB a sensitivity and specificity of 100%. EUS-FNAB upstaged the disease in 12 patients. EUS-FNAB is a reliable tool for mediastinal staging in lung cancer, significantly reducing the need for surgical staging procedures in patients with suspected mediastinal involvement.
Item Type:
Article
Language:
en
MeSH:
Aged; Aged, 80 and over; Biopsy, Fine-Needle; Bronchoscopy; Endosonography; Female; Humans; Lung Neoplasms; Lymphatic Diseases; Male; Mediastinal Diseases; Mediastinoscopy; Middle Aged; Neoplasm Staging; Prospective Studies; Sensitivity and Specificity; Tomography, X-Ray Computed
ISSN:
0332-3102

Full metadata record

DC FieldValue Language
dc.contributor.authorNadarajan, Pen
dc.contributor.authorSulaiman, Ien
dc.contributor.authorKent, Ben
dc.contributor.authorBreslin, Nen
dc.contributor.authorMoloney, E Den
dc.contributor.authorLane, S Jen
dc.date.accessioned2011-03-28T14:42:32Z-
dc.date.available2011-03-28T14:42:32Z-
dc.date.issued2010-03-
dc.identifier.citationEndoscopic ultrasound with fine needle aspiration and biopsy in lung cancer and isolated mediastinal lymphadenopathy. 2010, 103 (3):75-7 Ir Med Jen
dc.identifier.issn0332-3102-
dc.identifier.pmid20666069-
dc.identifier.urihttp://hdl.handle.net/10147/125857-
dc.description.abstractEndoscopic ultrasound with fine-needle aspiration and biopsy (EUS-FNAB) is well established in diagnosing and staging lung cancer in patients with mediastinal adenopathy. EUS-FNAB is highly sensitive, less invasive and has lower complication rates when compared to surgical staging of mediastinal nodes. In this study we describe our experience of EUS-FNAB in lung cancer and other causes of mediastinal lymphadenopathy. EUS-FNAB was performed for assessment of PET positive mediastinal lymph nodes between January 2007 and March 2009 in AMNCH. The endpoints of our study were sensitivity and specificity of EUS-FNAB, morbidity and length of hospital stay. Thirty four patients underwent EUS-FNAB during the study period for both diagnosis and staging. Thirty patients had positive lymph node invasion and 4 had no evidence of malignant invasion. In these 4 patients negative cytology was confirmed on mediastinoscopy giving EUS-FNAB a sensitivity and specificity of 100%. EUS-FNAB upstaged the disease in 12 patients. EUS-FNAB is a reliable tool for mediastinal staging in lung cancer, significantly reducing the need for surgical staging procedures in patients with suspected mediastinal involvement.-
dc.language.isoenen
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshBiopsy, Fine-Needle-
dc.subject.meshBronchoscopy-
dc.subject.meshEndosonography-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshLung Neoplasms-
dc.subject.meshLymphatic Diseases-
dc.subject.meshMale-
dc.subject.meshMediastinal Diseases-
dc.subject.meshMediastinoscopy-
dc.subject.meshMiddle Aged-
dc.subject.meshNeoplasm Staging-
dc.subject.meshProspective Studies-
dc.subject.meshSensitivity and Specificity-
dc.subject.meshTomography, X-Ray Computed-
dc.titleEndoscopic ultrasound with fine needle aspiration and biopsy in lung cancer and isolated mediastinal lymphadenopathy.en
dc.typeArticleen
dc.contributor.departmentAMNCH, Tallaght, Dublin 24. sonadarp2@yahoo.ieen
dc.identifier.journalIrish medical journalen

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