http://hdl.handle.net/10147/125987 Thu, 23 May 2013 20:22:21 GMT 2013-05-23T20:22:21Z http://www.lenus.ie:80/hse/retrieve/276911/beaumont_badge.png http://hdl.handle.net/10147/125987 http://hdl.handle.net/10147/292492 Title: Financial impact of accurate discharge coding in a liaison psychiatry service. Authors: Jordan, Iain; Barry, Helen; Clancy, Maurice; O'Toole, Desmond; Machale, Siobhan Abstract: Previous research has shown that patients seen by liaison psychiatry services are a complex and expensive patient group and that the psychiatric co-morbidities of hospital inpatients are poorly attested at discharge for assignment to diagnosis-related groups (DRGs). The aim of this study was to investigate the accuracy of discharge coding in a neuropsychiatry liaison population. We also aimed to establish whether or not, had the correct diagnosis been assigned, additional funding would have been allocated to the hospital. Sat, 01 Dec 2012 00:00:00 GMT http://hdl.handle.net/10147/292492 2012-12-01T00:00:00Z http://hdl.handle.net/10147/292491 Title: A comparison of osteoprotegerin with adiponectin and high-sensitivity C-reactive protein (hsCRP) as a marker for insulin resistance. Authors: O'Sullivan, Eoin P; Ashley, David T; Davenport, Colin; Penugonda, Lakshmi; Kelleher, Grainne; Devlin, Niamh; Crowley, Rachel; O'Shea, Paula; Agha, Amar; Thompson, Chris J; O'Gorman, Donal J; Smith, Diarmuid Abstract: Insulin resistance (IR) is associated with low adiponectin and elevated high sensitivity C-reactive protein (hsCRP). Osteoprotegerin (OPG) has been shown to be elevated in type 2 diabetes, but whether it reflects underlying IR is unclear. We aimed to compare the ability of serum OPG with adiponectin and hsCRP to act as a marker for IR in individuals with normal and abnormal glucose tolerance. Tue, 01 Jan 2013 00:00:00 GMT http://hdl.handle.net/10147/292491 2013-01-01T00:00:00Z http://hdl.handle.net/10147/292360 Title: A rare case of recurrent urachal adenocarcinoma of the bladder Authors: Sullivan, JF; Fanning, DM; Cheema, I; Creagh, T Abstract: Urachal carcinoma is a rare, aggressive malignancy accounting for less than 1% of bladder neoplasms. These tumours are usually adenocarcinomas and occur at the dome or anterior wall of the bladder. They often escape early clinical detection, growing for prolonged periods prior to diagnosis, resulting in local invasion and systemic spread before therapeutic intervention is initiated. We present the case of a recurrent urachal carcinoma in a young female. Wed, 01 May 2013 00:00:00 GMT http://hdl.handle.net/10147/292360 2013-05-01T00:00:00Z http://hdl.handle.net/10147/292316 Title: Twenty-year survivors of kidney transplantation. Authors: Traynor, C; Jenkinson, A; Williams, Y; O'Kelly, P; Hickey, D; Denton, M; Magee, C; Conlon, P J Abstract: There have been few studies of patients with renal allografts functioning for more than 20 years. We sought to identify clinical factors associated with ultra long-term (>20 year) renal allograft survival and to describe the clinical features of these patients. We performed a retrospective analysis of the Irish Renal Transplant Database and included 1174 transplants in 1002 patients. There were 255 (21.74%) patients with graft function for 20 years or more. Multivariate analysis identified recipient age (HR 1.01, CI 1.01-1.02), gender (male HR 1.25, CI 1.08-1.45), acute rejection (HR 1.26, CI 1.09-1.45) and transplant type (living related donor vs. deceased donor) (HR 0.52, CI 0.40-0.66) as significantly associated with long-term graft loss. Median serum creatinine was 115 μmol/L. The 5-year graft survival in 20-year survivors was 74.7%. The mean age at death was 62.7 years (±10.6). The most common causes of death were cardiovascular disease and malignancy. The two major causes of graft loss were death (with function) and interstitial fibrosis/tubular atrophy. Comorbidities included skin cancer (36.1%), coronary heart disease (17.3%) and other malignancies (14.5%). This study identifies factors associated with long-term allograft survival and a high rate of morbidity and early mortality in long-term transplant recipients. Sat, 01 Dec 2012 00:00:00 GMT http://hdl.handle.net/10147/292316 2012-12-01T00:00:00Z