Hdl Handle:
http://hdl.handle.net/10147/124496
Title:
Looking in the mouth for Crohn's disease.
Authors:
Rowland, Marion; Fleming, Paddy; Bourke, Billy
Affiliation:
UCD School of Medicine & Medical Science, Crumlin, Dublin, Ireland.
Citation:
Looking in the mouth for Crohn's disease. 2010, 16 (2):332-7 Inflamm. Bowel Dis.
Journal:
Inflammatory bowel diseases
Issue Date:
Feb-2010
URI:
http://hdl.handle.net/10147/124496
DOI:
10.1002/ibd.20983
PubMed ID:
19705418
Abstract:
It is widely acknowledged among gastroenterologists that the oral cavity may be involved in Crohn's disease (CD). However, the specific manifestations are poorly appreciated. Although oral aphthous ulceration is probably not diagnostically useful in patients with suspected CD, disease-specific manifestations do occur and are particularly common in children presenting with CD. These manifestations can be subtle, often are subclinical, yet commonly harbor diagnostically useful material (granulomas). Orofacial granulomatosis (OFG) is conventionally used to describe patients with overt oral disease without obvious involvement of the gastrointestinal tract. However, many patients with OFG have subclinical intestinal CD or will progress to develop overt intestinal CD with time. The management of severe oral disease is challenging and lacks a clear evidence base.
Item Type:
Article
Language:
en
MeSH:
Adult; Child; Crohn Disease; Disease Progression; Humans; Mouth Diseases; Oral Ulcer; Remission, Spontaneous
ISSN:
1536-4844

Full metadata record

DC FieldValue Language
dc.contributor.authorRowland, Marionen
dc.contributor.authorFleming, Paddyen
dc.contributor.authorBourke, Billyen
dc.date.accessioned2011-03-14T15:34:49Z-
dc.date.available2011-03-14T15:34:49Z-
dc.date.issued2010-02-
dc.identifier.citationLooking in the mouth for Crohn's disease. 2010, 16 (2):332-7 Inflamm. Bowel Dis.en
dc.identifier.issn1536-4844-
dc.identifier.pmid19705418-
dc.identifier.doi10.1002/ibd.20983-
dc.identifier.urihttp://hdl.handle.net/10147/124496-
dc.description.abstractIt is widely acknowledged among gastroenterologists that the oral cavity may be involved in Crohn's disease (CD). However, the specific manifestations are poorly appreciated. Although oral aphthous ulceration is probably not diagnostically useful in patients with suspected CD, disease-specific manifestations do occur and are particularly common in children presenting with CD. These manifestations can be subtle, often are subclinical, yet commonly harbor diagnostically useful material (granulomas). Orofacial granulomatosis (OFG) is conventionally used to describe patients with overt oral disease without obvious involvement of the gastrointestinal tract. However, many patients with OFG have subclinical intestinal CD or will progress to develop overt intestinal CD with time. The management of severe oral disease is challenging and lacks a clear evidence base.-
dc.language.isoenen
dc.subject.meshAdult-
dc.subject.meshChild-
dc.subject.meshCrohn Disease-
dc.subject.meshDisease Progression-
dc.subject.meshHumans-
dc.subject.meshMouth Diseases-
dc.subject.meshOral Ulcer-
dc.subject.meshRemission, Spontaneous-
dc.titleLooking in the mouth for Crohn's disease.en
dc.typeArticleen
dc.contributor.departmentUCD School of Medicine & Medical Science, Crumlin, Dublin, Ireland.en
dc.identifier.journalInflammatory bowel diseasesen
dc.description.provinceLeinster-

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