Life course social mobility and risk of upper aerodigestive tract cancer in men.

Hdl Handle:
http://hdl.handle.net/10147/124307
Title:
Life course social mobility and risk of upper aerodigestive tract cancer in men.
Authors:
Schmeisser, N; Conway, D I; McKinney, P A; McMahon, A D; Pohlabeln, H; Marron, M; Benhamou, S; Bouchardy, C; Macfarlane, G J; Macfarlane, T V; Lagiou, P; Lagiou, A; Bencko, V; Holcátová, I; Merletti, F; Richiardi, L; Kjaerheim, K; Agudo, A; Talamini, R; Polesel, J; Canova, C; Simonato, L; Lowry, R; Znaor, A; Healy, C; McCarten, B E; Hashibe, M; Brennan, P; Ahrens, W
Affiliation:
Bremen Institute for Prevention Research and Social Medicine, Linzer Strasse 10, Bremen, Germany. Nils.Schmeisser@bips.uni-bremen.de
Citation:
Life course social mobility and risk of upper aerodigestive tract cancer in men. 2010, 25 (3):173-82 Eur. J. Epidemiol.
Journal:
European journal of epidemiology
Issue Date:
Mar-2010
URI:
http://hdl.handle.net/10147/124307
DOI:
10.1007/s10654-010-9429-5
PubMed ID:
20143252
Abstract:
The aim of this study was to explore associations between social mobility and tumours of the upper aero-digestive tract (UADT), focussing on life-course transitions in social prestige (SP) based on occupational history. 1,796 cases diagnosed between 1993 and 2005 in ten European countries were compared with 1585 controls. SP was classified by the Standard International Occupational Prestige Scale (SIOPS) based on job histories. SIOPS was categorised in high (H), medium (M) and low (L). Time weighted average achieved and transitions between SP with nine trajectories: H --> H, H --> M, H --> L, M --> H, M --> M, M --> L, L --> H, L --> M and L --> L were analysed. Odds ratios (ORs) and 95%-confidence intervals [95%-CIs] were estimated with logistic regression models including age, consumption of fruits/vegetables, study centre, smoking and alcohol consumption. The adjusted OR for the lowest versus the highest of three categories (time weighted average of SP) was 1.28 [1.04-1.56]. The distance of SP widened between cases and controls during working life. The downward trajectory H --> L gave an OR of 1.71 [0.75-3.87] as compared to H --> H. Subjects with M --> M and L --> L trajectories ORs were also elevated relative to subjects with H --> H trajectories. The association between SP and UADT is not fully explained by confounding factors. Downward social trajectory during the life course may be an independent risk factor for UADT cancers.
Item Type:
Article
Language:
en
MeSH:
Adult; Aged; Aged, 80 and over; Europe; Head and Neck Neoplasms; Humans; Interviews as Topic; Male; Middle Aged; Questionnaires; Risk Assessment; Social Class; Social Mobility; Young Adult
ISSN:
1573-7284

Full metadata record

DC FieldValue Language
dc.contributor.authorSchmeisser, Nen
dc.contributor.authorConway, D Ien
dc.contributor.authorMcKinney, P Aen
dc.contributor.authorMcMahon, A Den
dc.contributor.authorPohlabeln, Hen
dc.contributor.authorMarron, Men
dc.contributor.authorBenhamou, Sen
dc.contributor.authorBouchardy, Cen
dc.contributor.authorMacfarlane, G Jen
dc.contributor.authorMacfarlane, T Ven
dc.contributor.authorLagiou, Pen
dc.contributor.authorLagiou, Aen
dc.contributor.authorBencko, Ven
dc.contributor.authorHolcátová, Ien
dc.contributor.authorMerletti, Fen
dc.contributor.authorRichiardi, Len
dc.contributor.authorKjaerheim, Ken
dc.contributor.authorAgudo, Aen
dc.contributor.authorTalamini, Ren
dc.contributor.authorPolesel, Jen
dc.contributor.authorCanova, Cen
dc.contributor.authorSimonato, Len
dc.contributor.authorLowry, Ren
dc.contributor.authorZnaor, Aen
dc.contributor.authorHealy, Cen
dc.contributor.authorMcCarten, B Een
dc.contributor.authorHashibe, Men
dc.contributor.authorBrennan, Pen
dc.contributor.authorAhrens, Wen
dc.date.accessioned2011-03-11T17:00:21Z-
dc.date.available2011-03-11T17:00:21Z-
dc.date.issued2010-03-
dc.identifier.citationLife course social mobility and risk of upper aerodigestive tract cancer in men. 2010, 25 (3):173-82 Eur. J. Epidemiol.en
dc.identifier.issn1573-7284-
dc.identifier.pmid20143252-
dc.identifier.doi10.1007/s10654-010-9429-5-
dc.identifier.urihttp://hdl.handle.net/10147/124307-
dc.description.abstractThe aim of this study was to explore associations between social mobility and tumours of the upper aero-digestive tract (UADT), focussing on life-course transitions in social prestige (SP) based on occupational history. 1,796 cases diagnosed between 1993 and 2005 in ten European countries were compared with 1585 controls. SP was classified by the Standard International Occupational Prestige Scale (SIOPS) based on job histories. SIOPS was categorised in high (H), medium (M) and low (L). Time weighted average achieved and transitions between SP with nine trajectories: H --> H, H --> M, H --> L, M --> H, M --> M, M --> L, L --> H, L --> M and L --> L were analysed. Odds ratios (ORs) and 95%-confidence intervals [95%-CIs] were estimated with logistic regression models including age, consumption of fruits/vegetables, study centre, smoking and alcohol consumption. The adjusted OR for the lowest versus the highest of three categories (time weighted average of SP) was 1.28 [1.04-1.56]. The distance of SP widened between cases and controls during working life. The downward trajectory H --> L gave an OR of 1.71 [0.75-3.87] as compared to H --> H. Subjects with M --> M and L --> L trajectories ORs were also elevated relative to subjects with H --> H trajectories. The association between SP and UADT is not fully explained by confounding factors. Downward social trajectory during the life course may be an independent risk factor for UADT cancers.-
dc.language.isoenen
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshEurope-
dc.subject.meshHead and Neck Neoplasms-
dc.subject.meshHumans-
dc.subject.meshInterviews as Topic-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshQuestionnaires-
dc.subject.meshRisk Assessment-
dc.subject.meshSocial Class-
dc.subject.meshSocial Mobility-
dc.subject.meshYoung Adult-
dc.titleLife course social mobility and risk of upper aerodigestive tract cancer in men.en
dc.typeArticleen
dc.contributor.departmentBremen Institute for Prevention Research and Social Medicine, Linzer Strasse 10, Bremen, Germany. Nils.Schmeisser@bips.uni-bremen.deen
dc.identifier.journalEuropean journal of epidemiologyen
dc.description.provinceLeinster-

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