Hdl Handle:
http://hdl.handle.net/10147/125832
Title:
Metronidazole-induced pancreatitis.
Authors:
O'Halloran, E; Hogan, A; Mealy, K
Affiliation:
Department of Surgery, Wexford General Hospital, Wexford, Ireland. ohalloranemily@gmail.com
Citation:
Metronidazole-induced pancreatitis. 2010, 2010:523468 HPB Surg
Journal:
HPB surgery : a world journal of hepatic, pancreatic and biliary surgery
Issue Date:
2010
URI:
http://hdl.handle.net/10147/125832
DOI:
10.1155/2010/523468
PubMed ID:
20862338
Abstract:
A 25-year-old caucasian lady presented to the Accident & Emergency department complaining of acute onset severe epigastric pain radiating through to the back with associated nausea and vomiting. A diagnosis of acute pancreatitis was made. Symptoms commenced after the third dose of Metronidazole therapy prescribed for a recurrent periodontal abscess. The patient described a similar episode 10 months previously. On neither occasion were any other medications being taken, there was no history of alcohol abuse and no other gastro-intestinal aetiology could be identified on imaging. Symptoms resolved quickly upon discontinuation of the antibiotic agent. We conclude therefore that Metronidazole can reasonably be identified as the only potential causative agent.; The proportion of cases of pancreatitis caused by drugs is estimated to be around 2% in the general population. The exact mechanism of action of Metronidazole induced pancreatitis is unclear but a trigger role for the drug seems likely.; This case provides the eighth report of Metronidazole induced pancreatitis. All of the cases were reported in females and ran a benign course. Early diagnosis, discontinuation of the drug and supportive care will lead to a successful recovery in the majority of cases.
Item Type:
Article
Language:
en
MeSH:
Adult; Anti-Infective Agents; Female; Humans; Metronidazole; Pancreatitis; Treatment Outcome
ISSN:
1607-8462

Full metadata record

DC FieldValue Language
dc.contributor.authorO'Halloran, Een
dc.contributor.authorHogan, Aen
dc.contributor.authorMealy, Ken
dc.date.accessioned2011-03-28T11:58:18Z-
dc.date.available2011-03-28T11:58:18Z-
dc.date.issued2010-
dc.identifier.citationMetronidazole-induced pancreatitis. 2010, 2010:523468 HPB Surgen
dc.identifier.issn1607-8462-
dc.identifier.pmid20862338-
dc.identifier.doi10.1155/2010/523468-
dc.identifier.urihttp://hdl.handle.net/10147/125832-
dc.description.abstractA 25-year-old caucasian lady presented to the Accident & Emergency department complaining of acute onset severe epigastric pain radiating through to the back with associated nausea and vomiting. A diagnosis of acute pancreatitis was made. Symptoms commenced after the third dose of Metronidazole therapy prescribed for a recurrent periodontal abscess. The patient described a similar episode 10 months previously. On neither occasion were any other medications being taken, there was no history of alcohol abuse and no other gastro-intestinal aetiology could be identified on imaging. Symptoms resolved quickly upon discontinuation of the antibiotic agent. We conclude therefore that Metronidazole can reasonably be identified as the only potential causative agent.-
dc.description.abstractThe proportion of cases of pancreatitis caused by drugs is estimated to be around 2% in the general population. The exact mechanism of action of Metronidazole induced pancreatitis is unclear but a trigger role for the drug seems likely.-
dc.description.abstractThis case provides the eighth report of Metronidazole induced pancreatitis. All of the cases were reported in females and ran a benign course. Early diagnosis, discontinuation of the drug and supportive care will lead to a successful recovery in the majority of cases.-
dc.language.isoenen
dc.subject.meshAdult-
dc.subject.meshAnti-Infective Agents-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMetronidazole-
dc.subject.meshPancreatitis-
dc.subject.meshTreatment Outcome-
dc.titleMetronidazole-induced pancreatitis.en
dc.typeArticleen
dc.contributor.departmentDepartment of Surgery, Wexford General Hospital, Wexford, Ireland. ohalloranemily@gmail.comen
dc.identifier.journalHPB surgery : a world journal of hepatic, pancreatic and biliary surgeryen

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