Affiliation
Sleep Research Laboratory, St. Vincent's University Hospital, Dublin, Ireland. john.garvey@ucd.ieIssue Date
2010-02MeSH
AlgorithmsCardiovascular Diseases
Continuous Positive Airway Pressure
Equipment Design
Humans
Positive-Pressure Respiration
Quality of Life
Research
Sleep Apnea, Obstructive
Treatment Outcome
Metadata
Show full item recordCitation
Continuous positive airway pressure therapy: new generations. 2010, 131:259-66 Indian J. Med. Res.Journal
The Indian journal of medical researchPubMed ID
20308751Abstract
Continuous positive airway pressure (CPAP) is the treatment of choice for obstructive sleep apnoea syndrome (OSAS). However, CPAP is not tolerated by all patients with OSAS and alternative modes of pressure delivery have been developed to overcome pressure intolerance, thereby improving patient comfort and adherence. Auto-adjustable positive airway pressure (APAP) devices may be utilised for the long-term management of OSAS and may also assist in the initial diagnosis of OSAS and titration of conventional CPAP therapy. Newer modalities such as C-Flex and A-Flex also show promise as treatment options in the future. However, the evidence supporting the use of these alternative modalities remains scant, in particular with regard to long-term cardiovascular outcomes. In addition, not all APAP devices use the same technological algorithms and data supporting individual APAP devices cannot be extrapolated to support all. Further studies are required to validate the roles of APAP, C-Flex and A-Flex. In the interim, standard CPAP therapy should continue as the mainstay of OSAS management.Language
enISSN
0971-5916Collections
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