Periodontitis and type 2 diabetes: is oxidative stress the mechanistic link?

Hdl Handle:
http://hdl.handle.net/10147/124035
Title:
Periodontitis and type 2 diabetes: is oxidative stress the mechanistic link?
Authors:
Allen, E M; Matthews, J B; O'Connor, R; O'Halloran, D; Chapple, I L C
Affiliation:
Dept. of Restorative Dentistry, Cork University Dental School & Hospital, Cork, Ireland. e.allen@ucc.ie
Citation:
Periodontitis and type 2 diabetes: is oxidative stress the mechanistic link? 2009, 54 (2):41-7 Scott Med J
Journal:
Scottish medical journal
Issue Date:
May-2009
URI:
http://hdl.handle.net/10147/124035
PubMed ID:
19530503
Abstract:
Periodontitis is a common, chronic inflammatory disease initiated by bacteria which has an increased prevalence and severity in patients with type 2 diabetes. Recent studies indicate that the co-morbid presence of periodontitis can, in turn, adversely affect diabetic status and the treatment of periodontitis can lead to improved metabolic control in diabetes patients. Current evidence points to a bidirectional interrelationship between diabetes and inflammatory periodontitis. The importance of oxidative stress-inflammatory pathways in the pathogenesis of type 2 diabetes and periodontitis has recently received attention. Given the bidirectional relationship between these two conditions, this review discusses the potential synergistic interactions along the oxidative stress-inflammation axis common to both type 2 diabetes and periodontitis, and the implications of this relationship for diabetic patients.
Item Type:
Article
Language:
en
MeSH:
Diabetes Mellitus, Type 2; Humans; Oxidative Stress; Periodontitis
ISSN:
0036-9330

Full metadata record

DC FieldValue Language
dc.contributor.authorAllen, E Men
dc.contributor.authorMatthews, J Ben
dc.contributor.authorO'Connor, Ren
dc.contributor.authorO'Halloran, Den
dc.contributor.authorChapple, I L Cen
dc.date.accessioned2011-03-09T14:15:32Z-
dc.date.available2011-03-09T14:15:32Z-
dc.date.issued2009-05-
dc.identifier.citationPeriodontitis and type 2 diabetes: is oxidative stress the mechanistic link? 2009, 54 (2):41-7 Scott Med Jen
dc.identifier.issn0036-9330-
dc.identifier.pmid19530503-
dc.identifier.urihttp://hdl.handle.net/10147/124035-
dc.description.abstractPeriodontitis is a common, chronic inflammatory disease initiated by bacteria which has an increased prevalence and severity in patients with type 2 diabetes. Recent studies indicate that the co-morbid presence of periodontitis can, in turn, adversely affect diabetic status and the treatment of periodontitis can lead to improved metabolic control in diabetes patients. Current evidence points to a bidirectional interrelationship between diabetes and inflammatory periodontitis. The importance of oxidative stress-inflammatory pathways in the pathogenesis of type 2 diabetes and periodontitis has recently received attention. Given the bidirectional relationship between these two conditions, this review discusses the potential synergistic interactions along the oxidative stress-inflammation axis common to both type 2 diabetes and periodontitis, and the implications of this relationship for diabetic patients.-
dc.language.isoenen
dc.subject.meshDiabetes Mellitus, Type 2-
dc.subject.meshHumans-
dc.subject.meshOxidative Stress-
dc.subject.meshPeriodontitis-
dc.titlePeriodontitis and type 2 diabetes: is oxidative stress the mechanistic link?en
dc.typeArticleen
dc.contributor.departmentDept. of Restorative Dentistry, Cork University Dental School & Hospital, Cork, Ireland. e.allen@ucc.ieen
dc.identifier.journalScottish medical journalen
dc.description.provinceMunster-

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