The caries-preventive effect of chlorhexidine varnish in children and adolescents: a systematic review.

Hdl Handle:
http://hdl.handle.net/10147/124614
Title:
The caries-preventive effect of chlorhexidine varnish in children and adolescents: a systematic review.
Authors:
James, Patrice; Parnell, C; Whelton, H
Affiliation:
Oral Health Services Research Centre, Cork University Dental School and Hospital, Wilton, Cork, Ireland. p.james@ucc.ie
Citation:
The caries-preventive effect of chlorhexidine varnish in children and adolescents: a systematic review. 2010, 44 (4):333-40 Caries Res.
Journal:
Caries research
Issue Date:
2010
URI:
http://hdl.handle.net/10147/124614
DOI:
10.1159/000315346
PubMed ID:
20606432
Abstract:
Our purpose was to systematically review the literature on the effectiveness of chlorhexidine varnish for preventing dental caries in children and adolescents and to determine its effectiveness compared to fluoride varnish.; MEDLINE, EMBASE and the Cochrane Library were searched through December 2009 to identify relevant randomised trials with blind outcome assessment and a minimum duration of 1 year. The search was later updated in MEDLINE and the Cochrane Library to March 19th, 2010. Risk of bias of the included trials was assessed. The primary outcome was the caries increment.; Twelve trials met the inclusion criteria for the review. There was considerable variation between trials in the concentration and frequency of application of the chlorhexidine varnish, in baseline caries levels and in background exposure to fluoride. Six parallel-group trials reported no statistically significant difference in caries increment in permanent teeth with the application of chlorhexidine varnish compared to placebo or no treatment. The results of 4 split-mouth trials were conflicting: 2 trials found no significant difference in caries increment and 2 reported statistically significant results in favour of chlorhexidine varnish. One trial of the effect of chlorhexidine varnish in primary teeth demonstrated a statistically significant reduction in caries increment. The results of 1 trial comparing chlorhexidine varnish with fluoride varnish for preventing caries in adolescents were equivocal.; Evidence regarding the effectiveness of chlorhexidine varnish for preventing caries is inconclusive. Further well-conducted randomised trials are required before chlorhexidine varnish can be recommended for caries prevention.
Item Type:
Article
Language:
en
ISSN:
1421-976X

Full metadata record

DC FieldValue Language
dc.contributor.authorJames, Patriceen
dc.contributor.authorParnell, Cen
dc.contributor.authorWhelton, Hen
dc.date.accessioned2011-03-15T14:47:17Z-
dc.date.available2011-03-15T14:47:17Z-
dc.date.issued2010-
dc.identifier.citationThe caries-preventive effect of chlorhexidine varnish in children and adolescents: a systematic review. 2010, 44 (4):333-40 Caries Res.en
dc.identifier.issn1421-976X-
dc.identifier.pmid20606432-
dc.identifier.doi10.1159/000315346-
dc.identifier.urihttp://hdl.handle.net/10147/124614-
dc.description.abstractOur purpose was to systematically review the literature on the effectiveness of chlorhexidine varnish for preventing dental caries in children and adolescents and to determine its effectiveness compared to fluoride varnish.-
dc.description.abstractMEDLINE, EMBASE and the Cochrane Library were searched through December 2009 to identify relevant randomised trials with blind outcome assessment and a minimum duration of 1 year. The search was later updated in MEDLINE and the Cochrane Library to March 19th, 2010. Risk of bias of the included trials was assessed. The primary outcome was the caries increment.-
dc.description.abstractTwelve trials met the inclusion criteria for the review. There was considerable variation between trials in the concentration and frequency of application of the chlorhexidine varnish, in baseline caries levels and in background exposure to fluoride. Six parallel-group trials reported no statistically significant difference in caries increment in permanent teeth with the application of chlorhexidine varnish compared to placebo or no treatment. The results of 4 split-mouth trials were conflicting: 2 trials found no significant difference in caries increment and 2 reported statistically significant results in favour of chlorhexidine varnish. One trial of the effect of chlorhexidine varnish in primary teeth demonstrated a statistically significant reduction in caries increment. The results of 1 trial comparing chlorhexidine varnish with fluoride varnish for preventing caries in adolescents were equivocal.-
dc.description.abstractEvidence regarding the effectiveness of chlorhexidine varnish for preventing caries is inconclusive. Further well-conducted randomised trials are required before chlorhexidine varnish can be recommended for caries prevention.-
dc.language.isoenen
dc.titleThe caries-preventive effect of chlorhexidine varnish in children and adolescents: a systematic review.en
dc.typeArticleen
dc.contributor.departmentOral Health Services Research Centre, Cork University Dental School and Hospital, Wilton, Cork, Ireland. p.james@ucc.ieen
dc.identifier.journalCaries researchen
dc.description.provinceMunster-

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